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Page 1
Treatment with the senolytics dasatinib/quercetin reduces SARS-CoV-2-related mortality in mice.
Pastor-Fernández A, Bertos AR, Sierra-Ramírez A, Del Moral-Salmoral J, Merino J, de Ávila AI, Olagüe C, Villares R, González-Aseguinolaza G, Rodríguez MÁ, Fresno M, Gironés N, Bustos M, Smerdou C, Fernandez-Marcos PJ, von Kobbe C. Pastor-Fernández A, et al. Among authors: sierra ramirez a. Aging Cell. 2023 Mar;22(3):e13771. doi: 10.1111/acel.13771. Epub 2023 Jan 26. Aging Cell. 2023. PMID: 36704839 Free PMC article.
Pharmacological and genetic increases in liver NADPH levels ameliorate NASH progression in female mice.
Rodriguez-Ramiro I, Pastor-Fernández A, López-Aceituno JL, Garcia-Dominguez E, Sierra-Ramirez A, Valverde AM, Martinez-Pastor B, Efeyan A, Gomez-Cabrera MC, Viña J, Fernandez-Marcos PJ. Rodriguez-Ramiro I, et al. Among authors: sierra ramirez a. Free Radic Biol Med. 2024 Jan;210:448-461. doi: 10.1016/j.freeradbiomed.2023.11.019. Epub 2023 Nov 29. Free Radic Biol Med. 2024. PMID: 38036067 Free article.
Peripheral modulation of antidepressant targets MAO-B and GABAAR by harmol induces mitohormesis and delays aging in preclinical models.
Costa-Machado LF, Garcia-Dominguez E, McIntyre RL, Lopez-Aceituno JL, Ballesteros-Gonzalez Á, Tapia-Gonzalez A, Fabregat-Safont D, Eisenberg T, Gomez J, Plaza A, Sierra-Ramirez A, Perez M, Villanueva-Bermejo D, Fornari T, Loza MI, Herradon G, Hofer SJ, Magnes C, Madeo F, Duerr JS, Pozo OJ, Galindo MI, Del Pino I, Houtkooper RH, Megias D, Viña J, Gomez-Cabrera MC, Fernandez-Marcos PJ. Costa-Machado LF, et al. Among authors: sierra ramirez a. Nat Commun. 2023 May 15;14(1):2779. doi: 10.1038/s41467-023-38410-y. Nat Commun. 2023. PMID: 37188705 Free PMC article.
17Beta-estradiol increases intracellular calcium concentration through a short-term and nongenomic mechanism in rat vascular endothelium in culture.
Rubio-Gayosso I, Sierra-Ramirez A, García-Vazquez A, Martinez-Martinez A, Muñoz-García O, Morato T, Ceballos-Reyes G. Rubio-Gayosso I, et al. Among authors: sierra ramirez a. J Cardiovasc Pharmacol. 2000 Aug;36(2):196-202. doi: 10.1097/00005344-200008000-00009. J Cardiovasc Pharmacol. 2000. PMID: 10942161