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OxPhos defects cause hypermetabolism and reduce lifespan in cells and in patients with mitochondrial diseases.
Sturm G, Karan KR, Monzel AS, Santhanam B, Taivassalo T, Bris C, Ware SA, Cross M, Towheed A, Higgins-Chen A, McManus MJ, Cardenas A, Lin J, Epel ES, Rahman S, Vissing J, Grassi B, Levine M, Horvath S, Haller RG, Lenaers G, Wallace DC, St-Onge MP, Tavazoie S, Procaccio V, Kaufman BA, Seifert EL, Hirano M, Picard M. Sturm G, et al. Among authors: horvath s. Commun Biol. 2023 Jan 12;6(1):22. doi: 10.1038/s42003-022-04303-x. Commun Biol. 2023. PMID: 36635485 Free PMC article.
An epigenetic biomarker of aging for lifespan and healthspan.
Levine ME, Lu AT, Quach A, Chen BH, Assimes TL, Bandinelli S, Hou L, Baccarelli AA, Stewart JD, Li Y, Whitsel EA, Wilson JG, Reiner AP, Aviv A, Lohman K, Liu Y, Ferrucci L, Horvath S. Levine ME, et al. Among authors: horvath s. Aging (Albany NY). 2018 Apr 18;10(4):573-591. doi: 10.18632/aging.101414. Aging (Albany NY). 2018. PMID: 29676998 Free PMC article.
1,317 results