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Page 1
Branchpoint translocation by fork remodelers as a general mechanism of R-loop removal.
Hodson C, van Twest S, Dylewska M, O'Rourke JJ, Tan W, Murphy VJ, Walia M, Abbouche L, Nieminuszczy J, Dunn E, Bythell-Douglas R, Heierhorst J, Niedzwiedz W, Deans AJ. Hodson C, et al. Among authors: nieminuszczy j. Cell Rep. 2022 Dec 6;41(10):111749. doi: 10.1016/j.celrep.2022.111749. Cell Rep. 2022. PMID: 36476850 Free article.
SF3B1 hotspot mutations confer sensitivity to PARP inhibition by eliciting a defective replication stress response.
Bland P, Saville H, Wai PT, Curnow L, Muirhead G, Nieminuszczy J, Ravindran N, John MB, Hedayat S, Barker HE, Wright J, Yu L, Mavrommati I, Read A, Peck B, Allen M, Gazinska P, Pemberton HN, Gulati A, Nash S, Noor F, Guppy N, Roxanis I, Pratt G, Oldreive C, Stankovic T, Barlow S, Kalirai H, Coupland SE, Broderick R, Alsafadi S, Houy A, Stern MH, Pettit S, Choudhary JS, Haider S, Niedzwiedz W, Lord CJ, Natrajan R. Bland P, et al. Among authors: nieminuszczy j. Nat Genet. 2023 Aug;55(8):1311-1323. doi: 10.1038/s41588-023-01460-5. Epub 2023 Jul 31. Nat Genet. 2023. PMID: 37524790 Free PMC article.
Actin nucleators safeguard replication forks by limiting nascent strand degradation.
Nieminuszczy J, Martin PR, Broderick R, Krwawicz J, Kanellou A, Mocanu C, Bousgouni V, Smith C, Wen KK, Woodward BL, Bakal C, Shackley F, Aguilera A, Stewart GS, Vyas YM, Niedzwiedz W. Nieminuszczy J, et al. Nucleic Acids Res. 2023 Jul 7;51(12):6337-6354. doi: 10.1093/nar/gkad369. Nucleic Acids Res. 2023. PMID: 37224534 Free PMC article.
SMG8/SMG9 Heterodimer Loss Modulates SMG1 Kinase to Drive ATR Inhibitor Resistance.
Llorca-Cardenosa MJ, Aronson LI, Krastev DB, Nieminuszczy J, Alexander J, Song F, Dylewska M, Broderick R, Brough R, Zimmermann A, Zenke FT, Gurel B, Riisnaes R, Ferreira A, Roumeliotis T, Choudhary J, Pettitt SJ, de Bono J, Cervantes A, Haider S, Niedzwiedz W, Lord CJ, Chong IY. Llorca-Cardenosa MJ, et al. Among authors: nieminuszczy j. Cancer Res. 2022 Nov 2;82(21):3962-3973. doi: 10.1158/0008-5472.CAN-21-4339. Cancer Res. 2022. PMID: 36273494 Free PMC article.
Actin nucleators safeguard replication forks by limiting nascent strand degradation.
Nieminuszczy J, Martin PR, Broderick R, Krwawicz J, Kanellou A, Mocanu C, Bousgouni V, Smith C, Wen KK, Woodward BL, Bakal C, Shackley F, Aguilera A, Stewart GS, Vyas YM, Niedzwiedz W. Nieminuszczy J, et al. bioRxiv [Preprint]. 2023 Jan 12:2023.01.12.523639. doi: 10.1101/2023.01.12.523639. bioRxiv. 2023. Update in: Nucleic Acids Res. 2023 Jul 7;51(12):6337-6354. doi: 10.1093/nar/gkad369 PMID: 36711944 Free PMC article. Updated. Preprint.
Intrinsic neural stem cell properties define brain hypersensitivity to genotoxic stress.
Kalogeropoulou A, Mougkogianni M, Iliadou M, Nikolopoulou E, Flordelis S, Kanellou A, Arbi M, Nikou S, Nieminuszczy J, Niedzwiedz W, Kardamakis D, Bravou V, Lygerou Z, Taraviras S. Kalogeropoulou A, et al. Among authors: nieminuszczy j. Stem Cell Reports. 2022 Jun 14;17(6):1395-1410. doi: 10.1016/j.stemcr.2022.04.018. Epub 2022 May 26. Stem Cell Reports. 2022. PMID: 35623353 Free PMC article.
[SAMHD1 acts at stalled replication forks to prevent interferon induction].
Coquel F, Silva MJ, Técher H, Zadorozhny K, Sharma S, Nieminuszczy J, Mettling C, Dardillac E, Barthe A, Schmitz AL, Promonet A, Cribier A, Sarrazin A, Niedzwiedz W, Lopez B, Costanzo V, Krejci L, Chabes A, Benkirane M, Lin YL, Pasero P. Coquel F, et al. Among authors: nieminuszczy j. C R Biol. 2020 Jun 5;343(1):9-21. doi: 10.5802/crbiol.10. C R Biol. 2020. PMID: 32720483 Free article. Review. French.
37 results