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Retrotransposon instability dominates the acquired mutation landscape of mouse induced pluripotent stem cells.
Gerdes P, Lim SM, Ewing AD, Larcombe MR, Chan D, Sanchez-Luque FJ, Walker L, Carleton AL, James C, Knaupp AS, Carreira PE, Nefzger CM, Lister R, Richardson SR, Polo JM, Faulkner GJ. Gerdes P, et al. Among authors: sanchez luque fj. Nat Commun. 2022 Dec 3;13(1):7470. doi: 10.1038/s41467-022-35180-x. Nat Commun. 2022. PMID: 36463236 Free PMC article.
Ubiquitous L1 mosaicism in hippocampal neurons.
Upton KR, Gerhardt DJ, Jesuadian JS, Richardson SR, Sánchez-Luque FJ, Bodea GO, Ewing AD, Salvador-Palomeque C, van der Knaap MS, Brennan PM, Vanderver A, Faulkner GJ. Upton KR, et al. Cell. 2015 Apr 9;161(2):228-39. doi: 10.1016/j.cell.2015.03.026. Cell. 2015. PMID: 25860606 Free PMC article.
Heritable L1 retrotransposition in the mouse primordial germline and early embryo.
Richardson SR, Gerdes P, Gerhardt DJ, Sanchez-Luque FJ, Bodea GO, Muñoz-Lopez M, Jesuadian JS, Kempen MHC, Carreira PE, Jeddeloh JA, Garcia-Perez JL, Kazazian HH Jr, Ewing AD, Faulkner GJ. Richardson SR, et al. Genome Res. 2017 Aug;27(8):1395-1405. doi: 10.1101/gr.219022.116. Epub 2017 May 8. Genome Res. 2017. PMID: 28483779 Free PMC article.
L1 retrotransposition is a common feature of mammalian hepatocarcinogenesis.
Schauer SN, Carreira PE, Shukla R, Gerhardt DJ, Gerdes P, Sanchez-Luque FJ, Nicoli P, Kindlova M, Ghisletti S, Santos AD, Rapoud D, Samuel D, Faivre J, Ewing AD, Richardson SR, Faulkner GJ. Schauer SN, et al. Genome Res. 2018 May;28(5):639-653. doi: 10.1101/gr.226993.117. Epub 2018 Apr 11. Genome Res. 2018. PMID: 29643204 Free PMC article.
30 results