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The scaffold RhoGAP protein ARHGAP8/BPGAP1 synchronizes Rac and Rho signaling to facilitate cell migration.
Wong DCP, Pan CQ, Er SY, Thivakar T, Rachel TZY, Seah SH, Chua PJ, Jiang T, Chew TW, Chaudhuri PK, Mukherjee S, Salim A, Aye TA, Koh CG, Lim CT, Tan PH, Bay BH, Ridley AJ, Low BC. Wong DCP, et al. Among authors: ridley aj. Mol Biol Cell. 2023 Mar 1;34(3):ar13. doi: 10.1091/mbc.E21-03-0099. Epub 2023 Jan 4. Mol Biol Cell. 2023. PMID: 36598812 Free PMC article.
Statins change the cytokine profile in Trypanosoma cruzi-infected U937 macrophages and murine cardiac tissue through Rho-associated kinases inhibition.
González-Herrera F, Clayton NS, Guzmán-Rivera D, Carrillo I, Castillo C, Catalán M, Anfossi R, Quintero-Pertuz H, Quilaqueo ME, Olea-Azar C, Rivera-Meza M, Kemmerling U, Ridley AJ, Vivar R, Maya JD. González-Herrera F, et al. Among authors: ridley aj. Front Immunol. 2023 Jan 11;13:1035589. doi: 10.3389/fimmu.2022.1035589. eCollection 2022. Front Immunol. 2023. PMID: 36713380 Free PMC article.
Pharmacological inhibition of ezrin reduces proliferative and invasive phenotype in acute lymphoblastic leukemia cells.
Lipreri da Silva JC, Lima K, Ede B, Lazarini M, Vicari HP, Nogueira FL, Clayton NS, Pinnell K, Silva WFD, Velloso EDRP, Bendit I, Costa-Lotufo LV, Rego EM, Ridley AJ, Machado-Neto JA. Lipreri da Silva JC, et al. Among authors: ridley aj. Eur J Pharmacol. 2024 Nov 29;987:177161. doi: 10.1016/j.ejphar.2024.177161. Online ahead of print. Eur J Pharmacol. 2024. PMID: 39615869
RhoU forms homo-oligomers to regulate cellular responses.
Clayton NS, Hodge RG, Infante E, Alibhai D, Zhou F, Ridley AJ. Clayton NS, et al. Among authors: ridley aj. J Cell Sci. 2024 Jan 15;137(2):jcs261645. doi: 10.1242/jcs.261645. Epub 2024 Jan 30. J Cell Sci. 2024. PMID: 38180080 Free PMC article.
230 results