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TREM2-independent microgliosis promotes tau-mediated neurodegeneration in the presence of ApoE4.
Gratuze M, Schlachetzki JCM, D'Oliveira Albanus R, Jain N, Novotny B, Brase L, Rodriguez L, Mansel C, Kipnis M, O'Brien S, Pasillas MP, Lee C, Manis M, Colonna M, Harari O, Glass CK, Ulrich JD, Holtzman DM. Gratuze M, et al. Neuron. 2023 Jan 18;111(2):202-219.e7. doi: 10.1016/j.neuron.2022.10.022. Epub 2022 Nov 10. Neuron. 2023. PMID: 36368315 Free PMC article.
Insulin dysfunction and Tau pathology.
El Khoury NB, Gratuze M, Papon MA, Bretteville A, Planel E. El Khoury NB, et al. Among authors: gratuze m. Front Cell Neurosci. 2014 Feb 11;8:22. doi: 10.3389/fncel.2014.00022. eCollection 2014. Front Cell Neurosci. 2014. PMID: 24574966 Free PMC article. Review.
TREM2 function impedes tau seeding in neuritic plaques.
Leyns CEG, Gratuze M, Narasimhan S, Jain N, Koscal LJ, Jiang H, Manis M, Colonna M, Lee VMY, Ulrich JD, Holtzman DM. Leyns CEG, et al. Among authors: gratuze m. Nat Neurosci. 2019 Aug;22(8):1217-1222. doi: 10.1038/s41593-019-0433-0. Epub 2019 Jun 24. Nat Neurosci. 2019. PMID: 31235932 Free PMC article.
SEQUIN Multiscale Imaging of Mammalian Central Synapses Reveals Loss of Synaptic Connectivity Resulting from Diffuse Traumatic Brain Injury.
Sauerbeck AD, Gangolli M, Reitz SJ, Salyards MH, Kim SH, Hemingway C, Gratuze M, Makkapati T, Kerschensteiner M, Holtzman DM, Brody DL, Kummer TT. Sauerbeck AD, et al. Among authors: gratuze m. Neuron. 2020 Jul 22;107(2):257-273.e5. doi: 10.1016/j.neuron.2020.04.012. Epub 2020 May 8. Neuron. 2020. PMID: 32392471 Free PMC article.
40 results