Discovery of Brain-Penetrant Glucosylceramide Synthase Inhibitors with a Novel Pharmacophore.
Tanaka Y, Seto M, Kakegawa K, Takami K, Kikuchi F, Yamamoto T, Nakamura M, Daini M, Murakami M, Ohashi T, Kasahara T, Wang J, Ikeda Z, Wada Y, Puenner F, Fujii T, Inazuka M, Sato S, Suzaki T, Oak JH, Takai Y, Kohara H, Kimoto K, Oki H, Mikami S, Sasaki M, Tanaka Y.
Tanaka Y, et al. Among authors: takai y.
J Med Chem. 2022 Mar 10;65(5):4270-4290. doi: 10.1021/acs.jmedchem.1c02078. Epub 2022 Feb 21.
J Med Chem. 2022.
PMID: 35188773
Free article.