Law MC - Search Results

1

Characterization of a Potent, Selective, and Safe Inhibitor, Ac15(Az8)₂, in Reversing Multidrug Resistance Mediated by Breast Cancer Resistance Protein (BCRP/ABCG2).

Chong TC, Wong ILK, Cui J, Law MC, Zhu X, Hu X, Kan JWY, Yan CSW, Chan TH, Chow LMC. Chong TC, et al. Among authors: law mc. Int J Mol Sci. 2022 Oct 31;23(21):13261. doi: 10.3390/ijms232113261. Int J Mol Sci. 2022. PMID: 36362047 Free PMC article.

2

A New Class of Safe, Potent, and Specific P-gp Modulator: Flavonoid Dimer FD18 Reverses P-gp-Mediated Multidrug Resistance in Human Breast Xenograft in Vivo.

Yan CS, Wong IL, Chan KF, Kan JW, Chong TC, Law MC, Zhao Y, Chan SW, Chan TH, Chow LM. Yan CS, et al. Among authors: law mc. Mol Pharm. 2015 Oct 5;12(10):3507-17. doi: 10.1021/mp500770e. Epub 2015 Aug 27. Mol Pharm. 2015. PMID: 26291333

3

Discovery of Novel Flavonoid Dimers To Reverse Multidrug Resistance Protein 1 (MRP1, ABCC1) Mediated Drug Resistance in Cancers Using a High Throughput Platform with "Click Chemistry".

Wong ILK, Zhu X, Chan KF, Law MC, Lo AMY, Hu X, Chow LMC, Chan TH. Wong ILK, et al. Among authors: law mc. J Med Chem. 2018 Nov 21;61(22):9931-9951. doi: 10.1021/acs.jmedchem.8b00834. Epub 2018 Nov 1. J Med Chem. 2018. PMID: 30351934

4

Triazole Bridged Flavonoid Dimers as Potent, Nontoxic, and Highly Selective Breast Cancer Resistance Protein (BCRP/ABCG2) Inhibitors.

Zhu X, Wong ILK, Chan KF, Cui J, Law MC, Chong TC, Hu X, Chow LMC, Chan TH. Zhu X, et al. Among authors: law mc. J Med Chem. 2019 Sep 26;62(18):8578-8608. doi: 10.1021/acs.jmedchem.9b00963. Epub 2019 Sep 12. J Med Chem. 2019. PMID: 31465686

5

Flavonoid Monomers as Potent, Nontoxic, and Selective Modulators of the Breast Cancer Resistance Protein (ABCG2).

Wong ILK, Zhu X, Chan KF, Liu Z, Chan CF, Chow TS, Chong TC, Law MC, Cui J, Chow LMC, Chan TH. Wong ILK, et al. Among authors: law mc. J Med Chem. 2021 Oct 14;64(19):14311-14331. doi: 10.1021/acs.jmedchem.1c00779. Epub 2021 Oct 4. J Med Chem. 2021. PMID: 34606270

6

Formation and reactions of alkylzinc reagents in room-temperature ionic liquids.

Law MC, Wong KY, Chan TH. Law MC, et al. J Org Chem. 2005 Dec 9;70(25):10434-9. doi: 10.1021/jo051772m. J Org Chem. 2005. PMID: 16323854

7

Grignard reagents in ionic liquids.

Law MC, Wong KY, Chan TH. Law MC, et al. Chem Commun (Camb). 2006 Jun 21;(23):2457-9. doi: 10.1039/b602718k. Epub 2006 May 3. Chem Commun (Camb). 2006. PMID: 16758014

8

Development of a UPLC-MS/MS bioanalytical method for the pharmacokinetic study of (-)-epiafzelechin, a flavan-3-ol with osteoprotective activity, in C57BL/6J mice.

Wong KC, Law MC, Wong MS, Chan TH. Wong KC, et al. Among authors: law mc. J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Sep 15;967:162-7. doi: 10.1016/j.jchromb.2014.07.028. Epub 2014 Jul 27. J Chromatogr B Analyt Technol Biomed Life Sci. 2014. PMID: 25108364

9

Synthetic and mechanistic studies of indium-mediated allylation of imines in ionic liquids.

Law MC, Cheung TW, Wong KY, Chan TH. Law MC, et al. J Org Chem. 2007 Feb 2;72(3):923-9. doi: 10.1021/jo062198x. J Org Chem. 2007. PMID: 17253812

10

(-)-Epiafzelechin Protects against Ovariectomy-induced Bone Loss in Adult Mice and Modulate Osteoblastic and Osteoclastic Functions In Vitro.

Wong KC, Cao S, Dong X, Law MC, Chan TH, Wong MS. Wong KC, et al. Among authors: law mc. Nutrients. 2017 May 22;9(5):530. doi: 10.3390/nu9050530. Nutrients. 2017. PMID: 28531166 Free PMC article.

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