Othman AA - Search Results

1

Effect of Renal Impairment on the Pharmacokinetics of Firsocostat, an Acetyl-Coenzyme A Carboxylase Inhibitor, and Cilofexor, a Selective Nonsteroidal Farnesoid X Receptor Agonist.

Weber E, Younis IR, Nelson C, Ding D, Qin A, Xiao D, Watkins TR, Othman AA. Weber E, et al. Among authors: othman aa. J Clin Pharmacol. 2023 May;63(5):560-568. doi: 10.1002/jcph.2206. Epub 2023 Feb 28. J Clin Pharmacol. 2023. PMID: 36700458 Clinical Trial.

2

Single- and multiple-dose pharmacokinetics, safety, and tolerability of the selective alpha7 neuronal nicotinic receptor agonist, ABT-107, in healthy human volunteers.

Othman AA, Lenz RA, Zhang J, Li J, Awni WM, Dutta S. Othman AA, et al. J Clin Pharmacol. 2011 Apr;51(4):512-26. doi: 10.1177/0091270010370460. Epub 2010 May 21. J Clin Pharmacol. 2011. PMID: 20495134 Clinical Trial.

3

Pharmacokinetics of the TRPV1 antagonist ABT-102 in healthy human volunteers: population analysis of data from 3 phase 1 trials.

Othman AA, Nothaft W, Awni WM, Dutta S. Othman AA, et al. J Clin Pharmacol. 2012 Jul;52(7):1028-41. doi: 10.1177/0091270011407497. Epub 2011 May 12. J Clin Pharmacol. 2012. PMID: 21566201

4

Effects of the TRPV1 antagonist ABT-102 on body temperature in healthy volunteers: pharmacokinetic/ pharmacodynamic analysis of three phase 1 trials.

Othman AA, Nothaft W, Awni WM, Dutta S. Othman AA, et al. Br J Clin Pharmacol. 2013 Apr;75(4):1029-40. doi: 10.1111/j.1365-2125.2012.04405.x. Br J Clin Pharmacol. 2013. PMID: 22966986 Free PMC article. Clinical Trial.

5

Safety, tolerability and pharmacokinetics of the histamine H3 receptor antagonist, ABT-288, in healthy young adults and elderly volunteers.

Othman AA, Haig G, Florian H, Locke C, Zhang J, Dutta S. Othman AA, et al. Br J Clin Pharmacol. 2013 May;75(5):1299-311. doi: 10.1111/j.1365-2125.2012.04472.x. Br J Clin Pharmacol. 2013. PMID: 23016924 Free PMC article. Clinical Trial.

6

Assessment of effect of CYP3A inhibition, CYP induction, OATP1B inhibition, and high-fat meal on pharmacokinetics of the JAK1 inhibitor upadacitinib.

Mohamed MF, Jungerwirth S, Asatryan A, Jiang P, Othman AA. Mohamed MF, et al. Among authors: othman aa. Br J Clin Pharmacol. 2017 Oct;83(10):2242-2248. doi: 10.1111/bcp.13329. Epub 2017 Jun 19. Br J Clin Pharmacol. 2017. PMID: 28503781 Free PMC article. Clinical Trial.

7

The JAK1 Inhibitor Upadacitinib Has No Effect on the Pharmacokinetics of Levonorgestrel and Ethinylestradiol: A Study in Healthy Female Subjects.

Mohamed MF, Trueman S, Feng T, Friedman A, Othman AA. Mohamed MF, et al. Among authors: othman aa. J Clin Pharmacol. 2019 Apr;59(4):510-516. doi: 10.1002/jcph.1350. Epub 2018 Nov 30. J Clin Pharmacol. 2019. PMID: 30500075 Free PMC article. Clinical Trial.

8

Characterization of the Effect of Renal Impairment on Upadacitinib Pharmacokinetics.

Mohamed MF, Trueman S, Feng T, Anderson J, Marbury TC, Othman AA. Mohamed MF, et al. Among authors: othman aa. J Clin Pharmacol. 2019 Jun;59(6):856-862. doi: 10.1002/jcph.1375. Epub 2019 Jan 11. J Clin Pharmacol. 2019. PMID: 30633369 Free PMC article.

9

Characterization of the Effect of Hepatic Impairment on Upadacitinib Pharmacokinetics.

Trueman S, Mohamed MF, Feng T, Lacerda AP, Marbury T, Othman AA. Trueman S, et al. Among authors: othman aa. J Clin Pharmacol. 2019 Sep;59(9):1188-1194. doi: 10.1002/jcph.1414. Epub 2019 Apr 11. J Clin Pharmacol. 2019. PMID: 30973649 Free PMC article.

10

Science and Evidence-Based Review and Approval of COVID-19 Vaccines: A Statement of Support for the US FDA.

Pai SM, Othman AA, Rusch L, Masters JC, Greene D, Rogge M, Gries JM, Clementi W, Kumar P, Younis I, Salem AH, Gaynes BI, Pastino G, Derendorf H; Public Policy Committee of the American College of Clinical Pharmacology. Pai SM, et al. Among authors: othman aa. J Clin Pharmacol. 2021 Mar;61(3):277-279. doi: 10.1002/jcph.1794. Epub 2021 Jan 27. J Clin Pharmacol. 2021. PMID: 33274473 Free PMC article. Review. No abstract available.

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