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Page 1
Improved PIEZO1 agonism through 4-benzoic acid modification of Yoda1.
Parsonage G, Cuthbertson K, Endesh N, Murciano N, Hyman AJ, Revill CH, Povstyan OV, Chuntharpursat-Bon E, Debant M, Ludlow MJ, Futers TS, Lichtenstein L, Kinsella JA, Bartoli F, Rotordam MG, Becker N, Brüggemann A, Foster R, Beech DJ. Parsonage G, et al. Among authors: debant m. Br J Pharmacol. 2023 Aug;180(16):2039-2063. doi: 10.1111/bph.15996. Epub 2023 Jan 31. Br J Pharmacol. 2023. PMID: 36457143 Free PMC article.
Endothelial Piezo1 sustains muscle capillary density and contributes to physical activity.
Bartoli F, Debant M, Chuntharpursat-Bon E, Evans EL, Musialowski KE, Parsonage G, Morley LC, Futers TS, Sukumar P, Bowen TS, Kearney MT, Lichtenstein L, Roberts LD, Beech DJ. Bartoli F, et al. Among authors: debant m. J Clin Invest. 2022 Mar 1;132(5):e141775. doi: 10.1172/JCI141775. J Clin Invest. 2022. PMID: 35025768 Free PMC article.
Orai1 Channel Inhibition Preserves Left Ventricular Systolic Function and Normal Ca2+ Handling After Pressure Overload.
Bartoli F, Bailey MA, Rode B, Mateo P, Antigny F, Bedouet K, Gerbaud P, Gosain R, Plante J, Norman K, Gomez S, Lefebvre F, Rucker-Martin C, Ainscough JFX, Kearney MT, Bruns AF, Shi J, Appleby HL, Young RS, Shawer HM, Debant M, Gomez AM, Beech DJ, Foster R, Benitah JP, Sabourin J. Bartoli F, et al. Among authors: debant m. Circulation. 2020 Jan 21;141(3):199-216. doi: 10.1161/CIRCULATIONAHA.118.038891. Epub 2020 Jan 7. Circulation. 2020. PMID: 31906693 Free PMC article.
Pharmacology of PIEZO1 channels.
Kinsella JA, Debant M, Parsonage G, Morley LC, Bajarwan M, Revill C, Foster R, Beech DJ. Kinsella JA, et al. Among authors: debant m. Br J Pharmacol. 2024 Dec;181(23):4714-4732. doi: 10.1111/bph.17351. Epub 2024 Oct 14. Br J Pharmacol. 2024. PMID: 39402010 Review.
PIEZO1 and PECAM1 interact at cell-cell junctions and partner in endothelial force sensing.
Chuntharpursat-Bon E, Povstyan OV, Ludlow MJ, Carrier DJ, Debant M, Shi J, Gaunt HJ, Bauer CC, Curd A, Simon Futers T, Baxter PD, Peckham M, Muench SP, Adamson A, Humphreys N, Tumova S, Bon RS, Cubbon R, Lichtenstein L, Beech DJ. Chuntharpursat-Bon E, et al. Among authors: debant m. Commun Biol. 2023 Apr 1;6(1):358. doi: 10.1038/s42003-023-04706-4. Commun Biol. 2023. PMID: 37005489 Free PMC article.
Cx43 Present at the Leading Edge Membrane Governs Promigratory Effects of Osteoblast-Conditioned Medium on Human Prostate Cancer Cells in the Context of Bone Metastasis.
Boucher J, Balandre AC, Debant M, Vix J, Harnois T, Bourmeyster N, Péraudeau E, Chépied A, Clarhaut J, Debiais F, Monvoisin A, Cronier L. Boucher J, et al. Among authors: debant m. Cancers (Basel). 2020 Oct 16;12(10):3013. doi: 10.3390/cancers12103013. Cancers (Basel). 2020. PMID: 33081404 Free PMC article.
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