Wong LW - Search Results

1

Hydroxychloroquine lowers Alzheimer's disease and related dementias risk and rescues molecular phenotypes related to Alzheimer's disease.

Varma VR, Desai RJ, Navakkode S, Wong LW, Anerillas C, Loeffler T, Schilcher I, Mahesri M, Chin K, Horton DB, Kim SC, Gerhard T, Segal JB, Schneeweiss S, Gorospe M, Sajikumar S, Thambisetty M. Varma VR, et al. Among authors: wong lw. Mol Psychiatry. 2023 Mar;28(3):1312-1326. doi: 10.1038/s41380-022-01912-0. Epub 2022 Dec 28. Mol Psychiatry. 2023. PMID: 36577843 Free PMC article.

2

Abnormal TDP-43 function impairs activity-dependent BDNF secretion, synaptic plasticity, and cognitive behavior through altered Sortilin splicing.

Tann JY, Wong LW, Sajikumar S, Ibáñez CF. Tann JY, et al. Among authors: wong lw. EMBO J. 2019 Mar 1;38(5):e100989. doi: 10.15252/embj.2018100989. Epub 2019 Jan 28. EMBO J. 2019. PMID: 30692134 Free PMC article.

3

The p75 Neurotrophin Receptor Is an Essential Mediator of Impairments in Hippocampal-Dependent Associative Plasticity and Memory Induced by Sleep Deprivation.

Wong LW, Tann JY, Ibanez CF, Sajikumar S. Wong LW, et al. J Neurosci. 2019 Jul 10;39(28):5452-5465. doi: 10.1523/JNEUROSCI.2876-18.2019. Epub 2019 May 13. J Neurosci. 2019. PMID: 31085607 Free PMC article.

4

Deletion of CD137 Ligand Exacerbates Renal and Cutaneous but Alleviates Cerebral Manifestations in Lupus.

Mak A, Dharmadhikari B, Kow NY, Thamboo TP, Tang Q, Wong LW, Sajikumar S, Wong HY, Schwarz H. Mak A, et al. Among authors: wong lw, wong hy. Front Immunol. 2019 Jun 26;10:1411. doi: 10.3389/fimmu.2019.01411. eCollection 2019. Front Immunol. 2019. PMID: 31297111 Free PMC article.

5

Inhibition of Histone Deacetylase Reinstates Hippocampus-Dependent Long-Term Synaptic Plasticity and Associative Memory in Sleep-Deprived Mice.

Wong LW, Chong YS, Wong WLE, Sajikumar S. Wong LW, et al. Among authors: wong wle. Cereb Cortex. 2020 Jun 1;30(7):4169-4182. doi: 10.1093/cercor/bhaa041. Cereb Cortex. 2020. PMID: 32188968

6

Inactive variants of death receptor p75^NTR reduce Alzheimer's neuropathology by interfering with APP internalization.

Yi C, Goh KY, Wong LW, Ramanujan A, Tanaka K, Sajikumar S, Ibáñez CF. Yi C, et al. Among authors: wong lw. EMBO J. 2021 Jan 15;40(2):e104450. doi: 10.15252/embj.2020104450. Epub 2020 Dec 1. EMBO J. 2021. PMID: 33258176 Free PMC article.

7

Wong LW, Chong YS, Lin W, Kisiswa L, Sim E, Ibáñez CF, Sajikumar S. Wong LW, et al. Aging Cell. 2021 Feb;20(2):e13305. doi: 10.1111/acel.13305. Epub 2021 Jan 15. Aging Cell. 2021. PMID: 33448137 Free PMC article.

8

Fading memories in aging and neurodegeneration: Is p75 neurotrophin receptor a culprit?

Wong LW, Wang Z, Ang SRX, Sajikumar S. Wong LW, et al. Ageing Res Rev. 2022 Mar;75:101567. doi: 10.1016/j.arr.2022.101567. Epub 2022 Jan 17. Ageing Res Rev. 2022. PMID: 35051645 Review.

9

Distinct contributions of ventral CA1/amygdala co-activation to the induction and maintenance of synaptic plasticity.

Chong YS, Wong LW, Gaunt J, Lee YJ, Goh CS, Morris RGM, Ch'ng TH, Sajikumar S. Chong YS, et al. Among authors: wong lw. Cereb Cortex. 2023 Jan 5;33(3):676-690. doi: 10.1093/cercor/bhac093. Cereb Cortex. 2023. PMID: 35253866

10

Inhibition of Nogo-A rescues synaptic plasticity and associativity in APP/PS1 animal model of Alzheimer's disease.

Pavon MV, Navakkode S, Wong LW, Sajikumar S. Pavon MV, et al. Among authors: wong lw. Semin Cell Dev Biol. 2023 Apr;139:111-120. doi: 10.1016/j.semcdb.2022.04.005. Epub 2022 Apr 14. Semin Cell Dev Biol. 2023. PMID: 35431138

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