Reggio PH - Search Results

1

Pharmacological evaluation of enantiomerically separated positive allosteric modulators of cannabinoid 1 receptor, GAT591 and GAT593.

Brandt AL, Garai S, Zagzoog A, Hurst DP, Stevenson LA, Pertwee RG, Imler GH, Reggio PH, Thakur GA, Laprairie RB. Brandt AL, et al. Among authors: reggio ph. Front Pharmacol. 2022 Oct 25;13:919605. doi: 10.3389/fphar.2022.919605. eCollection 2022. Front Pharmacol. 2022. PMID: 36386195 Free PMC article.

2

The design, synthesis and testing of desoxy-CBD: further evidence for a region of steric interference at the cannabinoid receptor.

Reggio PH, Bramblett RD, Yuknavich H, Seltzman HH, Fleming DN, Fernando SR, Stevenson LA, Pertwee RG. Reggio PH, et al. Life Sci. 1995;56(23-24):2025-32. doi: 10.1016/0024-3205(95)00185-9. Life Sci. 1995. PMID: 7776828

3

The bioactive conformation of aminoalkylindoles at the cannabinoid CB1 and CB2 receptors: insights gained from (E)- and (Z)-naphthylidene indenes.

Reggio PH, Basu-Dutt S, Barnett-Norris J, Castro MT, Hurst DP, Seltzman HH, Roche MJ, Gilliam AF, Thomas BF, Stevenson LA, Pertwee RG, Abood ME. Reggio PH, et al. J Med Chem. 1998 Dec 17;41(26):5177-87. doi: 10.1021/jm9801197. J Med Chem. 1998. PMID: 9857088

4

Role of a conserved lysine residue in the peripheral cannabinoid receptor (CB2): evidence for subtype specificity.

Tao Q, McAllister SD, Andreassi J, Nowell KW, Cabral GA, Hurst DP, Bachtel K, Ekman MC, Reggio PH, Abood ME. Tao Q, et al. Among authors: reggio ph. Mol Pharmacol. 1999 Mar;55(3):605-13. Mol Pharmacol. 1999. PMID: 10051546

5

The difference between the CB(1) and CB(2) cannabinoid receptors at position 5.46 is crucial for the selectivity of WIN55212-2 for CB(2).

Song ZH, Slowey CA, Hurst DP, Reggio PH. Song ZH, et al. Among authors: reggio ph. Mol Pharmacol. 1999 Oct;56(4):834-40. Mol Pharmacol. 1999. PMID: 10496968

6

A critical role for a tyrosine residue in the cannabinoid receptors for ligand recognition.

McAllister SD, Tao Q, Barnett-Norris J, Buehner K, Hurst DP, Guarnieri F, Reggio PH, Nowell Harmon KW, Cabral GA, Abood ME. McAllister SD, et al. Among authors: reggio ph. Biochem Pharmacol. 2002 Jun 15;63(12):2121-36. doi: 10.1016/s0006-2952(02)01031-6. Biochem Pharmacol. 2002. PMID: 12110371

7

Conformational memories and the endocannabinoid binding site at the cannabinoid CB1 receptor.

Barnett-Norris J, Hurst DP, Lynch DL, Guarnieri F, Makriyannis A, Reggio PH. Barnett-Norris J, et al. Among authors: reggio ph. J Med Chem. 2002 Aug 15;45(17):3649-59. doi: 10.1021/jm0200761. J Med Chem. 2002. PMID: 12166938

8

N-(piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716A) interaction with LYS 3.28(192) is crucial for its inverse agonism at the cannabinoid CB1 receptor.

Hurst DP, Lynch DL, Barnett-Norris J, Hyatt SM, Seltzman HH, Zhong M, Song ZH, Nie J, Lewis D, Reggio PH. Hurst DP, et al. Among authors: reggio ph. Mol Pharmacol. 2002 Dec;62(6):1274-87. doi: 10.1124/mol.62.6.1274. Mol Pharmacol. 2002. PMID: 12435794

9

Cysteine 2.59(89) in the second transmembrane domain of human CB2 receptor is accessible within the ligand binding crevice: evidence for possible CB2 deviation from a rhodopsin template.

Zhang R, Hurst DP, Barnett-Norris J, Reggio PH, Song ZH. Zhang R, et al. Among authors: reggio ph. Mol Pharmacol. 2005 Jul;68(1):69-83. doi: 10.1124/mol.104.007823. Epub 2005 Apr 19. Mol Pharmacol. 2005. PMID: 15840841

10

Adamantyl cannabinoids: a novel class of cannabinergic ligands.

Lu D, Meng Z, Thakur GA, Fan P, Steed J, Tartal CL, Hurst DP, Reggio PH, Deschamps JR, Parrish DA, George C, Järbe TU, Lamb RJ, Makriyannis A. Lu D, et al. Among authors: reggio ph. J Med Chem. 2005 Jul 14;48(14):4576-85. doi: 10.1021/jm058175c. J Med Chem. 2005. PMID: 15999995

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