Imaoka T - Search Results

1

Renal tubular transporter-mediated interactions between mirogabalin and cimetidine in rats.

Yamamura N, Imaoka T, Hoshi M, Yamada M, Itokawa KI. Yamamura N, et al. Among authors: imaoka t. Xenobiotica. 2023 Feb;53(2):114-122. doi: 10.1080/00498254.2023.2174916. Epub 2023 Feb 9. Xenobiotica. 2023. PMID: 36715563

2

Development of a novel gut microphysiological system that facilitates assessment of drug absorption kinetics in gut.

Imaoka T, Onuki-Nagasaki R, Kimura H, Tai K, Ishii M, Nozue A, Kaisaki I, Hoshi M, Watanabe K, Maeda K, Kamizono T, Yoshioka T, Fujimoto T, Satoh T, Nakamura H, Ando O, Kusuhara H, Ito Y. Imaoka T, et al. Sci Rep. 2024 Dec 2;14(1):29921. doi: 10.1038/s41598-024-80946-6. Sci Rep. 2024. PMID: 39622870 Free PMC article.

3

Integrated approach of in vivo and in vitro evaluation of the involvement of hepatic uptake organic anion transporters in the drug disposition in rats using rifampicin as an inhibitor.

Imaoka T, Mikkaichi T, Abe K, Hirouchi M, Okudaira N, Izumi T. Imaoka T, et al. Drug Metab Dispos. 2013 Jul;41(7):1442-9. doi: 10.1124/dmd.113.051052. Epub 2013 May 2. Drug Metab Dispos. 2013. PMID: 23640987

4

Edoxaban transport via P-glycoprotein is a key factor for the drug's disposition.

Mikkaichi T, Yoshigae Y, Masumoto H, Imaoka T, Rozehnal V, Fischer T, Okudaira N, Izumi T. Mikkaichi T, et al. Among authors: imaoka t. Drug Metab Dispos. 2014 Apr;42(4):520-8. doi: 10.1124/dmd.113.054866. Epub 2014 Jan 23. Drug Metab Dispos. 2014. PMID: 24459178

5

Curcumin as an In Vivo Selective Intestinal Breast Cancer Resistance Protein Inhibitor in Cynomolgus Monkeys.

Karibe T, Imaoka T, Abe K, Ando O. Karibe T, et al. Among authors: imaoka t. Drug Metab Dispos. 2018 May;46(5):667-679. doi: 10.1124/dmd.117.078931. Epub 2018 Jan 22. Drug Metab Dispos. 2018. PMID: 29358184

6

The renal-specific transporter mediates facilitative transport of organic anions at the brush border membrane of mouse renal tubules.

Imaoka T, Kusuhara H, Adachi-Akahane S, Hasegawa M, Morita N, Endou H, Sugiyama Y. Imaoka T, et al. J Am Soc Nephrol. 2004 Aug;15(8):2012-22. doi: 10.1097/01.ASN.0000135049.20420.E5. J Am Soc Nephrol. 2004. PMID: 15284287

7

Evaluation of the usefulness of breast cancer resistance protein (BCRP) knockout mice and BCRP inhibitor-treated monkeys to estimate the clinical impact of BCRP modulation on the pharmacokinetics of BCRP substrates.

Karibe T, Hagihara-Nakagomi R, Abe K, Imaoka T, Mikkaichi T, Yasuda S, Hirouchi M, Watanabe N, Okudaira N, Izumi T. Karibe T, et al. Among authors: imaoka t. Pharm Res. 2015 May;32(5):1634-47. doi: 10.1007/s11095-014-1563-4. Epub 2014 Nov 8. Pharm Res. 2015. PMID: 25380981

8

Liver-selective distribution in rats supports the importance of active uptake into the liver via organic anion transporting polypeptides (OATPs) in humans.

Mikkaichi T, Nakai D, Yoshigae Y, Imaoka T, Okudaira N, Izumi T. Mikkaichi T, et al. Among authors: imaoka t. Drug Metab Pharmacokinet. 2015 Oct;30(5):334-40. doi: 10.1016/j.dmpk.2015.06.003. Epub 2015 Jun 24. Drug Metab Pharmacokinet. 2015. PMID: 26403085

9

Recent Advances in the Gastrointestinal Complex in Vitro Model for ADME Studies.

Michiba K, Watanabe K, Imaoka T, Nakai D. Michiba K, et al. Among authors: imaoka t. Pharmaceutics. 2023 Dec 27;16(1):37. doi: 10.3390/pharmaceutics16010037. Pharmaceutics. 2023. PMID: 38258048 Free PMC article. Review.

10

Functional involvement of multidrug resistance-associated protein 4 (MRP4/ABCC4) in the renal elimination of the antiviral drugs adefovir and tenofovir.

Imaoka T, Kusuhara H, Adachi M, Schuetz JD, Takeuchi K, Sugiyama Y. Imaoka T, et al. Mol Pharmacol. 2007 Feb;71(2):619-27. doi: 10.1124/mol.106.028233. Epub 2006 Nov 16. Mol Pharmacol. 2007. PMID: 17110501

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