Beale GS - Search Results

1

Sulfatase-2 from Cancer Associated Fibroblasts: An Environmental Target for Hepatocellular Carcinoma?

Zaki MYW, Alhasan SF, Shukla R, McCain M, Laszczewska M, Geh D, Patman GL, Televantou D, Whitehead A, Maurício JP, Barksby B, Gee LM, Paish HL, Leslie J, Younes R, Burt AD, Borthwick LA, Thomas H, Beale GS, Govaere O, Sia D, Anstee QM, Tiniakos D, Oakley F, Reeves HL. Zaki MYW, et al. Among authors: beale gs. Liver Cancer. 2022 Jul 13;11(6):540-557. doi: 10.1159/000525375. eCollection 2022 Dec. Liver Cancer. 2022. PMID: 36589727 Free PMC article.

2

Sulfatase-2: a prognostic biomarker and candidate therapeutic target in patients with pancreatic ductal adenocarcinoma.

Alhasan SF, Haugk B, Ogle LF, Beale GS, Long A, Burt AD, Tiniakos D, Televantou D, Coxon F, Newell DR, Charnley R, Reeves HL. Alhasan SF, et al. Among authors: beale gs. Br J Cancer. 2016 Sep 27;115(7):797-804. doi: 10.1038/bjc.2016.264. Epub 2016 Aug 25. Br J Cancer. 2016. PMID: 27560551 Free PMC article.

3

A proteomic strategy to identify novel serum biomarkers for liver cirrhosis and hepatocellular cancer in individuals with fatty liver disease.

Gray J, Chattopadhyay D, Beale GS, Patman GL, Miele L, King BP, Stewart S, Hudson M, Day CP, Manas DM, Reeves HL. Gray J, et al. Among authors: beale gs. BMC Cancer. 2009 Aug 5;9:271. doi: 10.1186/1471-2407-9-271. BMC Cancer. 2009. PMID: 19656391 Free PMC article.

4

Regioselective sulfamoylation at low temperature enables concise syntheses of putative small molecule inhibitors of sulfatases.

Miller DC, Carbain B, Beale GS, Alhasan SF, Reeves HL, Baisch U, Newell DR, Golding BT, Griffin RJ. Miller DC, et al. Among authors: beale gs. Org Biomol Chem. 2015 May 14;13(18):5279-84. doi: 10.1039/c5ob00211g. Org Biomol Chem. 2015. PMID: 25858034

5

The Kruppel-like factor 6 genotype is associated with fibrosis in nonalcoholic fatty liver disease.

Miele L, Beale G, Patman G, Nobili V, Leathart J, Grieco A, Abate M, Friedman SL, Narla G, Bugianesi E, Day CP, Reeves HL. Miele L, et al. Gastroenterology. 2008 Jul;135(1):282-291.e1. doi: 10.1053/j.gastro.2008.04.004. Epub 2008 Apr 11. Gastroenterology. 2008. PMID: 18515091 Free PMC article.

6

AFP, PIVKAII, GP3, SCCA-1 and follisatin as surveillance biomarkers for hepatocellular cancer in non-alcoholic and alcoholic fatty liver disease.

Beale G, Chattopadhyay D, Gray J, Stewart S, Hudson M, Day C, Trerotoli P, Giannelli G, Manas D, Reeves H. Beale G, et al. BMC Cancer. 2008 Jul 18;8:200. doi: 10.1186/1471-2407-8-200. BMC Cancer. 2008. PMID: 18638391 Free PMC article.

7

Design and synthesis of biphenyl and biphenyl ether inhibitors of sulfatases.

Reuillon T, Alhasan SF, Beale GS, Bertoli A, Brennan A, Cano C, Reeves HL, Newell DR, Golding BT, Miller DC, Griffin RJ. Reuillon T, et al. Among authors: beale gs. Chem Sci. 2016 Apr 21;7(4):2821-2826. doi: 10.1039/c5sc03612g. Epub 2016 Jan 11. Chem Sci. 2016. PMID: 28660059 Free PMC article.

8

Combined PI3K and CDK2 inhibition induces cell death and enhances in vivo antitumour activity in colorectal cancer.

Beale G, Haagensen EJ, Thomas HD, Wang LZ, Revill CH, Payne SL, Golding BT, Hardcastle IR, Newell DR, Griffin RJ, Cano C. Beale G, et al. Br J Cancer. 2016 Sep 6;115(6):682-90. doi: 10.1038/bjc.2016.238. Epub 2016 Aug 16. Br J Cancer. 2016. PMID: 27529512 Free PMC article.

9

Identification and evaluation of a potent novel ATR inhibitor, NU6027, in breast and ovarian cancer cell lines.

Peasland A, Wang LZ, Rowling E, Kyle S, Chen T, Hopkins A, Cliby WA, Sarkaria J, Beale G, Edmondson RJ, Curtin NJ. Peasland A, et al. Br J Cancer. 2011 Jul 26;105(3):372-81. doi: 10.1038/bjc.2011.243. Epub 2011 Jul 5. Br J Cancer. 2011. PMID: 21730979 Free PMC article.

10

The synergistic interaction of MEK and PI3K inhibitors is modulated by mTOR inhibition.

Haagensen EJ, Kyle S, Beale GS, Maxwell RJ, Newell DR. Haagensen EJ, et al. Among authors: beale gs. Br J Cancer. 2012 Apr 10;106(8):1386-94. doi: 10.1038/bjc.2012.70. Epub 2012 Mar 13. Br J Cancer. 2012. PMID: 22415236 Free PMC article.

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