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Molecular glue CELMoD compounds are regulators of cereblon conformation.
Watson ER, Novick S, Matyskiela ME, Chamberlain PP, H de la Peña A, Zhu J, Tran E, Griffin PR, Wertz IE, Lander GC. Watson ER, et al. Among authors: griffin pr. Science. 2022 Nov 4;378(6619):549-553. doi: 10.1126/science.add7574. Epub 2022 Nov 3. Science. 2022. PMID: 36378961 Free PMC article.
HDX workbench: software for the analysis of H/D exchange MS data.
Pascal BD, Willis S, Lauer JL, Landgraf RR, West GM, Marciano D, Novick S, Goswami D, Chalmers MJ, Griffin PR. Pascal BD, et al. Among authors: griffin pr. J Am Soc Mass Spectrom. 2012 Sep;23(9):1512-21. doi: 10.1007/s13361-012-0419-6. Epub 2012 Jun 13. J Am Soc Mass Spectrom. 2012. PMID: 22692830 Free PMC article.
Nitric oxide-induced conformational changes in soluble guanylate cyclase.
Underbakke ES, Iavarone AT, Chalmers MJ, Pascal BD, Novick S, Griffin PR, Marletta MA. Underbakke ES, et al. Among authors: griffin pr. Structure. 2014 Apr 8;22(4):602-11. doi: 10.1016/j.str.2014.01.008. Epub 2014 Feb 20. Structure. 2014. PMID: 24560804 Free PMC article.
Pharmacological repression of PPARγ promotes osteogenesis.
Marciano DP, Kuruvilla DS, Boregowda SV, Asteian A, Hughes TS, Garcia-Ordonez R, Corzo CA, Khan TM, Novick SJ, Park H, Kojetin DJ, Phinney DG, Bruning JB, Kamenecka TM, Griffin PR. Marciano DP, et al. Among authors: griffin pr. Nat Commun. 2015 Jun 12;6:7443. doi: 10.1038/ncomms8443. Nat Commun. 2015. PMID: 26068133 Free PMC article.
Synthetic RORγt Agonists Enhance Protective Immunity.
Chang MR, Dharmarajan V, Doebelin C, Garcia-Ordonez RD, Novick SJ, Kuruvilla DS, Kamenecka TM, Griffin PR. Chang MR, et al. Among authors: griffin pr. ACS Chem Biol. 2016 Apr 15;11(4):1012-8. doi: 10.1021/acschembio.5b00899. Epub 2016 Jan 25. ACS Chem Biol. 2016. PMID: 26785144 Free PMC article.
Estrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation.
Fanning SW, Mayne CG, Dharmarajan V, Carlson KE, Martin TA, Novick SJ, Toy W, Green B, Panchamukhi S, Katzenellenbogen BS, Tajkhorshid E, Griffin PR, Shen Y, Chandarlapaty S, Katzenellenbogen JA, Greene GL. Fanning SW, et al. Among authors: griffin pr. Elife. 2016 Feb 2;5:e12792. doi: 10.7554/eLife.12792. Elife. 2016. PMID: 26836308 Free PMC article.
284 results