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Tissue-Resident Memory T Cells in Pancreatic Ductal Adenocarcinoma Coexpress PD-1 and TIGIT and Functional Inhibition Is Reversible by Dual Antibody Blockade.
Pearce H, Croft W, Nicol SM, Margielewska-Davies S, Powell R, Cornall R, Davis SJ, Marcon F, Pugh MR, Fennell É, Powell-Brett S, Mahon BS, Brown RM, Middleton G, Roberts K, Moss P. Pearce H, et al. Among authors: middleton g. Cancer Immunol Res. 2023 Apr 3;11(4):435-449. doi: 10.1158/2326-6066.CIR-22-0121. Cancer Immunol Res. 2023. PMID: 36689623 Free PMC article.
Tetraspanin 6 is a regulator of carcinogenesis in colorectal cancer.
Andrijes R, Hejmadi RK, Pugh M, Rajesh S, Novitskaya V, Ibrahim M, Overduin M, Tselepis C, Middleton GW, Győrffy B, Beggs AD, Berditchevski F. Andrijes R, et al. Proc Natl Acad Sci U S A. 2021 Sep 28;118(39):e2011411118. doi: 10.1073/pnas.2011411118. Proc Natl Acad Sci U S A. 2021. PMID: 34521767 Free PMC article.
KRAS Mutation and Consensus Molecular Subtypes 2 and 3 Are Independently Associated with Reduced Immune Infiltration and Reactivity in Colorectal Cancer.
Lal N, White BS, Goussous G, Pickles O, Mason MJ, Beggs AD, Taniere P, Willcox BE, Guinney J, Middleton GW. Lal N, et al. Among authors: middleton gw. Clin Cancer Res. 2018 Jan 1;24(1):224-233. doi: 10.1158/1078-0432.CCR-17-1090. Epub 2017 Oct 23. Clin Cancer Res. 2018. PMID: 29061646 Free PMC article.
Tumor-Derived GM-CSF Promotes Granulocyte Immunosuppression in Mesothelioma Patients.
Khanna S, Graef S, Mussai F, Thomas A, Wali N, Yenidunya BG, Yuan C, Morrow B, Zhang J, Korangy F, Greten TF, Steinberg SM, Stetler-Stevenson M, Middleton G, De Santo C, Hassan R. Khanna S, et al. Among authors: middleton g. Clin Cancer Res. 2018 Jun 15;24(12):2859-2872. doi: 10.1158/1078-0432.CCR-17-3757. Epub 2018 Mar 30. Clin Cancer Res. 2018. PMID: 29602801 Free PMC article.
Development and Validation of a Combined Hypoxia and Immune Prognostic Classifier for Head and Neck Cancer.
Brooks JM, Menezes AN, Ibrahim M, Archer L, Lal N, Bagnall CJ, von Zeidler SV, Valentine HR, Spruce RJ, Batis N, Bryant JL, Hartley M, Kaul B, Ryan GB, Bao R, Khattri A, Lee SP, Ogbureke KUE, Middleton G, Tennant DA, Beggs AD, Deeks J, West CML, Cazier JB, Willcox BE, Seiwert TY, Mehanna H. Brooks JM, et al. Among authors: middleton g. Clin Cancer Res. 2019 Sep 1;25(17):5315-5328. doi: 10.1158/1078-0432.CCR-18-3314. Epub 2019 Jun 10. Clin Cancer Res. 2019. PMID: 31182433
350 results