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Moonlighting chaperone activity of the enzyme PqsE contributes to RhlR-controlled virulence of Pseudomonas aeruginosa.
Borgert SR, Henke S, Witzgall F, Schmelz S, Zur Lage S, Hotop SK, Stephen S, Lübken D, Krüger J, Gomez NO, van Ham M, Jänsch L, Kalesse M, Pich A, Brönstrup M, Häussler S, Blankenfeldt W. Borgert SR, et al. Among authors: schmelz s. Nat Commun. 2022 Dec 1;13(1):7402. doi: 10.1038/s41467-022-35030-w. Nat Commun. 2022. PMID: 36456567 Free PMC article.
The Scottish Structural Proteomics Facility: targets, methods and outputs.
Oke M, Carter LG, Johnson KA, Liu H, McMahon SA, Yan X, Kerou M, Weikart ND, Kadi N, Sheikh MA, Schmelz S, Dorward M, Zawadzki M, Cozens C, Falconer H, Powers H, Overton IM, van Niekerk CA, Peng X, Patel P, Garrett RA, Prangishvili D, Botting CH, Coote PJ, Dryden DT, Barton GJ, Schwarz-Linek U, Challis GL, Taylor GL, White MF, Naismith JH. Oke M, et al. Among authors: schmelz s. J Struct Funct Genomics. 2010 Jun;11(2):167-80. doi: 10.1007/s10969-010-9090-y. Epub 2010 Apr 24. J Struct Funct Genomics. 2010. PMID: 20419351 Free PMC article.
In situ structural analysis of the Yersinia enterocolitica injectisome.
Kudryashev M, Stenta M, Schmelz S, Amstutz M, Wiesand U, Castaño-Díez D, Degiacomi MT, Münnich S, Bleck CK, Kowal J, Diepold A, Heinz DW, Dal Peraro M, Cornelis GR, Stahlberg H. Kudryashev M, et al. Among authors: schmelz s. Elife. 2013 Jul 30;2:e00792. doi: 10.7554/eLife.00792. Elife. 2013. PMID: 23908767 Free PMC article.
Adenylate-forming enzymes.
Schmelz S, Naismith JH. Schmelz S, et al. Curr Opin Struct Biol. 2009 Dec;19(6):666-71. doi: 10.1016/j.sbi.2009.09.004. Curr Opin Struct Biol. 2009. PMID: 19836944 Free PMC article. Review.
Braces for the peptide backbone: insights into structure-activity relationships of protease inhibitor mimics with locked amide conformations.
Tischler M, Nasu D, Empting M, Schmelz S, Heinz DW, Rottmann P, Kolmar H, Buntkowsky G, Tietze D, Avrutina O. Tischler M, et al. Among authors: schmelz s. Angew Chem Int Ed Engl. 2012 Apr 10;51(15):3708-12. doi: 10.1002/anie.201108983. Epub 2012 Feb 28. Angew Chem Int Ed Engl. 2012. PMID: 22374650 No abstract available.
A New PqsR Inverse Agonist Potentiates Tobramycin Efficacy to Eradicate Pseudomonas aeruginosa Biofilms.
Schütz C, Ho DK, Hamed MM, Abdelsamie AS, Röhrig T, Herr C, Kany AM, Rox K, Schmelz S, Siebenbürger L, Wirth M, Börger C, Yahiaoui S, Bals R, Scrima A, Blankenfeldt W, Horstmann JC, Christmann R, Murgia X, Koch M, Berwanger A, Loretz B, Hirsch AKH, Hartmann RW, Lehr CM, Empting M. Schütz C, et al. Among authors: schmelz s. Adv Sci (Weinh). 2021 Jun;8(12):e2004369. doi: 10.1002/advs.202004369. Epub 2021 Mar 18. Adv Sci (Weinh). 2021. PMID: 34165899 Free PMC article.
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