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Page 1
OxPhos defects cause hypermetabolism and reduce lifespan in cells and in patients with mitochondrial diseases.
Sturm G, Karan KR, Monzel AS, Santhanam B, Taivassalo T, Bris C, Ware SA, Cross M, Towheed A, Higgins-Chen A, McManus MJ, Cardenas A, Lin J, Epel ES, Rahman S, Vissing J, Grassi B, Levine M, Horvath S, Haller RG, Lenaers G, Wallace DC, St-Onge MP, Tavazoie S, Procaccio V, Kaufman BA, Seifert EL, Hirano M, Picard M. Sturm G, et al. Commun Biol. 2023 Jan 12;6(1):22. doi: 10.1038/s42003-022-04303-x. Commun Biol. 2023. PMID: 36635485 Free PMC article.
Acute psychological stress increases serum circulating cell-free mitochondrial DNA.
Trumpff C, Marsland AL, Basualto-Alarcón C, Martin JL, Carroll JE, Sturm G, Vincent AE, Mosharov EV, Gu Z, Kaufman BA, Picard M. Trumpff C, et al. Among authors: sturm g. Psychoneuroendocrinology. 2019 Aug;106:268-276. doi: 10.1016/j.psyneuen.2019.03.026. Epub 2019 Mar 28. Psychoneuroendocrinology. 2019. PMID: 31029929 Free PMC article.
Stress and circulating cell-free mitochondrial DNA: A systematic review of human studies, physiological considerations, and technical recommendations.
Trumpff C, Michelson J, Lagranha CJ, Taleon V, Karan KR, Sturm G, Lindqvist D, Fernström J, Moser D, Kaufman BA, Picard M. Trumpff C, et al. Among authors: sturm g. Mitochondrion. 2021 Jul;59:225-245. doi: 10.1016/j.mito.2021.04.002. Epub 2021 Apr 9. Mitochondrion. 2021. PMID: 33839318 Free PMC article. Review.
A computational solution for bolstering reliability of epigenetic clocks: Implications for clinical trials and longitudinal tracking.
Higgins-Chen AT, Thrush KL, Wang Y, Minteer CJ, Kuo PL, Wang M, Niimi P, Sturm G, Lin J, Moore AZ, Bandinelli S, Vinkers CH, Vermetten E, Rutten BPF, Geuze E, Okhuijsen-Pfeifer C, van der Horst MZ, Schreiter S, Gutwinski S, Luykx JJ, Picard M, Ferrucci L, Crimmins EM, Boks MP, Hägg S, Hu-Seliger TT, Levine ME. Higgins-Chen AT, et al. Among authors: sturm g. Nat Aging. 2022 Jul;2(7):644-661. doi: 10.1038/s43587-022-00248-2. Epub 2022 Jul 15. Nat Aging. 2022. PMID: 36277076 Free PMC article.
MitoQuicLy: a high-throughput method for quantifying cell-free DNA from human plasma, serum, and saliva.
Michelson J, Rausser S, Peng A, Yu T, Sturm G, Trumpff C, Kaufman BA, Rai AJ, Picard M. Michelson J, et al. Among authors: sturm g. bioRxiv [Preprint]. 2023 Jan 4:2023.01.04.522744. doi: 10.1101/2023.01.04.522744. bioRxiv. 2023. Update in: Mitochondrion. 2023 Jul;71:26-39. doi: 10.1016/j.mito.2023.05.001. PMID: 36711938 Free PMC article. Updated. Preprint.
Somatic nuclear mitochondrial DNA insertions are prevalent in the human brain and accumulate over time in fibroblasts.
Zhou W, Karan KR, Gu W, Klein HU, Sturm G, De Jager PL, Bennett DA, Hirano M, Picard M, Mills RE. Zhou W, et al. Among authors: sturm g. bioRxiv [Preprint]. 2023 Apr 21:2023.02.03.527065. doi: 10.1101/2023.02.03.527065. bioRxiv. 2023. Update in: PLoS Biol. 2024 Aug 22;22(8):e3002723. doi: 10.1371/journal.pbio.3002723. PMID: 36778249 Free PMC article. Updated. Preprint.
290 results