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Page 1
Single-cell transcriptomics reveals a mechanosensitive injury signaling pathway in early diabetic nephropathy.
Liu S, Zhao Y, Lu S, Zhang T, Lindenmeyer MT, Nair V, Gies SE, Wu G, Nelson RG, Czogalla J, Aypek H, Zielinski S, Liao Z, Schaper M, Fermin D, Cohen CD, Delic D, Krebs CF, Grahammer F, Wiech T, Kretzler M, Meyer-Schwesinger C, Bonn S, Huber TB. Liu S, et al. Among authors: zhao y. Genome Med. 2023 Jan 10;15(1):2. doi: 10.1186/s13073-022-01145-4. Genome Med. 2023. PMID: 36627643 Free PMC article.
Pathogen-induced tissue-resident memory TH17 (TRM17) cells amplify autoimmune kidney disease.
Krebs CF, Reimers D, Zhao Y, Paust HJ, Bartsch P, Nuñez S, Rosemblatt MV, Hellmig M, Kilian C, Borchers A, Enk LUB, Zinke M, Becker M, Schmid J, Klinge S, Wong MN, Puelles VG, Schmidt C, Bertram T, Stumpf N, Hoxha E, Meyer-Schwesinger C, Lindenmeyer MT, Cohen CD, Rink M, Kurts C, Franzenburg S, Koch-Nolte F, Turner JE, Riedel JH, Huber S, Gagliani N, Huber TB, Wiech T, Rohde H, Bono MR, Bonn S, Panzer U, Mittrücker HW. Krebs CF, et al. Among authors: zhao y. Sci Immunol. 2020 Aug 7;5(50):eaba4163. doi: 10.1126/sciimmunol.aba4163. Sci Immunol. 2020. PMID: 32769171
Clonal expansion and activation of tissue-resident memory-like Th17 cells expressing GM-CSF in the lungs of severe COVID-19 patients.
Zhao Y, Kilian C, Turner JE, Bosurgi L, Roedl K, Bartsch P, Gnirck AC, Cortesi F, Schultheiß C, Hellmig M, Enk LUB, Hausmann F, Borchers A, Wong MN, Paust HJ, Siracusa F, Scheibel N, Herrmann M, Rosati E, Bacher P, Kylies D, Jarczak D, Lütgehetmann M, Pfefferle S, Steurer S, Zur-Wiesch JS, Puelles VG, Sperhake JP, Addo MM, Lohse AW, Binder M, Huber S, Huber TB, Kluge S, Bonn S, Panzer U, Gagliani N, Krebs CF. Zhao Y, et al. Sci Immunol. 2021 Feb 23;6(56):eabf6692. doi: 10.1126/sciimmunol.abf6692. Sci Immunol. 2021. PMID: 33622974 Free PMC article.
Pro-cachectic factors link experimental and human chronic kidney disease to skeletal muscle wasting programs.
Solagna F, Tezze C, Lindenmeyer MT, Lu S, Wu G, Liu S, Zhao Y, Mitchell R, Meyer C, Omairi S, Kilic T, Paolini A, Ritvos O, Pasternack A, Matsakas A, Kylies D, Wiesch JSZ, Turner JE, Wanner N, Nair V, Eichinger F, Menon R, Martin IV, Klinkhammer BM, Hoxha E, Cohen CD, Tharaux PL, Boor P, Ostendorf T, Kretzler M, Sandri M, Kretz O, Puelles VG, Patel K, Huber TB. Solagna F, et al. Among authors: zhao y. J Clin Invest. 2021 Jun 1;131(11):e135821. doi: 10.1172/JCI135821. J Clin Invest. 2021. PMID: 34060483 Free PMC article.
Th17 cell plasticity towards a T-bet-dependent Th1 phenotype is required for bacterial control in Staphylococcus aureus infection.
Bartsch P, Kilian C, Hellmig M, Paust HJ, Borchers A, Sivayoganathan A, Enk L, Zhao Y, Shaikh N, Büttner H, Wong MN, Puelles VG, Wiech T, Flavell R, Huber TB, Turner JE, Bonn S, Huber S, Gagliani N, Mittrücker HW, Rohde H, Panzer U, Krebs CF. Bartsch P, et al. Among authors: zhao y. PLoS Pathog. 2022 Apr 21;18(4):e1010430. doi: 10.1371/journal.ppat.1010430. eCollection 2022 Apr. PLoS Pathog. 2022. PMID: 35446923 Free PMC article.
Glucocorticoids target the CXCL9/CXCL10-CXCR3 axis and confer protection against immune-mediated kidney injury.
Riedel JH, Robben L, Paust HJ, Zhao Y, Asada N, Song N, Peters A, Kaffke A, Borchers A, Tiegs G, Seifert L, Tomas NM, Hoxha E, Wenzel UO, Huber TB, Wiech T, Turner JE, Krebs CF, Panzer U. Riedel JH, et al. Among authors: zhao y. JCI Insight. 2023 Jan 10;8(1):e160251. doi: 10.1172/jci.insight.160251. JCI Insight. 2023. PMID: 36355429 Free PMC article.
Multicytokine-producing CD4+ T cells characterize the livers of patients with NASH.
Woestemeier A, Scognamiglio P, Zhao Y, Wagner J, Muscate F, Casar C, Siracusa F, Cortesi F, Agalioti T, Müller S, Sagebiel A, Konczalla L, Wahib R, Karstens KF, Giannou AD, Duprée A, Wolter S, Wong MN, Mühlig AK, Bielecka AA, Bansal V, Zhang T, Mann O, Puelles VG, Huber TB, Lohse AW, Izbicki JR, Palm NW, Bonn S, Huber S, Gagliani N. Woestemeier A, et al. Among authors: zhao y. JCI Insight. 2023 Jan 10;8(1):e153831. doi: 10.1172/jci.insight.153831. JCI Insight. 2023. PMID: 36625344 Free PMC article.
Transcriptional and Clonal Characterization of Cytotoxic T Cells in Crescentic Glomerulonephritis.
Mueller A, Zhao Y, Cicek H, Paust HJ, Sivayoganathan A, Linke A, Wegscheid C, Wiech T, Huber TB, Meyer-Schwesinger C, Bonn S, Prinz I, Panzer U, Tiegs G, Krebs CF, Neumann K. Mueller A, et al. Among authors: zhao y. J Am Soc Nephrol. 2023 Jun 1;34(6):1003-1018. doi: 10.1681/ASN.0000000000000116. Epub 2023 Mar 13. J Am Soc Nephrol. 2023. PMID: 36913357 Free PMC article.
CD4+ T cells produce GM-CSF and drive immune-mediated glomerular disease by licensing monocyte-derived cells to produce MMP12.
Paust HJ, Song N, De Feo D, Asada N, Tuzlak S, Zhao Y, Riedel JH, Hellmig M, Sivayoganathan A, Peters A, Kaffke A, Borchers A, Wenzel UO, Steinmetz OM, Tiegs G, Meister E, Mack M, Kurts C, von Vietinghoff S, Lindenmeyer MT, Hoxha E, Stahl RAK, Huber TB, Bonn S, Meyer-Schwesinger C, Wiech T, Turner JE, Becher B, Krebs CF, Panzer U. Paust HJ, et al. Among authors: zhao y. Sci Transl Med. 2023 Mar 15;15(687):eadd6137. doi: 10.1126/scitranslmed.add6137. Epub 2023 Mar 15. Sci Transl Med. 2023. PMID: 36921033
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