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Phase II Study of Myeloablative 8/8- or 7/8-Matched Allotransplantation with Post-Transplant Cyclophosphamide, Tacrolimus, and Mycophenolate Mofetil: Marked Reduction in GVHD Risk Without Increased Relapse Risk Compared to Historical Cyclosporine/Methotrexate.
El Jurdi N, Hoover A, O'Leary D, Cao Q, Gupta A, Ebens C, Maakaron J, Betts BC, Rashidi A, Juckett M, Lund T, Bachanova V, MacMillan M, Miller J, Orchard P, Wagner J, Vercellotti G, Weisdorf D, Dusenbery K, Terezakis S, Holtan S. El Jurdi N, et al. medRxiv [Preprint]. 2023 Mar 29:2023.03.24.23287521. doi: 10.1101/2023.03.24.23287521. medRxiv. 2023. PMID: 37034603 Free PMC article. Preprint.
The BACH1 inhibitor ASP8731 inhibits inflammation and vaso-occlusion and induces fetal hemoglobin in sickle cell disease.
Belcher JD, Nataraja S, Abdulla F, Zhang P, Chen C, Nguyen J, Ruan C, Singh M, Demes S, Olson L, Stickens D, Stanwix J, Clarke E, Huang Y, Biddle M, Vercellotti GM. Belcher JD, et al. Among authors: vercellotti gm. Front Med (Lausanne). 2023 Apr 18;10:1101501. doi: 10.3389/fmed.2023.1101501. eCollection 2023. Front Med (Lausanne). 2023. PMID: 37144034 Free PMC article.
Phase II Study of Myeloablative 7-8/8-Matched Allotransplantation with Post-Transplantation Cyclophosphamide, Tacrolimus, and Mycophenolate Mofetil.
Jurdi NE, Hoover A, O'Leary D, Cao Q, Gupta A, Ebens C, Maakaron JE, Betts BC, Rashidi A, Juckett MB, Lund T, Bachanova V, MacMillan ML, Miller JS, Orchard PJ, Wagner JE, Vercellotti G, Weisdorf DJ, Dusenbery K, Terezakis S, Holtan SG. Jurdi NE, et al. Transplant Cell Ther. 2023 Sep;29(9):576.e1-576.e5. doi: 10.1016/j.jtct.2023.06.008. Epub 2023 Jun 11. Transplant Cell Ther. 2023. PMID: 37311510 Free PMC article. Clinical Trial.
Sickle red blood cell-derived extracellular vesicles activate endothelial cells and enhance sickle red cell adhesion mediated by von Willebrand factor.
An R, Man Y, Cheng K, Zhang T, Chen C, Wang F, Abdulla F, Kucukal E, Wulftange WJ, Goreke U, Bode A, Nayak LV, Vercellotti GM, Belcher JD, Little JA, Gurkan UA. An R, et al. Among authors: vercellotti gm. Br J Haematol. 2023 May;201(3):552-563. doi: 10.1111/bjh.18616. Epub 2023 Jan 5. Br J Haematol. 2023. PMID: 36604837 Free PMC article.
Factor XII contributes to thrombotic complications and vaso-occlusion in sickle cell disease.
Sparkenbaugh EM, Henderson MW, Miller-Awe M, Abrams C, Ilich A, Trebak F, Ramadas N, Vital S, Bohinc D, Bane KL, Chen C, Patel M, Wallisch M, Renné T, Gruber A, Cooley B, Gailani D, Kasztan M, Vercellotti GM, Belcher JD, Gavins FE, Stavrou EX, Key NS, Pawlinski R. Sparkenbaugh EM, et al. Among authors: vercellotti gm. Blood. 2023 Apr 13;141(15):1871-1883. doi: 10.1182/blood.2022017074. Blood. 2023. PMID: 36706361 Free PMC article.
Coagulation and platelet biology at the intersection of health and disease: illustrated capsules of the 11th Symposium on Hemostasis at the University of North Carolina.
Aleman M, Arepally GM, Baglin T, Buitrago L, Davizon-Castillo P, Dayal S, Flick MJ, Gerber G, Hisada Y, Kolev K, O'Loghlen A, Rezaie AR, Sparkenbaugh EM, Stavrou EX, Ünlü B, Vercellotti GM. Aleman M, et al. Among authors: vercellotti gm. Res Pract Thromb Haemost. 2024 Apr 3;8(3):102395. doi: 10.1016/j.rpth.2024.102395. eCollection 2024 Mar. Res Pract Thromb Haemost. 2024. PMID: 38699410 Free PMC article.
Endothelial cell provenance: an unclear role in transplant medicine.
Pace A, Steiner ME, Vercellotti GM, Somani A. Pace A, et al. Among authors: vercellotti gm. Front Transplant. 2023 Apr 28;2:1130941. doi: 10.3389/frtra.2023.1130941. eCollection 2023. Front Transplant. 2023. PMID: 38993867 Free PMC article. Review.
Allogeneic Hematopoietic Cell Transplant For Bone Marrow Failure or Myelodysplastic Syndrome in Dyskeratosis Congenita/Telomere Biology Disorders: Single-Center, Single-Arm, Open-Label Trial of Reduced-Intensity Conditioning Without Radiation.
Dimitrov M, Merkle S, Cao Q, Tryon RK, Vercellotti GM, Holtan SG, Kao RL, Srikanthan M, Terezakis SA, Tolar J, Ebens CL. Dimitrov M, et al. Among authors: vercellotti gm. Transplant Cell Ther. 2024 Oct;30(10):1005.e1-1005.e17. doi: 10.1016/j.jtct.2024.07.007. Epub 2024 Jul 11. Transplant Cell Ther. 2024. PMID: 39002862 Clinical Trial.
231 results