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In vitro to in vivo acetaminophen hepatotoxicity extrapolation using classical schemes, pharmacodynamic models and a multiscale spatial-temporal liver twin.
Dichamp J, Cellière G, Ghallab A, Hassan R, Boissier N, Hofmann U, Reinders J, Sezgin S, Zühlke S, Hengstler JG, Drasdo D. Dichamp J, et al. Among authors: celliere g. Front Bioeng Biotechnol. 2023 Feb 2;11:1049564. doi: 10.3389/fbioe.2023.1049564. eCollection 2023. Front Bioeng Biotechnol. 2023. PMID: 36815881 Free PMC article.
Establishing the suitability of model-integrated evidence to demonstrate bioequivalence for long-acting injectable and implantable drug products: Summary of workshop.
Gong Y, Zhang P, Yoon M, Zhu H, Kohojkar A, Hooker AC, Ducharme MP, Gobburu J, Cellière G, Gajjar P, Li BV, Velagapudi R, Tsang YC, Schwendeman A, Polli J, Fang L, Lionberger R, Zhao L. Gong Y, et al. Among authors: celliere g. CPT Pharmacometrics Syst Pharmacol. 2023 May;12(5):624-630. doi: 10.1002/psp4.12931. Epub 2023 Feb 9. CPT Pharmacometrics Syst Pharmacol. 2023. PMID: 36710372 Free PMC article. Review.
Model-guided identification of a therapeutic strategy to reduce hyperammonemia in liver diseases.
Ghallab A, Cellière G, Henkel SG, Driesch D, Hoehme S, Hofmann U, Zellmer S, Godoy P, Sachinidis A, Blaszkewicz M, Reif R, Marchan R, Kuepfer L, Häussinger D, Drasdo D, Gebhardt R, Hengstler JG. Ghallab A, et al. Among authors: celliere g. J Hepatol. 2016 Apr;64(4):860-71. doi: 10.1016/j.jhep.2015.11.018. Epub 2015 Nov 27. J Hepatol. 2016. PMID: 26639393 Free article.
Plasticity of TGF-β signaling.
Cellière G, Fengos G, Hervé M, Iber D. Cellière G, et al. BMC Syst Biol. 2011 Nov 3;5:184. doi: 10.1186/1752-0509-5-184. BMC Syst Biol. 2011. PMID: 22051045 Free PMC article.