Zhu J - Search Results

1

Tuberculosis treatment failure associated with evolution of antibiotic resilience.

Liu Q, Zhu J, Dulberger CL, Stanley S, Wilson S, Chung ES, Wang X, Culviner P, Liu YJ, Hicks ND, Babunovic GH, Giffen SR, Aldridge BB, Garner EC, Rubin EJ, Chao MC, Fortune SM. Liu Q, et al. Among authors: zhu j. Science. 2022 Dec 9;378(6624):1111-1118. doi: 10.1126/science.abq2787. Epub 2022 Dec 8. Science. 2022. PMID: 36480634 Free PMC article.

2

Kasugamycin potentiates rifampicin and limits emergence of resistance in Mycobacterium tuberculosis by specifically decreasing mycobacterial mistranslation.

Chaudhuri S, Li L, Zimmerman M, Chen Y, Chen YX, Toosky MN, Gardner M, Pan M, Li YY, Kawaji Q, Zhu JH, Su HW, Martinot AJ, Rubin EJ, Dartois VA, Javid B. Chaudhuri S, et al. Among authors: zhu jh. Elife. 2018 Aug 28;7:e36782. doi: 10.7554/eLife.36782. Elife. 2018. PMID: 30152756 Free PMC article.

3

Itaconyl-CoA forms a stable biradical in methylmalonyl-CoA mutase and derails its activity and repair.

Ruetz M, Campanello GC, Purchal M, Shen H, McDevitt L, Gouda H, Wakabayashi S, Zhu J, Rubin EJ, Warncke K, Mootha VK, Koutmos M, Banerjee R. Ruetz M, et al. Among authors: zhu j. Science. 2019 Nov 1;366(6465):589-593. doi: 10.1126/science.aay0934. Science. 2019. PMID: 31672889 Free PMC article.

4

Pyrazinamide triggers degradation of its target aspartate decarboxylase.

Gopal P, Sarathy JP, Yee M, Ragunathan P, Shin J, Bhushan S, Zhu J, Akopian T, Kandror O, Lim TK, Gengenbacher M, Lin Q, Rubin EJ, Grüber G, Dick T. Gopal P, et al. Among authors: zhu j. Nat Commun. 2020 Apr 3;11(1):1661. doi: 10.1038/s41467-020-15516-1. Nat Commun. 2020. PMID: 32245967 Free PMC article.

5

Clinically relevant mutations in mycobacterial LepA cause rifampicin-specific phenotypic resistance.

Wang BW, Zhu JH, Javid B. Wang BW, et al. Sci Rep. 2020 May 21;10(1):8402. doi: 10.1038/s41598-020-65308-2. Sci Rep. 2020. PMID: 32439911 Free PMC article.

6

ClpX Is Essential and Activated by Single-Strand DNA Binding Protein in Mycobacteria.

Kester JC, Kandror O, Akopian T, Chase MR, Zhu J, Rubin EJ, Goldberg AL, Fortune SM. Kester JC, et al. Among authors: zhu j. J Bacteriol. 2021 Jan 25;203(4):e00608-20. doi: 10.1128/JB.00608-20. Print 2021 Jan 25. J Bacteriol. 2021. PMID: 33229461 Free PMC article.

7

A Mycobacterial Systems Resource for the Research Community.

Judd JA, Canestrari J, Clark R, Joseph A, Lapierre P, Lasek-Nesselquist E, Mir M, Palumbo M, Smith C, Stone M, Upadhyay A, Wirth SE, Dedrick RM, Meier CG, Russell DA, Dills A, Dove E, Kester J, Wolf ID, Zhu J, Rubin ER, Fortune S, Hatfull GF, Gray TA, Wade JT, Derbyshire KM. Judd JA, et al. Among authors: zhu j. mBio. 2021 Mar 2;12(2):e02401-20. doi: 10.1128/mBio.02401-20. mBio. 2021. PMID: 33653882 Free PMC article.

8

6-Fluorophenylbenzohydrazides inhibit Mycobacterium tuberculosis growth through alteration of tryptophan biosynthesis.

Consalvi S, Venditti G, Zhu J, Boshoff HI, Arora K, De Logu A, Ioerger TR, Rubin EJ, Biava M, Poce G. Consalvi S, et al. Among authors: zhu j. Eur J Med Chem. 2021 Dec 15;226:113843. doi: 10.1016/j.ejmech.2021.113843. Epub 2021 Sep 9. Eur J Med Chem. 2021. PMID: 34520959 Free PMC article.

9

Spatiotemporal localization of proteins in mycobacteria.

Zhu J, Wolf ID, Dulberger CL, Won HI, Kester JC, Judd JA, Wirth SE, Clark RR, Li Y, Luo Y, Gray TA, Wade JT, Derbyshire KM, Fortune SM, Rubin EJ. Zhu J, et al. Cell Rep. 2021 Dec 28;37(13):110154. doi: 10.1016/j.celrep.2021.110154. Cell Rep. 2021. PMID: 34965429 Free PMC article.

10

Transposon mutagenesis in Mycobacterium abscessus identifies an essential penicillin-binding protein involved in septal peptidoglycan synthesis and antibiotic sensitivity.

Akusobi C, Benghomari BS, Zhu J, Wolf ID, Singhvi S, Dulberger CL, Ioerger TR, Rubin EJ. Akusobi C, et al. Among authors: zhu j. Elife. 2022 Jun 6;11:e71947. doi: 10.7554/eLife.71947. Elife. 2022. PMID: 35659317 Free PMC article.

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