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High titre neutralizing antibodies in response to SARS-CoV-2 infection require RBD-specific CD4 T cells that include proliferative memory cells.
Phetsouphanh C, Khoo WH, Jackson K, Klemm V, Howe A, Aggarwal A, Akerman A, Milogiannakis V, Stella AO, Rouet R, Schofield P, Faulks ML, Law H, Danwilai T, Starr M, Munier CML, Christ D, Singh M, Croucher PI, Brilot-Turville F, Turville S, Phan TG, Dore GJ, Darley D, Cunningham P, Matthews GV, Kelleher AD, Zaunders JJ. Phetsouphanh C, et al. Among authors: akerman a. Front Immunol. 2022 Dec 5;13:1032911. doi: 10.3389/fimmu.2022.1032911. eCollection 2022. Front Immunol. 2022. PMID: 36544780 Free PMC article.
COVID-19 vaccine failure in chronic lymphocytic leukaemia and monoclonal B-lymphocytosis; humoural and cellular immunity.
Shen Y, Freeman JA, Holland J, Solterbeck A, Naidu K, Soosapilla A, Downe P, Tang C, Kerridge I, Wallman L, Van Bilsen N, Milogiannakis V, Akerman A, Martins Costa Gomes G, Sandgren K, Cunningham AL, Turville S, Mulligan SP. Shen Y, et al. Among authors: akerman a. Br J Haematol. 2022 Apr;197(1):41-51. doi: 10.1111/bjh.18014. Epub 2022 Jan 5. Br J Haematol. 2022. PMID: 34962656
Platform for isolation and characterization of SARS-CoV-2 variants enables rapid characterization of Omicron in Australia.
Aggarwal A, Stella AO, Walker G, Akerman A, Esneau C, Milogiannakis V, Burnett DL, McAllery S, Silva MR, Lu Y, Foster CSP, Brilot F, Pillay A, Van Hal S, Mathivanan V, Fichter C, Kindinger A, Hoppe AC, Munier ML, Amatayakul-Chantler S, Roth N, Coppola G, Symonds GP, Schofield P, Jackson J, Lenthall H, Henry JY, Mazigi O, Jäck HM, Davenport MP, Darley DR, Matthews GV, Khoury DS, Cromer D, Goodnow CC, Christ D, Robosa R, Starck DJ, Bartlett NW, Rawlinson WD, Kelleher AD, Turville SG. Aggarwal A, et al. Among authors: akerman a. Nat Microbiol. 2022 Jun;7(6):896-908. doi: 10.1038/s41564-022-01135-7. Epub 2022 May 30. Nat Microbiol. 2022. PMID: 35637329 Free PMC article.
SARS-CoV-2 Omicron BA.5: Evolving tropism and evasion of potent humoral responses and resistance to clinical immunotherapeutics relative to viral variants of concern.
Aggarwal A, Akerman A, Milogiannakis V, Silva MR, Walker G, Stella AO, Kindinger A, Angelovich T, Waring E, Amatayakul-Chantler S, Roth N, Manni S, Hauser T, Barnes T, Condylios A, Yeang M, Wong M, Jean T, Foster CSP, Christ D, Hoppe AC, Munier ML, Darley D, Churchill M, Stark DJ, Matthews G, Rawlinson WD, Kelleher AD, Turville SG. Aggarwal A, et al. Among authors: akerman a. EBioMedicine. 2022 Oct;84:104270. doi: 10.1016/j.ebiom.2022.104270. Epub 2022 Sep 18. EBioMedicine. 2022. PMID: 36130476 Free PMC article.
Multiple COVID-19 vaccine doses in CLL and MBL improve immune responses with progressive and high seroconversion.
Shen Y, Freeman JA, Holland J, Naidu K, Solterbeck A, Van Bilsen N, Downe P, Kerridge I, Wallman L, Akerman A, Aggarwal A, Milogiannakis V, Martins Costa Gomes G, Doyle CM, Sandgren KJ, Turville S, Cunningham AL, Mulligan SP. Shen Y, et al. Among authors: akerman a. Blood. 2022 Dec 22;140(25):2709-2721. doi: 10.1182/blood.2022017814. Blood. 2022. PMID: 36206503 Free PMC article.
Emergence and antibody evasion of BQ, BA.2.75 and SARS-CoV-2 recombinant sub-lineages in the face of maturing antibody breadth at the population level.
Akerman A, Milogiannakis V, Jean T, Esneau C, Silva MR, Ison T, Fichter C, Lopez JA, Chandra D, Naing Z, Caguicla J, Li D, Walker G, Amatayakul-Chantler S, Roth N, Manni S, Hauser T, Barnes T, Condylios A, Yeang M, Wong M, Foster CSP, Sato K, Lee S, Song Y, Mao L, Sigmund A, Phu A, Vande More AM, Hunt S, Douglas M, Caterson I, Britton W, Sandgren K, Bull R, Lloyd A, Triccas J, Tangye S, Bartlett NW, Darley D, Matthews G, Stark DJ, Petoumenos K, Rawlinson WD, Murrell B, Brilot F, Cunningham AL, Kelleher AD, Aggarwal A, Turville SG. Akerman A, et al. EBioMedicine. 2023 Apr;90:104545. doi: 10.1016/j.ebiom.2023.104545. Epub 2023 Mar 30. EBioMedicine. 2023. PMID: 37002990 Free PMC article.
Humoral and cellular immunity to SARS-CoV-2 Ancestral and Omicron BA.5 variants following vaccination in myelofibrosis patients.
Alcheikh A, Perkins GB, Pucar PA, Cecchin A, Chai CS, Tunbridge M, Akerman A, Aggarwal A, Milogiannakis V, Turville S, Allen S, Hissaria P, Banovic T, Coates PT, Ross DM. Alcheikh A, et al. Among authors: akerman a. Blood Cancer J. 2023 Apr 10;13(1):50. doi: 10.1038/s41408-023-00824-8. Blood Cancer J. 2023. PMID: 37032391 Free PMC article. No abstract available.
Enhanced stability of the SARS CoV-2 spike glycoprotein following modification of an alanine cavity in the protein core.
Poumbourios P, Langer C, Boo I, Zakir T, Center RJ, Akerman A, Milogiannakis V, Aggarwal A, Johnstone BA, Ha J, Coulibaly F, Turville SG, Drummer HE. Poumbourios P, et al. Among authors: akerman a. PLoS Pathog. 2023 May 18;19(5):e1010981. doi: 10.1371/journal.ppat.1010981. eCollection 2023 May. PLoS Pathog. 2023. PMID: 37200378 Free PMC article.
Novel siRNA therapeutics demonstrate multi-variant efficacy against SARS-CoV-2.
Bowden-Reid E, Ledger S, Zhang Y, Di Giallonardo F, Aggarwal A, Stella AO, Akerman A, Milogiannakis V, Walker G, Rawlinson W, Turville S, Kelleher AD, Ahlenstiel C. Bowden-Reid E, et al. Among authors: akerman a. Antiviral Res. 2023 Sep;217:105677. doi: 10.1016/j.antiviral.2023.105677. Epub 2023 Jul 20. Antiviral Res. 2023. PMID: 37478918 Free article.
122 results