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TREM2-independent microgliosis promotes tau-mediated neurodegeneration in the presence of ApoE4.
Gratuze M, Schlachetzki JCM, D'Oliveira Albanus R, Jain N, Novotny B, Brase L, Rodriguez L, Mansel C, Kipnis M, O'Brien S, Pasillas MP, Lee C, Manis M, Colonna M, Harari O, Glass CK, Ulrich JD, Holtzman DM. Gratuze M, et al. Among authors: colonna m. Neuron. 2023 Jan 18;111(2):202-219.e7. doi: 10.1016/j.neuron.2022.10.022. Epub 2022 Nov 10. Neuron. 2023. PMID: 36368315 Free PMC article.
TREM2 lipid sensing sustains the microglial response in an Alzheimer's disease model.
Wang Y, Cella M, Mallinson K, Ulrich JD, Young KL, Robinette ML, Gilfillan S, Krishnan GM, Sudhakar S, Zinselmeyer BH, Holtzman DM, Cirrito JR, Colonna M. Wang Y, et al. Among authors: colonna m. Cell. 2015 Mar 12;160(6):1061-71. doi: 10.1016/j.cell.2015.01.049. Epub 2015 Feb 26. Cell. 2015. PMID: 25728668 Free PMC article.
TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques.
Wang Y, Ulland TK, Ulrich JD, Song W, Tzaferis JA, Hole JT, Yuan P, Mahan TE, Shi Y, Gilfillan S, Cella M, Grutzendler J, DeMattos RB, Cirrito JR, Holtzman DM, Colonna M. Wang Y, et al. Among authors: colonna m. J Exp Med. 2016 May 2;213(5):667-75. doi: 10.1084/jem.20151948. Epub 2016 Apr 18. J Exp Med. 2016. PMID: 27091843 Free PMC article.
Elucidating the Role of TREM2 in Alzheimer's Disease.
Ulrich JD, Ulland TK, Colonna M, Holtzman DM. Ulrich JD, et al. Among authors: colonna m. Neuron. 2017 Apr 19;94(2):237-248. doi: 10.1016/j.neuron.2017.02.042. Neuron. 2017. PMID: 28426958 Free article. Review.
TREM2 Maintains Microglial Metabolic Fitness in Alzheimer's Disease.
Ulland TK, Song WM, Huang SC, Ulrich JD, Sergushichev A, Beatty WL, Loboda AA, Zhou Y, Cairns NJ, Kambal A, Loginicheva E, Gilfillan S, Cella M, Virgin HW, Unanue ER, Wang Y, Artyomov MN, Holtzman DM, Colonna M. Ulland TK, et al. Among authors: colonna m. Cell. 2017 Aug 10;170(4):649-663.e13. doi: 10.1016/j.cell.2017.07.023. Cell. 2017. PMID: 28802038 Free PMC article.
ApoE facilitates the microglial response to amyloid plaque pathology.
Ulrich JD, Ulland TK, Mahan TE, Nyström S, Nilsson KP, Song WM, Zhou Y, Reinartz M, Choi S, Jiang H, Stewart FR, Anderson E, Wang Y, Colonna M, Holtzman DM. Ulrich JD, et al. Among authors: colonna m. J Exp Med. 2018 Apr 2;215(4):1047-1058. doi: 10.1084/jem.20171265. Epub 2018 Feb 26. J Exp Med. 2018. PMID: 29483128 Free PMC article.
1,080 results