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Evolutionary mismatch and the role of GxE interactions in human disease.
Lea AJ, Clark AG, Dahl AW, Devinsky O, Garcia AR, Golden CD, Kamau J, Kraft TS, Lim YAL, Martins D, Mogoi D, Pajukanta P, Perry G, Pontzer H, Trumble BC, Urlacher SS, Venkataraman VV, Wallace IJ, Gurven M, Lieberman D, Ayroles JF. Lea AJ, et al. ArXiv [Preprint]. 2023 Feb 13:arXiv:2301.05255v2. ArXiv. 2023. PMID: 36713247 Free PMC article. Preprint.
Genetic and environmental perturbations lead to regulatory decoherence.
Lea A, Subramaniam M, Ko A, Lehtimäki T, Raitoharju E, Kähönen M, Seppälä I, Mononen N, Raitakari OT, Ala-Korpela M, Pajukanta P, Zaitlen N, Ayroles JF. Lea A, et al. Elife. 2019 Mar 5;8:e40538. doi: 10.7554/eLife.40538. Elife. 2019. PMID: 30834892 Free PMC article.
Socioeconomic status effects on health vary between rural and urban Turkana.
Lea AJ, Waigwa C, Muhoya B, Lotukoi F, Peng J, Henry LP, Abhyankar V, Kamau J, Martins D, Gurven M, Ayroles JF. Lea AJ, et al. Evol Med Public Health. 2021 Nov 25;9(1):406-419. doi: 10.1093/emph/eoab039. eCollection 2021. Evol Med Public Health. 2021. PMID: 34987823 Free PMC article.
Natural selection of immune and metabolic genes associated with health in two lowland Bolivian populations.
Lea AJ, Garcia A, Arevalo J, Ayroles JF, Buetow K, Cole SW, Eid Rodriguez D, Gutierrez M, Highland HM, Hooper PL, Justice A, Kraft T, North KE, Stieglitz J, Kaplan H, Trumble BC, Gurven MD. Lea AJ, et al. Proc Natl Acad Sci U S A. 2023 Jan 3;120(1):e2207544120. doi: 10.1073/pnas.2207544120. Epub 2022 Dec 27. Proc Natl Acad Sci U S A. 2023. PMID: 36574663 Free PMC article.
Characterizing the landscape of gene expression variance in humans.
Wolf S, Melo D, Garske KM, Pallares LF, Lea AJ, Ayroles JF. Wolf S, et al. Among authors: lea aj. PLoS Genet. 2023 Jul 6;19(7):e1010833. doi: 10.1371/journal.pgen.1010833. eCollection 2023 Jul. PLoS Genet. 2023. PMID: 37410774 Free PMC article.
Apolipoprotein-ε4 is associated with higher fecundity in a natural fertility population.
Trumble BC, Charifson M, Kraft T, Garcia AR, Cummings DK, Hooper P, Lea AJ, Eid Rodriguez D, Koebele SV, Buetow K, Beheim B, Minocher R, Gutierrez M, Thomas GS, Gatz M, Stieglitz J, Finch CE, Kaplan H, Gurven M. Trumble BC, et al. Among authors: lea aj. Sci Adv. 2023 Aug 9;9(32):eade9797. doi: 10.1126/sciadv.ade9797. Epub 2023 Aug 9. Sci Adv. 2023. PMID: 37556539 Free PMC article.
81 results