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Page 1
DWORF Extends Life Span in a PLN-R14del Cardiomyopathy Mouse Model by Reducing Abnormal Sarcoplasmic Reticulum Clusters.
Stege NM, Eijgenraam TR, Oliveira Nunes Teixeira V, Feringa AM, Schouten EM, Kuster DWD, van der Velden J, Wolters AHG, Giepmans BNG, Makarewich CA, Bassel-Duby R, Olson EN, de Boer RA, Silljé HHW. Stege NM, et al. Among authors: eijgenraam tr. Circ Res. 2023 Dec 8;133(12):1006-1021. doi: 10.1161/CIRCRESAHA.123.323304. Epub 2023 Nov 13. Circ Res. 2023. PMID: 37955153 Free PMC article.
Associations of relative fat mass, a new index of adiposity, with type-2 diabetes in the general population.
Suthahar N, Wang K, Zwartkruis VW, Bakker SJL, Inzucchi SE, Meems LMG, Eijgenraam TR, Ahmadizar F, Sijbrands EG, Gansevoort RT, Kieneker LM, van Veldhuisen DJ, Kavousi M, de Boer RA. Suthahar N, et al. Among authors: eijgenraam tr. Eur J Intern Med. 2023 Mar;109:73-78. doi: 10.1016/j.ejim.2022.12.024. Epub 2023 Jan 4. Eur J Intern Med. 2023. PMID: 36604231 Free article.
Multi-omics analyses identify molecular signatures with prognostic values in different heart failure aetiologies.
Aboumsallem JP, Shi C, De Wit S, Markousis-Mavrogenis G, Bracun V, Eijgenraam TR, Hoes MF, Meijers WC, Screever EM, Schouten ME, Voors AA, Silljé HHW, De Boer RA. Aboumsallem JP, et al. Among authors: eijgenraam tr. J Mol Cell Cardiol. 2023 Feb;175:13-28. doi: 10.1016/j.yjmcc.2022.12.001. Epub 2022 Dec 6. J Mol Cell Cardiol. 2023. PMID: 36493852 Free article.
Antisense Therapy Attenuates Phospholamban p.(Arg14del) Cardiomyopathy in Mice and Reverses Protein Aggregation.
Eijgenraam TR, Stege NM, Oliveira Nunes Teixeira V, de Brouwer R, Schouten EM, Grote Beverborg N, Sun L, Später D, Knöll R, Hansson KM, Amilon C, Janzén D, Yeh ST, Mullick AE, van der Meer P, de Boer RA, Silljé HHW. Eijgenraam TR, et al. Int J Mol Sci. 2022 Feb 22;23(5):2427. doi: 10.3390/ijms23052427. Int J Mol Sci. 2022. PMID: 35269571 Free PMC article.
Protein Aggregation Is an Early Manifestation of Phospholamban p.(Arg14del)-Related Cardiomyopathy: Development of PLN-R14del-Related Cardiomyopathy.
Eijgenraam TR, Boogerd CJ, Stege NM, Oliveira Nunes Teixeira V, Dokter MM, Schmidt LE, Yin X, Theofilatos K, Mayr M, van der Meer P, van Rooij E, van der Velden J, Silljé HHW, de Boer RA. Eijgenraam TR, et al. Circ Heart Fail. 2021 Nov;14(11):e008532. doi: 10.1161/CIRCHEARTFAILURE.121.008532. Epub 2021 Sep 30. Circ Heart Fail. 2021. PMID: 34587756 Free PMC article.
Phospholamban antisense oligonucleotides improve cardiac function in murine cardiomyopathy.
Grote Beverborg N, Später D, Knöll R, Hidalgo A, Yeh ST, Elbeck Z, Silljé HHW, Eijgenraam TR, Siga H, Zurek M, Palmér M, Pehrsson S, Albery T, Bomer N, Hoes MF, Boogerd CJ, Frisk M, van Rooij E, Damle S, Louch WE, Wang QD, Fritsche-Danielson R, Chien KR, Hansson KM, Mullick AE, de Boer RA, van der Meer P. Grote Beverborg N, et al. Among authors: eijgenraam tr. Nat Commun. 2021 Aug 30;12(1):5180. doi: 10.1038/s41467-021-25439-0. Nat Commun. 2021. PMID: 34462437 Free PMC article.
Author Correction: The phospholamban p.(Arg14del) pathogenic variant leads to cardiomyopathy with heart failure and is unresponsive to standard heart failure therapy.
Eijgenraam TR, Boukens BJ, Boogerd CJ, Schouten EM, van de Kolk CWA, Stege NM, Te Rijdt WP, Hoorntje ET, van der Zwaag PA, van Rooij E, van Tintelen JP, van den Berg MP, van der Meer P, van der Velden J, Silljé HHW, de Boer RA. Eijgenraam TR, et al. Sci Rep. 2020 Oct 2;10(1):16710. doi: 10.1038/s41598-020-70780-x. Sci Rep. 2020. PMID: 33009422 Free PMC article.
Strength of patient cohorts and biobanks for cardiomyopathy research.
de Boer RA, Nijenkamp LLAM, Silljé HHW, Eijgenraam TR, Parbhudayal R, van Driel B, Huurman R, Michels M, Pei J, Harakalova M, van Lint FHM, Jansen M, Baas AF, Asselbergs FW, van Tintelen JP, Brundel BJJM, Dorsch LM, Schuldt M, Kuster DWD, van der Velden J; DOSIS consortium. de Boer RA, et al. Among authors: eijgenraam tr. Neth Heart J. 2020 Aug;28(Suppl 1):50-56. doi: 10.1007/s12471-020-01456-4. Neth Heart J. 2020. PMID: 32780332 Free PMC article. Review.
The phospholamban p.(Arg14del) pathogenic variant leads to cardiomyopathy with heart failure and is unreponsive to standard heart failure therapy.
Eijgenraam TR, Boukens BJ, Boogerd CJ, Schouten EM, van de Kolk CWA, Stege NM, Te Rijdt WP, Hoorntje ET, van der Zwaag PA, van Rooij E, van Tintelen JP, van den Berg MP, van der Meer P, van der Velden J, Silljé HHW, de Boer RA. Eijgenraam TR, et al. Sci Rep. 2020 Jun 17;10(1):9819. doi: 10.1038/s41598-020-66656-9. Sci Rep. 2020. PMID: 32555305 Free PMC article.
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