Yamada M - Search Results

1

Renal tubular transporter-mediated interactions between mirogabalin and cimetidine in rats.

Yamamura N, Imaoka T, Hoshi M, Yamada M, Itokawa KI. Yamamura N, et al. Among authors: yamada m. Xenobiotica. 2023 Feb;53(2):114-122. doi: 10.1080/00498254.2023.2174916. Epub 2023 Feb 9. Xenobiotica. 2023. PMID: 36715563

2

Pharmacokinetics, distribution, and disposition of esaxerenone, a novel, highly potent and selective non-steroidal mineralocorticoid receptor antagonist, in rats and monkeys.

Yamada M, Takei M, Suzuki E, Takakusa H, Kotsuma M, Washio T, Murayama N, Inoue SI, Izumi T. Yamada M, et al. Xenobiotica. 2017 Dec;47(12):1090-1103. doi: 10.1080/00498254.2016.1263766. Epub 2016 Dec 12. Xenobiotica. 2017. PMID: 27866463

3

Pharmacokinetics, Metabolism, and Excretion of [¹⁴C]Esaxerenone, a Novel Mineralocorticoid Receptor Blocker in Humans.

Yamada M, Mendell J, Takakusa H, Shimizu T, Ando O. Yamada M, et al. Drug Metab Dispos. 2019 Mar;47(3):340-349. doi: 10.1124/dmd.118.084897. Epub 2018 Dec 12. Drug Metab Dispos. 2019. PMID: 30541878 Clinical Trial.

4

Critical Impact of Drug-Drug Interactions via Intestinal CYP3A in the Risk Assessment of Weak Perpetrators Using Physiologically Based Pharmacokinetic Models.

Yamada M, Inoue SI, Sugiyama D, Nishiya Y, Ishizuka T, Watanabe A, Watanabe K, Yamashita S, Watanabe N. Yamada M, et al. Drug Metab Dispos. 2020 Apr;48(4):288-296. doi: 10.1124/dmd.119.089599. Epub 2020 Jan 29. Drug Metab Dispos. 2020. PMID: 31996361

5

Drug-Drug Interaction Risk Assessment of Esaxerenone as a Perpetrator by In Vitro Studies and Static and Physiologically Based Pharmacokinetic Models.

Yamada M, Ishizuka T, Inoue SI, Rozehnal V, Fischer T, Sugiyama D. Yamada M, et al. Drug Metab Dispos. 2020 Sep;48(9):769-777. doi: 10.1124/dmd.120.090928. Epub 2020 Jul 2. Drug Metab Dispos. 2020. PMID: 32616542

6

A novel compound, R-138329, increases plasma HDL cholesterol via inhibition of scavenger receptor BI-mediated selective lipid uptake.

Nishizawa T, Kitayama K, Wakabayashi K, Yamada M, Uchiyama M, Abe K, Ubukata N, Inaba T, Oda T, Amemiya Y. Nishizawa T, et al. Among authors: yamada m. Atherosclerosis. 2007 Oct;194(2):300-8. doi: 10.1016/j.atherosclerosis.2006.10.025. Epub 2006 Dec 12. Atherosclerosis. 2007. PMID: 17166497

7

Correction to: Physiologically based pharmacokinetic modelling to predict the clinical effect of CYP3A inhibitors/inducers on esaxerenone pharmacokinetics in healthy subjects and subjects with hepatic impairment.

Watanabe A, Ishizuka T, Yamada M, Igawa Y, Shimizu T, Ishizuka H. Watanabe A, et al. Among authors: yamada m. Eur J Clin Pharmacol. 2022 Jan;78(1):75. doi: 10.1007/s00228-021-03211-z. Eur J Clin Pharmacol. 2022. PMID: 34494163 Free PMC article. No abstract available.

8

Physiologically based pharmacokinetic modelling to predict the clinical effect of CYP3A inhibitors/inducers on esaxerenone pharmacokinetics in healthy subjects and subjects with hepatic impairment.

Watanabe A, Ishizuka T, Yamada M, Igawa Y, Shimizu T, Ishizuka H. Watanabe A, et al. Among authors: yamada m. Eur J Clin Pharmacol. 2022 Jan;78(1):65-73. doi: 10.1007/s00228-021-03194-x. Epub 2021 Aug 20. Eur J Clin Pharmacol. 2022. PMID: 34415382 Free PMC article. Clinical Trial.

9

[Pharmacological profile, clinical efficacy, and safety of esaxerenone (Minnebro^® tablets 1.25 mg, 2.5 mg, 5 mg)].

Yamakawa S, Homma T, Yamada M, Igawa Y, Yoshimura M. Yamakawa S, et al. Among authors: yamada m. Nihon Yakurigaku Zasshi. 2020;155(5):340-350. doi: 10.1254/fpj.20016. Nihon Yakurigaku Zasshi. 2020. PMID: 32879177 Japanese.

10

A Phase I, Single-Ascending-Dose Study in Healthy Subjects to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DS-2969b, a Novel GyrB Inhibitor.

Dennie J, Vandell AG, Inoue S, Gajee R, Pav J, Zhang G, Zamora C, Masuda N, Uchiyama M, Yamada M, Senaldi G. Dennie J, et al. Among authors: yamada m. J Clin Pharmacol. 2018 Dec;58(12):1557-1565. doi: 10.1002/jcph.1151. Epub 2018 May 10. J Clin Pharmacol. 2018. PMID: 29746725 Clinical Trial.

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