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Page 1
Identification of a Novel p53 Modulator Endowed with Antitumoural and Antibacterial Activity through a Scaffold Repurposing Approach.
Nuti E, La Pietra V, Daniele S, Cuffaro D, Ciccone L, Giacomelli C, Cason C, Carotenuto A, D'Amore VM, Pozzo ED, Costa B, Di Leo R, Comar M, Marinelli L, Martini C, Rossello A. Nuti E, et al. Among authors: d amore vm. Pharmaceuticals (Basel). 2022 Oct 26;15(11):1318. doi: 10.3390/ph15111318. Pharmaceuticals (Basel). 2022. PMID: 36355491 Free PMC article.
Targeting the KRAS oncogene: Synthesis, physicochemical and biological evaluation of novel G-Quadruplex DNA binders.
D'Aria F, D'Amore VM, Di Leva FS, Amato J, Caterino M, Russomanno P, Salerno S, Barresi E, De Leo M, Marini AM, Taliani S, Da Settimo F, Salgado GF, Pompili L, Zizza P, Shirasawa S, Novellino E, Biroccio A, Marinelli L, Giancola C. D'Aria F, et al. Eur J Pharm Sci. 2020 Apr 18;149:105337. doi: 10.1016/j.ejps.2020.105337. Online ahead of print. Eur J Pharm Sci. 2020. PMID: 32311457
Disulfide Bond Replacement with 1,4- and 1,5-Disubstituted [1,2,3]-Triazole on C-X-C Chemokine Receptor Type 4 (CXCR4) Peptide Ligands: Small Changes that Make Big Differences.
Tomassi S, Trotta AM, Ieranò C, Merlino F, Messere A, Rea G, Santoro F, Brancaccio D, Carotenuto A, D'Amore VM, Di Leva FS, Novellino E, Cosconati S, Marinelli L, Scala S, Di Maro S. Tomassi S, et al. Chemistry. 2020 Aug 6;26(44):10113-10125. doi: 10.1002/chem.202002468. Epub 2020 Jul 20. Chemistry. 2020. PMID: 32603023
CXCR4 antagonism sensitizes cancer cells to novel indole-based MDM2/4 inhibitors in glioblastoma multiforme.
Daniele S, La Pietra V, Piccarducci R, Pietrobono D, Cavallini C, D'Amore VM, Cerofolini L, Giuntini S, Russomanno P, Puxeddu M, Nalli M, Pedrini M, Fragai M, Luchinat C, Novellino E, Taliani S, La Regina G, Silvestri R, Martini C, Marinelli L. Daniele S, et al. Eur J Pharmacol. 2021 Apr 15;897:173936. doi: 10.1016/j.ejphar.2021.173936. Epub 2021 Feb 10. Eur J Pharmacol. 2021. PMID: 33581134
Interfering with the Tumor-Immune Interface: Making Way for Triazine-Based Small Molecules as Novel PD-L1 Inhibitors.
Russomanno P, Assoni G, Amato J, D'Amore VM, Scaglia R, Brancaccio D, Pedrini M, Polcaro G, La Pietra V, Orlando P, Falzoni M, Cerofolini L, Giuntini S, Fragai M, Pagano B, Donati G, Novellino E, Quintavalle C, Condorelli G, Sabbatino F, Seneci P, Arosio D, Pepe S, Marinelli L. Russomanno P, et al. Among authors: d amore vm. J Med Chem. 2021 Nov 11;64(21):16020-16045. doi: 10.1021/acs.jmedchem.1c01409. Epub 2021 Oct 20. J Med Chem. 2021. PMID: 34670084
Theoretical and experimental studies on the interaction of biphenyl ligands with human and murine PD-L1: Up-to-date clues for drug design.
Donati G, D'Amore VM, Russomanno P, Cerofolini L, Amato J, Marzano S, Salobehaj M, Rizzo D, Assoni G, Carotenuto A, La Pietra V, Arosio D, Seneci P, Fragai M, Brancaccio D, Di Leva FS, Marinelli L. Donati G, et al. Among authors: d amore vm. Comput Struct Biotechnol J. 2023 Jun 8;21:3355-3368. doi: 10.1016/j.csbj.2023.06.006. eCollection 2023. Comput Struct Biotechnol J. 2023. PMID: 37384351 Free PMC article.
A combined approach of structure-based virtual screening and NMR to interrupt the PD-1/PD-L1 axis: Biphenyl-benzimidazole containing compounds as novel PD-L1 inhibitors.
Donati G, Viviano M, D'Amore VM, Cipriano A, Diakogiannaki I, Amato J, Tomassi S, Brancaccio D, Russomanno P, Di Leva FS, Arosio D, Seneci P, Taliani S, Magiera-Mularz K, Musielak B, Skalniak L, Holak TA, Castellano S, La Pietra V, Marinelli L. Donati G, et al. Among authors: d amore vm. Arch Pharm (Weinheim). 2024 Mar;357(3):e2300583. doi: 10.1002/ardp.202300583. Epub 2023 Dec 18. Arch Pharm (Weinheim). 2024. PMID: 38110703 Free article.
Discovery of 2,3-Diaminoindole Derivatives as a Novel Class of NOD Antagonists.
Russo C, Russomanno P, D'Amore VM, Alfano AI, Santoro F, Guzelj S, Gobec M, Amato J, Pagano B, Marinelli L, Carotenuto A, Tron GC, Di Leva FS, Jakopin Ž, Brancaccio D, Giustiniano M. Russo C, et al. Among authors: d amore vm. J Med Chem. 2024 Feb 22;67(4):3004-3017. doi: 10.1021/acs.jmedchem.3c02094. Epub 2024 Feb 1. J Med Chem. 2024. PMID: 38301029
16 results