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481 results

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Page 1
Cytokine Hyperresponsiveness in Children With ETV6::RUNX1-positive Acute Lymphoblastic Leukemia After Challenge With Common Pathogens.
Rüchel N, Oldenburg M, Janssen S, Pandyra AA, Liu W, Vasileiou E, Hein D, Jepsen VH, Fischer U, Picard D, Kögler G, Hauer J, Auer F, Beer A, Adams O, MacKenzie C, Jaeger M, Netea MG, Borkhardt A, Gössling KL. Rüchel N, et al. Among authors: borkhardt a. Hemasphere. 2023 Jan 31;7(2):e835. doi: 10.1097/HS9.0000000000000835. eCollection 2023 Feb. Hemasphere. 2023. PMID: 36741356 Free PMC article. No abstract available.
Tacedinaline (CI-994), a class I HDAC inhibitor, targets intrinsic tumor growth and leptomeningeal dissemination in MYC-driven medulloblastoma while making them susceptible to anti-CD47-induced macrophage phagocytosis via NF-kB-TGM2 driven tumor inflammation.
Marquardt V, Theruvath J, Pauck D, Picard D, Qin N, Blümel L, Maue M, Bartl J, Ahmadov U, Langini M, Meyer FD, Cole A, Cruz-Cruz J, Graef CM, Wölfl M, Milde T, Witt O, Erdreich-Epstein A, Leprivier G, Kahlert U, Stefanski A, Stühler K, Keir ST, Bigner DD, Hauer J, Beez T, Knobbe-Thomsen CB, Fischer U, Felsberg J, Hansen FK, Vibhakar R, Venkatraman S, Cheshier SH, Reifenberger G, Borkhardt A, Kurz T, Remke M, Mitra S. Marquardt V, et al. Among authors: borkhardt a. J Immunother Cancer. 2023 Jan;11(1):e005871. doi: 10.1136/jitc-2022-005871. J Immunother Cancer. 2023. PMID: 36639156 Free PMC article.
Arenaviruses: Old viruses present new solutions for cancer therapy.
Stachura P, Stencel O, Lu Z, Borkhardt A, Pandyra AA. Stachura P, et al. Among authors: borkhardt a. Front Immunol. 2023 Mar 24;14:1110522. doi: 10.3389/fimmu.2023.1110522. eCollection 2023. Front Immunol. 2023. PMID: 37033933 Free PMC article. Review.
A clinical screening tool to detect genetic cancer predisposition in pediatric oncology shows high sensitivity but can miss a substantial percentage of affected children.
Friedrich UA, Bienias M, Zinke C, Prazenicova M, Lohse J, Jahn A, Menzel M, Langanke J, Walter C, Wagener R, Brozou T, Varghese J, Dugas M, Erlacher M, Schröck E, Suttorp M, Borkhardt A, Hauer J, Auer F. Friedrich UA, et al. Among authors: borkhardt a. Genet Med. 2023 Aug;25(8):100875. doi: 10.1016/j.gim.2023.100875. Epub 2023 May 3. Genet Med. 2023. PMID: 37149759 Free article.
Worms on stage.
Pandyra AA, Borkhardt A. Pandyra AA, et al. Among authors: borkhardt a. Haematologica. 2023 Dec 1;108(12):3201-3203. doi: 10.3324/haematol.2023.283709. Haematologica. 2023. PMID: 37439330 Free PMC article. No abstract available.
Unleashing T cell anti-tumor immunity: new potential for 5-Nonloxytryptamine as an agent mediating MHC-I upregulation in tumors.
Stachura P, Liu W, Xu HC, Wlodarczyk A, Stencel O, Pandey P, Vogt M, Bhatia S, Picard D, Remke M, Lang KS, Häussinger D, Homey B, Lang PA, Borkhardt A, Pandyra AA. Stachura P, et al. Among authors: borkhardt a. Mol Cancer. 2023 Aug 15;22(1):136. doi: 10.1186/s12943-023-01833-8. Mol Cancer. 2023. PMID: 37582744 Free PMC article.
Proteogenomic profiling uncovers differential therapeutic vulnerabilities between TCF3::PBX1 and TCF3::HLF translocated B-cell acute lymphoblastic leukemia.
Blumel L, Bernardi F, Picard D, Diaz JT, Jepsen VH, Hasselmann R, Schliehe-Diecks J, Bartl J, Qin N, Bornhauser B, Bhatia S, Marovka B, Marsaud V, Dingli F, Loew D, Stanulla M, Bourqin JP, Borkhardt A, Remke M, Ayrault O, Fischer U. Blumel L, et al. Among authors: borkhardt a. Haematologica. 2024 Jul 1;109(7):2290-2296. doi: 10.3324/haematol.2023.283928. Haematologica. 2024. PMID: 38426288 Free PMC article. No abstract available.
Deciphering the Therapeutic Potential of Novel Pentyloxyamide-Based Class I, IIb HDAC Inhibitors against Therapy-Resistant Leukemia.
Fischer F, Schliehe-Diecks J, Tu JW, Gangnus T, Ho YL, Hebeis M, Alves Avelar LA, Scharov K, Watrin T, Kemkes M, Stachura P, Daugs K, Biermann L, Kremeyer J, Horstick N, Span I, Pandyra AA, Borkhardt A, Gohlke H, Kassack MU, Burckhardt BB, Bhatia S, Kurz T. Fischer F, et al. Among authors: borkhardt a. J Med Chem. 2024 Nov 27. doi: 10.1021/acs.jmedchem.4c02024. Online ahead of print. J Med Chem. 2024. PMID: 39602240
Chemotherapy-related hyperbilirubinemia in pediatric acute lymphoblastic leukemia: a genome-wide association study from the AIEOP-BFM ALL study group.
Junk SV, Schaeffeler E, Zimmermann M, Möricke A, Beier R, Schütte P, Fedders B, Alten J, Hinze L, Klein N, Kulozik A, Muckenthaler MU, Koehler R, Borkhardt A, Vijayakrishnan J, Ellinghaus D, Forster M, Franke A, Wintering A, Kratz CP, Schrappe M, Schwab M, Houlston RS, Cario G, Stanulla M. Junk SV, et al. Among authors: borkhardt a. J Exp Clin Cancer Res. 2023 Jan 13;42(1):21. doi: 10.1186/s13046-022-02585-x. J Exp Clin Cancer Res. 2023. PMID: 36639636 Free PMC article.
481 results