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Page 1
SARS-CoV-2 Spike triggers barrier dysfunction and vascular leak via integrins and TGF-β signaling.
Biering SB, Gomes de Sousa FT, Tjang LV, Pahmeier F, Zhu C, Ruan R, Blanc SF, Patel TS, Worthington CM, Glasner DR, Castillo-Rojas B, Servellita V, Lo NTN, Wong MP, Warnes CM, Sandoval DR, Clausen TM, Santos YA, Fox DM, Ortega V, Näär AM, Baric RS, Stanley SA, Aguilar HC, Esko JD, Chiu CY, Pak JE, Beatty PR, Harris E. Biering SB, et al. Among authors: lo ntn. Nat Commun. 2022 Dec 9;13(1):7630. doi: 10.1038/s41467-022-34910-5. Nat Commun. 2022. PMID: 36494335 Free PMC article.
Endocytosis of flavivirus NS1 is required for NS1-mediated endothelial hyperpermeability and is abolished by a single N-glycosylation site mutation.
Wang C, Puerta-Guardo H, Biering SB, Glasner DR, Tran EB, Patana M, Gomberg TA, Malvar C, Lo NTN, Espinosa DA, Harris E. Wang C, et al. Among authors: lo ntn. PLoS Pathog. 2019 Jul 29;15(7):e1007938. doi: 10.1371/journal.ppat.1007938. eCollection 2019 Jul. PLoS Pathog. 2019. PMID: 31356638 Free PMC article.
Structural basis for antibody inhibition of flavivirus NS1-triggered endothelial dysfunction.
Biering SB, Akey DL, Wong MP, Brown WC, Lo NTN, Puerta-Guardo H, Tramontini Gomes de Sousa F, Wang C, Konwerski JR, Espinosa DA, Bockhaus NJ, Glasner DR, Li J, Blanc SF, Juan EY, Elledge SJ, Mina MJ, Beatty PR, Smith JL, Harris E. Biering SB, et al. Among authors: lo ntn. Science. 2021 Jan 8;371(6525):194-200. doi: 10.1126/science.abc0476. Science. 2021. PMID: 33414220 Free PMC article.
SARS-CoV-2 Spike triggers barrier dysfunction and vascular leak via integrins and TGF-β signaling.
Biering SB, de Sousa FTG, Tjang LV, Pahmeier F, Ruan R, Blanc SF, Patel TS, Worthington CM, Glasner DR, Castillo-Rojas B, Servellita V, Lo NTN, Wong MP, Warnes CM, Sandoval DR, Clausen TM, Santos YA, Ortega V, Aguilar HC, Esko JD, Chui CY, Pak JE, Beatty PR, Harris E. Biering SB, et al. Among authors: lo ntn. bioRxiv [Preprint]. 2021 Dec 13:2021.12.10.472112. doi: 10.1101/2021.12.10.472112. bioRxiv. 2021. Update in: Nat Commun. 2022 Dec 9;13(1):7630. doi: 10.1038/s41467-022-34910-5 PMID: 34931188 Free PMC article. Updated. Preprint.