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Homologous recombination deficiency is inversely correlated with microsatellite instability and identifies immunologically cold tumors in most cancer types.
Budczies J, Kluck K, Beck S, Ourailidis I, Allgäuer M, Menzel M, Kazdal D, Perkhofer L, Kleger A, Schirmacher P, Seufferlein T, Stenzinger A. Budczies J, et al. J Pathol Clin Res. 2022 Jul;8(4):371-382. doi: 10.1002/cjp2.271. Epub 2022 Apr 5. J Pathol Clin Res. 2022. PMID: 35384413 Free PMC article.
Pan-cancer analysis of genomic scar patterns caused by homologous repair deficiency (HRD).
Rempel E, Kluck K, Beck S, Ourailidis I, Kazdal D, Neumann O, Volckmar AL, Kirchner M, Goldschmid H, Pfarr N, Weichert W, Hübschmann D, Fröhling S, Sutter C, Schaaf CP, Schirmacher P, Endris V, Stenzinger A, Budczies J. Rempel E, et al. NPJ Precis Oncol. 2022 Jun 9;6(1):36. doi: 10.1038/s41698-022-00276-6. NPJ Precis Oncol. 2022. PMID: 35681079 Free PMC article.
Correction: Tumour budding-based grading as independent prognostic biomarker in HPV-positive and HPV-negative head and neck cancer.
Stögbauer F, Beck S, Ourailidis I, Hess J, Poremba C, Lauterbach M, Wollenberg B, Buchberger AMS, Jesinghaus M, Schirmacher P, Stenzinger A, Weichert W, Boxberg M, Budczies J. Stögbauer F, et al. Br J Cancer. 2024 Feb;130(3):511. doi: 10.1038/s41416-023-02521-6. Br J Cancer. 2024. PMID: 38191610 Free PMC article. No abstract available.
Genomic heterogeneity at baseline is associated with T790M resistance mutations in EGFR-mutated lung cancer treated with the first-/second-generation tyrosine kinase inhibitors.
Menzel M, Kirchner M, Kluck K, Ball M, Beck S, Allgäuer M, Assmann C, Schnorbach J, Volckmar AL, Tay TKY, Goldschmid H, Tan DS, Thomas M, Kazdal D, Budczies J, Stenzinger A, Christopoulos P. Menzel M, et al. J Pathol Clin Res. 2024 Mar;10(2):e354. doi: 10.1002/cjp2.354. J Pathol Clin Res. 2024. PMID: 38284983 Free PMC article.
Tumour budding-based grading as independent prognostic biomarker in HPV-positive and HPV-negative head and neck cancer.
Stögbauer F, Beck S, Ourailidis I, Hess J, Poremba C, Lauterbach M, Wollenberg B, Buchberger AMS, Jesinghaus M, Schirmacher P, Stenzinger A, Weichert W, Boxberg M, Budczies J. Stögbauer F, et al. Br J Cancer. 2023 Jun;128(12):2295-2306. doi: 10.1038/s41416-023-02240-y. Epub 2023 Apr 12. Br J Cancer. 2023. PMID: 37045906 Free PMC article.
Genomic architecture of FGFR2 fusions in cholangiocarcinoma and its implication for molecular testing.
Neumann O, Burn TC, Allgäuer M, Ball M, Kirchner M, Albrecht T, Volckmar AL, Beck S, Endris V, Goldschmid H, Lehmann U, Seker-Cin H, Uhrig S, Roessler S, Budczies J, Fröhling S, Longerich T, Wagner AH, Vogel A, Schirmacher P, Stenzinger A, Kazdal D. Neumann O, et al. Br J Cancer. 2022 Nov;127(8):1540-1549. doi: 10.1038/s41416-022-01908-1. Epub 2022 Jul 23. Br J Cancer. 2022. PMID: 35871236 Free PMC article.
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