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273 results

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Page 1
C3G transgenic mouse models with specific expression in platelets reveal a new role for C3G in platelet clotting through its GEF activity.
Gutiérrez-Herrero S, Maia V, Gutiérrez-Berzal J, Calzada N, Sanz M, González-Manchón C, Pericacho M, Ortiz-Rivero S, González-Porras JR, Arechederra M, Porras A, Guerrero C. Gutiérrez-Herrero S, et al. Among authors: porras a. Biochim Biophys Acta. 2012 Aug;1823(8):1366-77. doi: 10.1016/j.bbamcr.2012.05.021. Epub 2012 May 29. Biochim Biophys Acta. 2012. PMID: 22659131 Free article.
C3G forms complexes with Bcr-Abl and p38α MAPK at the focal adhesions in chronic myeloid leukemia cells: implication in the regulation of leukemic cell adhesion.
Maia V, Ortiz-Rivero S, Sanz M, Gutierrez-Berzal J, Alvarez-Fernández I, Gutierrez-Herrero S, de Pereda JM, Porras A, Guerrero C. Maia V, et al. Among authors: porras a. Cell Commun Signal. 2013 Jan 23;11(1):9. doi: 10.1186/1478-811X-11-9. Cell Commun Signal. 2013. PMID: 23343344 Free PMC article.
Met signaling in cardiomyocytes is required for normal cardiac function in adult mice.
Arechederra M, Carmona R, González-Nuñez M, Gutiérrez-Uzquiza A, Bragado P, Cruz-González I, Cano E, Guerrero C, Sánchez A, López-Novoa JM, Schneider MD, Maina F, Muñoz-Chápuli R, Porras A. Arechederra M, et al. Among authors: porras a. Biochim Biophys Acta. 2013 Dec;1832(12):2204-15. doi: 10.1016/j.bbadis.2013.08.008. Epub 2013 Aug 28. Biochim Biophys Acta. 2013. PMID: 23994610 Free article.
p38 MAPK down-regulates fibulin 3 expression through methylation of gene regulatory sequences: role in migration and invasion.
Arechederra M, Priego N, Vázquez-Carballo A, Sequera C, Gutiérrez-Uzquiza Á, Cerezo-Guisado MI, Ortiz-Rivero S, Roncero C, Cuenda A, Guerrero C, Porras A. Arechederra M, et al. Among authors: porras a. J Biol Chem. 2015 Feb 13;290(7):4383-97. doi: 10.1074/jbc.M114.582239. Epub 2014 Dec 29. J Biol Chem. 2015. PMID: 25548290 Free PMC article.
C3G knock-down enhances migration and invasion by increasing Rap1-mediated p38α activation, while it impairs tumor growth through p38α-independent mechanisms.
Priego N, Arechederra M, Sequera C, Bragado P, Vázquez-Carballo A, Gutiérrez-Uzquiza Á, Martín-Granado V, Ventura JJ, Kazanietz MG, Guerrero C, Porras A. Priego N, et al. Among authors: porras a. Oncotarget. 2016 Jul 19;7(29):45060-45078. doi: 10.18632/oncotarget.9911. Oncotarget. 2016. PMID: 27286263 Free PMC article.
C3G promotes a selective release of angiogenic factors from activated mouse platelets to regulate angiogenesis and tumor metastasis.
Martín-Granado V, Ortiz-Rivero S, Carmona R, Gutiérrez-Herrero S, Barrera M, San-Segundo L, Sequera C, Perdiguero P, Lozano F, Martín-Herrero F, González-Porras JR, Muñoz-Chápuli R, Porras A, Guerrero C. Martín-Granado V, et al. Among authors: porras a. Oncotarget. 2017 Nov 6;8(67):110994-111011. doi: 10.18632/oncotarget.22339. eCollection 2017 Dec 19. Oncotarget. 2017. PMID: 29340032 Free PMC article.
273 results