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EROS is a selective chaperone regulating the phagocyte NADPH oxidase and purinergic signalling.
Randzavola LO, Mortimer PM, Garside E, Dufficy ER, Schejtman A, Roumelioti G, Yu L, Pardo M, Spirohn K, Tolley C, Brandt C, Harcourt K, Nichols E, Nahorski M, Woods G, Williamson JC, Suresh S, Sowerby JM, Matsumoto M, Santos CXC, Kiar CS, Mukhopadhyay S, Rae WM, Dougan GJ, Grainger J, Lehner PJ, Calderwood MA, Choudhary J, Clare S, Speak A, Santilli G, Bateman A, Smith KGC, Magnani F, Thomas DC. Randzavola LO, et al. Among authors: nichols e. Elife. 2022 Nov 24;11:e76387. doi: 10.7554/eLife.76387. Elife. 2022. PMID: 36421765 Free PMC article.
A novel mutation in EROS (CYBC1) causes chronic granulomatous disease.
Mortimer PM, Nichols E, Thomas J, Shanbhag R, Singh N, Coomber EL, Malik TH, Pickering MC, Randzavola L, Rae W, Bhattad S, Thomas DC. Mortimer PM, et al. Among authors: nichols e. Clin Immunol. 2023 Oct;255:109761. doi: 10.1016/j.clim.2023.109761. Epub 2023 Sep 8. Clin Immunol. 2023. PMID: 37673227
563 results