Cesura AM - Search Results

1

SDI-118, a novel procognitive SV2A modulator: First-in-human randomized controlled trial including PET/fMRI assessment of target engagement.

Botermans W, Koole M, Van Laere K, Savidge JR, Kemp JA, Sunaert S, Duffy MM, Ramael S, Cesura AM, D'Ostilio K, Gossen D, Madsen TM, Lodeweyckx T, de Hoon J. Botermans W, et al. Among authors: cesura am. Front Pharmacol. 2023 Jan 17;13:1066447. doi: 10.3389/fphar.2022.1066447. eCollection 2022. Front Pharmacol. 2023. PMID: 36733374 Free PMC article.

2

Sembragiline: A Novel, Selective Monoamine Oxidase Type B Inhibitor for the Treatment of Alzheimer's Disease.

Borroni E, Bohrmann B, Grueninger F, Prinssen E, Nave S, Loetscher H, Chinta SJ, Rajagopalan S, Rane A, Siddiqui A, Ellenbroek B, Messer J, Pähler A, Andersen JK, Wyler R, Cesura AM. Borroni E, et al. Among authors: cesura am. J Pharmacol Exp Ther. 2017 Sep;362(3):413-423. doi: 10.1124/jpet.117.241653. Epub 2017 Jun 22. J Pharmacol Exp Ther. 2017. PMID: 28642233

3

The mitochondrial effects of small organic ligands of BCL-2: sensitization of BCL-2-overexpressing cells to apoptosis by a pyrimidine-2,4,6-trione derivative.

Milanesi E, Costantini P, Gambalunga A, Colonna R, Petronilli V, Cabrelle A, Semenzato G, Cesura AM, Pinard E, Bernardi P. Milanesi E, et al. Among authors: cesura am. J Biol Chem. 2006 Apr 14;281(15):10066-72. doi: 10.1074/jbc.M513708200. Epub 2006 Feb 14. J Biol Chem. 2006. PMID: 16481323 Free article.

4

The voltage-dependent anion channel is the target for a new class of inhibitors of the mitochondrial permeability transition pore.

Cesura AM, Pinard E, Schubenel R, Goetschy V, Friedlein A, Langen H, Polcic P, Forte MA, Bernardi P, Kemp JA. Cesura AM, et al. J Biol Chem. 2003 Dec 12;278(50):49812-8. doi: 10.1074/jbc.M304748200. Epub 2003 Sep 2. J Biol Chem. 2003. PMID: 12952973 Free article.

5

Novel hexahydrospiro[piperidine-4,1'-pyrrolo[3,4-c]pyrroles]: highly selective small-molecule nociceptin/orphanin FQ receptor agonists.

Kolczewski S, Adam G, Cesura AM, Jenck F, Hennig M, Oberhauser T, Poli SM, Rössler F, Röver S, Wichmann J, Dautzenberg FM. Kolczewski S, et al. Among authors: cesura am. J Med Chem. 2003 Jan 16;46(2):255-64. doi: 10.1021/jm0209174. J Med Chem. 2003. PMID: 12519064

6

A preclinical re-evaluation of the safety profile of tolcapone.

Borroni E, Cesura AM, Gatti S, Gasser R. Borroni E, et al. Among authors: cesura am. Funct Neurol. 2001;16(4 Suppl):125-34. Funct Neurol. 2001. PMID: 11996507 Review. No abstract available.

7

High-affinity, non-peptide agonists for the ORL1 (orphanin FQ/nociceptin) receptor.

Röver S, Adam G, Cesura AM, Galley G, Jenck F, Monsma FJ Jr, Wichmann J, Dautzenberg FM. Röver S, et al. Among authors: cesura am. J Med Chem. 2000 Apr 6;43(7):1329-38. doi: 10.1021/jm991129q. J Med Chem. 2000. PMID: 10753470

8

Synthesis of (1S,3aS)-8-(2,3,3a,4,5, 6-hexahydro-1H-phenalen-1-yl)-1-phenyl-1,3,8-triaza-spiro[4. 5]decan-4-one, a potent and selective orphanin FQ (OFQ) receptor agonist with anxiolytic-like properties.

Wichmann J, Adam G, Röver S, Hennig M, Scalone M, Cesura AM, Dautzenberg FM, Jenck F. Wichmann J, et al. Among authors: cesura am. Eur J Med Chem. 2000 Sep;35(9):839-51. doi: 10.1016/s0223-5234(00)00171-9. Eur J Med Chem. 2000. PMID: 11006485

9

ORL1 receptor ligands: structure-activity relationships of 8-cycloalkyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-ones.

Röver S, Wichmann J, Jenck F, Adam G, Cesura AM. Röver S, et al. Among authors: cesura am. Bioorg Med Chem Lett. 2000 Apr 17;10(8):831-4. doi: 10.1016/s0960-894x(00)00111-6. Bioorg Med Chem Lett. 2000. PMID: 10782696

10

A synthetic agonist at the orphanin FQ/nociceptin receptor ORL1: anxiolytic profile in the rat.

Jenck F, Wichmann J, Dautzenberg FM, Moreau JL, Ouagazzal AM, Martin JR, Lundstrom K, Cesura AM, Poli SM, Roever S, Kolczewski S, Adam G, Kilpatrick G. Jenck F, et al. Among authors: cesura am. Proc Natl Acad Sci U S A. 2000 Apr 25;97(9):4938-43. doi: 10.1073/pnas.090514397. Proc Natl Acad Sci U S A. 2000. PMID: 10758169 Free PMC article.

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