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Page 1
Human Neural Stem Cell-Based Drug Product: Clinical and Nonclinical Characterization.
Profico DC, Gelati M, Ferrari D, Sgaravizzi G, Ricciolini C, Projetti Pensi M, Muzi G, Cajola L, Copetti M, Ciusani E, Pugliese R, Gelain F, Vescovi AL. Profico DC, et al. Among authors: copetti m. Int J Mol Sci. 2022 Nov 3;23(21):13425. doi: 10.3390/ijms232113425. Int J Mol Sci. 2022. PMID: 36362211 Free PMC article.
The EphA2 receptor drives self-renewal and tumorigenicity in stem-like tumor-propagating cells from human glioblastomas.
Binda E, Visioli A, Giani F, Lamorte G, Copetti M, Pitter KL, Huse JT, Cajola L, Zanetti N, DiMeco F, De Filippis L, Mangiola A, Maira G, Anile C, De Bonis P, Reynolds BA, Pasquale EB, Vescovi AL. Binda E, et al. Among authors: copetti m. Cancer Cell. 2012 Dec 11;22(6):765-80. doi: 10.1016/j.ccr.2012.11.005. Cancer Cell. 2012. PMID: 23238013 Free PMC article.
Establishment of stable iPS-derived human neural stem cell lines suitable for cell therapies.
Rosati J, Ferrari D, Altieri F, Tardivo S, Ricciolini C, Fusilli C, Zalfa C, Profico DC, Pinos F, Bernardini L, Torres B, Manni I, Piaggio G, Binda E, Copetti M, Lamorte G, Mazza T, Carella M, Gelati M, Valente EM, Simeone A, Vescovi AL. Rosati J, et al. Among authors: copetti m. Cell Death Dis. 2018 Sep 17;9(10):937. doi: 10.1038/s41419-018-0990-2. Cell Death Dis. 2018. PMID: 30224709 Free PMC article.
Transplantation of clinical-grade human neural stem cells reduces neuroinflammation, prolongs survival and delays disease progression in the SOD1 rats.
Zalfa C, Rota Nodari L, Vacchi E, Gelati M, Profico D, Boido M, Binda E, De Filippis L, Copetti M, Garlatti V, Daniele P, Rosati J, De Luca A, Pinos F, Cajola L, Visioli A, Mazzini L, Vercelli A, Svelto M, Vescovi AL, Ferrari D. Zalfa C, et al. Among authors: copetti m. Cell Death Dis. 2019 Apr 25;10(5):345. doi: 10.1038/s41419-019-1582-5. Cell Death Dis. 2019. PMID: 31024007 Free PMC article.
Stemness underpinning all steps of human colorectal cancer defines the core of effective therapeutic strategies.
Visioli A, Giani F, Trivieri N, Pracella R, Miccinilli E, Cariglia MG, Palumbo O, Arleo A, Dezi F, Copetti M, Cajola L, Restelli S, Papa V, Sciuto A, Latiano TP, Carella M, Amadori D, Gallerani G, Ricci R, Alfieri S, Pesole G, Vescovi AL, Binda E. Visioli A, et al. Among authors: copetti m. EBioMedicine. 2019 Jun;44:346-360. doi: 10.1016/j.ebiom.2019.04.049. Epub 2019 May 2. EBioMedicine. 2019. PMID: 31056474 Free PMC article.
Results from Phase I Clinical Trial with Intraspinal Injection of Neural Stem Cells in Amyotrophic Lateral Sclerosis: A Long-Term Outcome.
Mazzini L, Gelati M, Profico DC, Sorarù G, Ferrari D, Copetti M, Muzi G, Ricciolini C, Carletti S, Giorgi C, Spera C, Frondizi D, Masiero S, Stecco A, Cisari C, Bersano E, De Marchi F, Sarnelli MF, Querin G, Cantello R, Petruzzelli F, Maglione A, Zalfa C, Binda E, Visioli A, Trombetta D, Torres B, Bernardini L, Gaiani A, Massara M, Paolucci S, Boulis NM, Vescovi AL; ALS-NSCs Trial Study Group. Mazzini L, et al. Among authors: copetti m. Stem Cells Transl Med. 2019 Sep;8(9):887-897. doi: 10.1002/sctm.18-0154. Epub 2019 May 18. Stem Cells Transl Med. 2019. PMID: 31104357 Free PMC article. Clinical Trial.
Growth factor independence underpins a paroxysmal, aggressive Wnt5aHigh/EphA2Low phenotype in glioblastoma stem cells, conducive to experimental combinatorial therapy.
Trivieri N, Visioli A, Mencarelli G, Cariglia MG, Marongiu L, Pracella R, Giani F, Soriano AA, Barile C, Cajola L, Copetti M, Palumbo O, Legnani F, DiMeco F, Gorgoglione L, Vescovi AL, Binda E. Trivieri N, et al. Among authors: copetti m. J Exp Clin Cancer Res. 2022 Apr 12;41(1):139. doi: 10.1186/s13046-022-02333-1. J Exp Clin Cancer Res. 2022. PMID: 35414102 Free PMC article.
Different states of stemness of glioblastoma stem cells sustain glioblastoma subtypes indicating novel clinical biomarkers and high-efficacy customized therapies.
Visioli A, Trivieri N, Mencarelli G, Giani F, Copetti M, Palumbo O, Pracella R, Cariglia MG, Barile C, Mischitelli L, Soriano AA, Palumbo P, Legnani F, DiMeco F, Gorgoglione L, Pesole G, Vescovi AL, Binda E. Visioli A, et al. Among authors: copetti m. J Exp Clin Cancer Res. 2023 Sep 21;42(1):244. doi: 10.1186/s13046-023-02811-0. J Exp Clin Cancer Res. 2023. PMID: 37735434 Free PMC article.
Phase I clinical trial of intracerebroventricular transplantation of allogeneic neural stem cells in people with progressive multiple sclerosis.
Leone MA, Gelati M, Profico DC, Gobbi C, Pravatà E, Copetti M, Conti C, Abate L, Amoruso L, Apollo F, Balzano RF, Bicchi I, Carella M, Ciampini A, Colosimo C, Crociani P, D'Aloisio G, Di Viesti P, Ferrari D, Fogli D, Fontana A, Frondizi D, Grespi V, Kuhle J, Laborante A, Lombardi I, Muzi G, Paci F, Placentino G, Popolizio T, Ricciolini C, Sabatini S, Silveri G, Spera C, Stephenson D, Stipa G, Tinella E, Zarrelli M, Zecca C, Ventura Y, D'Alessandro A, Peruzzotti-Jametti L, Pluchino S, Vescovi AL. Leone MA, et al. Among authors: copetti m. Cell Stem Cell. 2023 Dec 7;30(12):1597-1609.e8. doi: 10.1016/j.stem.2023.11.001. Epub 2023 Nov 27. Cell Stem Cell. 2023. PMID: 38016468 Free article. Clinical Trial.
359 results