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Co-transducing B7H3 CAR-NK cells with the DNR preserves their cytolytic function against GBM in the presence of exogenous TGF-β.
Chaudhry K, Geiger A, Dowlati E, Lang H, Sohai DK, Hwang EI, Lazarski CA, Yvon E, Holdhoff M, Jones R, Savoldo B, Cruz CRY, Bollard CM. Chaudhry K, et al. Among authors: geiger a. Mol Ther Methods Clin Dev. 2022 Oct 21;27:415-430. doi: 10.1016/j.omtm.2022.10.010. eCollection 2022 Dec 8. Mol Ther Methods Clin Dev. 2022. PMID: 36381305 Free PMC article.
Comparable transforming growth factor beta-mediated immune suppression in ex vivo-expanded natural killer cells from cord blood and peripheral blood: implications for adoptive immunotherapy.
Chaudhry K, Dowlati E, Long MD, Geiger A, Lang H, Gomez EC, Muniraj N, Sanchez CE, Singh PK, Liu S, Bollard CM, Cruz CRY. Chaudhry K, et al. Among authors: geiger a. Cytotherapy. 2022 Aug;24(8):802-817. doi: 10.1016/j.jcyt.2022.04.001. Epub 2022 May 17. Cytotherapy. 2022. PMID: 35589475 Free PMC article.
SARS-CoV-2-specific T cells are rapidly expanded for therapeutic use and target conserved regions of the membrane protein.
Keller MD, Harris KM, Jensen-Wachspress MA, Kankate VV, Lang H, Lazarski CA, Durkee-Shock J, Lee PH, Chaudhry K, Webber K, Datar A, Terpilowski M, Reynolds EK, Stevenson EM, Val S, Shancer Z, Zhang N, Ulrey R, Ekanem U, Stanojevic M, Geiger A, Liang H, Hoq F, Abraham AA, Hanley PJ, Cruz CR, Ferrer K, Dropulic L, Gangler K, Burbelo PD, Jones RB, Cohen JI, Bollard CM. Keller MD, et al. Among authors: geiger a. Blood. 2020 Dec 17;136(25):2905-2917. doi: 10.1182/blood.2020008488. Blood. 2020. PMID: 33331927 Free PMC article.
Identification of novel HLA-restricted preferentially expressed antigen in melanoma peptides to facilitate off-the-shelf tumor-associated antigen-specific T-cell therapies.
Stanojevic M, Hont AB, Geiger A, O'Brien S, Ulrey R, Grant M, Datar A, Lee PH, Lang H, Cruz CRY, Hanley PJ, Barrett AJ, Keller MD, Bollard CM. Stanojevic M, et al. Among authors: geiger a. Cytotherapy. 2021 Aug;23(8):694-703. doi: 10.1016/j.jcyt.2021.03.001. Epub 2021 Apr 5. Cytotherapy. 2021. PMID: 33832817 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 33104167
498 results