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Page 1
The origins and molecular evolution of SARS-CoV-2 lineage B.1.1.7 in the UK.
Hill V, Du Plessis L, Peacock TP, Aggarwal D, Colquhoun R, Carabelli AM, Ellaby N, Gallagher E, Groves N, Jackson B, McCrone JT, O'Toole Á, Price A, Sanderson T, Scher E, Southgate J, Volz E, Barclay WS, Barrett JC, Chand M, Connor T, Goodfellow I, Gupta RK, Harrison EM, Loman N, Myers R, Robertson DL, Pybus OG, Rambaut A. Hill V, et al. Among authors: gupta rk. Virus Evol. 2022 Aug 26;8(2):veac080. doi: 10.1093/ve/veac080. eCollection 2022. Virus Evol. 2022. PMID: 36533153 Free PMC article.
Selection analysis identifies unusual clustered mutational changes in Omicron lineage BA.1 that likely impact Spike function.
Martin DP, Lytras S, Lucaci AG, Maier W, Grüning B, Shank SD, Weaver S, MacLean OA, Orton RJ, Lemey P, Boni MF, Tegally H, Harkins G, Scheepers C, Bhiman JN, Everatt J, Amoako DG, San JE, Giandhari J, Sigal A; NGS-SA; Williamson C, Hsiao NY, von Gottberg A, De Klerk A, Shafer RW, Robertson DL, Wilkinson RJ, Sewell BT, Lessells R, Nekrutenko A, Greaney AJ, Starr TN, Bloom JD, Murrell B, Wilkinson E, Gupta RK, de Oliveira T, Kosakovsky Pond SL. Martin DP, et al. Among authors: gupta rk. bioRxiv [Preprint]. 2022 Jan 18:2022.01.14.476382. doi: 10.1101/2022.01.14.476382. bioRxiv. 2022. Update in: Mol Biol Evol. 2022 Apr 11;39(4):msac061. doi: 10.1093/molbev/msac061 PMID: 35075456 Free PMC article. Updated. Preprint.
SARS-CoV-2 variant evasion of monoclonal antibodies based on in vitro studies.
Cox M, Peacock TP, Harvey WT, Hughes J, Wright DW; COVID-19 Genomics UK (COG-UK) Consortium; Willett BJ, Thomson E, Gupta RK, Peacock SJ, Robertson DL, Carabelli AM. Cox M, et al. Among authors: gupta rk. Nat Rev Microbiol. 2023 Feb;21(2):112-124. doi: 10.1038/s41579-022-00809-7. Epub 2022 Oct 28. Nat Rev Microbiol. 2023. PMID: 36307535 Free PMC article. Review.
Point of Care Nucleic Acid Testing for SARS-CoV-2 in Hospitalized Patients: A Clinical Validation Trial and Implementation Study.
Collier DA, Assennato SM, Warne B, Sithole N, Sharrocks K, Ritchie A, Ravji P, Routledge M, Sparkes D, Skittrall J, Smielewska A, Ramsey I, Goel N, Curran M, Enoch D, Tassell R, Lineham M, Vaghela D, Leong C, Mok HP, Bradley J, Smith KGC, Mendoza V, Demiris N, Besser M, Dougan G, Lehner PJ, Siedner MJ, Zhang H, Waddington CS, Lee H, Gupta RK; CITIID-NIHR COVID BioResource Collaboration. Collier DA, et al. Among authors: gupta rk. Cell Rep Med. 2020 Aug 25;1(5):100062. doi: 10.1016/j.xcrm.2020.100062. Epub 2020 Jul 15. Cell Rep Med. 2020. PMID: 32838340 Free PMC article. Clinical Trial.
Atypical B cells and impaired SARS-CoV-2 neutralization following heterologous vaccination in the elderly.
Ferreira IATM, Lee CYC, Foster WS, Abdullahi A, Dratva LM, Tuong ZK, Stewart BJ, Ferdinand JR, Guillaume SM, Potts MOP, Perera M, Krishna BA, Peñalver A, Cabantous M, Kemp SA, Ceron-Gutierrez L, Ebrahimi S; CITIID-NIHR BioResource COVID-19 Collaboration; Lyons P, Smith KGC, Bradley J, Collier DA, McCoy LE, van der Klaauw A, Thaventhiran JED, Farooqi IS, Teichmann SA, MacAry PA, Doffinger R, Wills MR, Linterman MA, Clatworthy MR, Gupta RK. Ferreira IATM, et al. Among authors: gupta rk. Cell Rep. 2023 Aug 29;42(8):112991. doi: 10.1016/j.celrep.2023.112991. Epub 2023 Aug 16. Cell Rep. 2023. PMID: 37590132 Free article.
Limited emergence of resistance to integrase strand transfer inhibitors (INSTIs) in ART-experienced participants failing dolutegravir-based antiretroviral therapy: a cross-sectional analysis of a Northeast Nigerian cohort.
Abdullahi A, Kida IM, Maina UA, Ibrahim AH, Mshelia J, Wisso H, Adamu A, Onyemata JE, Edun M, Yusuph H, Aliyu SH, Charurat M, Abimiku A, Abeler-Dorner L, Fraser C, Bonsall D; PANGEA consortium; Kemp SA, Gupta RK. Abdullahi A, et al. Among authors: gupta rk. J Antimicrob Chemother. 2023 Aug 2;78(8):2000-2007. doi: 10.1093/jac/dkad195. J Antimicrob Chemother. 2023. PMID: 37367727 Free PMC article.
The IRE1α-XBP1 arm of the unfolded protein response is a host factor activated in SARS-CoV-2 infection.
Fernández JJ, Marín A, Rosales R, Penrice-Randal R, Mlcochova P, Alvarez Y, Villalón-Letelier F, Yildiz S, Pérez E, Rathnasinghe R, Cupic A, Kehrer T, Uccellini MB, Alonso S, Martínez F, McGovern BL, Clark JJ, Sharma P, Bayón Y, Alonso A, Albrecht RA, White KM, Schotsaert M, Miorin L, Stewart JP, Hiscox JA, Gupta RK, Irigoyen N, García-Sastre A, Crespo MS, Fernández N. Fernández JJ, et al. Among authors: gupta rk. Biochim Biophys Acta Mol Basis Dis. 2024 Jun;1870(5):167193. doi: 10.1016/j.bbadis.2024.167193. Epub 2024 Apr 20. Biochim Biophys Acta Mol Basis Dis. 2024. PMID: 38648902
Defining neutralization and allostery by antibodies against COVID-19 variants.
Tulsian NK, Palur RV, Qian X, Gu Y, D/O Shunmuganathan B, Samsudin F, Wong YH, Lin J, Purushotorman K, Kozma MM, Wang B, Lescar J, Wang CI, Gupta RK, Bond PJ, MacAry PA. Tulsian NK, et al. Among authors: gupta rk. Nat Commun. 2023 Nov 1;14(1):6967. doi: 10.1038/s41467-023-42408-x. Nat Commun. 2023. PMID: 37907459 Free PMC article.
2,804 results