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Combined KRASG12C and SOS1 inhibition enhances and extends the anti-tumor response in KRASG12C-driven cancers by addressing intrinsic and acquired resistance.
Thatikonda V, Lu H, Jurado S, Kostyrko K, Bristow CA, Bosch K, Feng N, Gao S, Gerlach D, Gmachl M, Lieb S, Jeschko A, Machado AA, Marszalek ED, Mahendra M, Jaeger PA, Sorokin A, Strauss S, Trapani F, Kopetz S, Vellano CP, Petronczki M, Kraut N, Heffernan TP, Marszalek JR, Pearson M, Waizenegger I, Hofmann MH. Thatikonda V, et al. Among authors: bosch k. bioRxiv [Preprint]. 2023 Jan 23:2023.01.23.525210. doi: 10.1101/2023.01.23.525210. bioRxiv. 2023. Update in: Nat Cancer. 2024 Sep;5(9):1352-1370. doi: 10.1038/s43018-024-00800-6 PMID: 36747713 Free PMC article. Updated. Preprint.
Co-targeting SOS1 enhances the antitumor effects of KRASG12C inhibitors by addressing intrinsic and acquired resistance.
Thatikonda V, Lyu H, Jurado S, Kostyrko K, Bristow CA, Albrecht C, Alpar D, Arnhof H, Bergner O, Bosch K, Feng N, Gao S, Gerlach D, Gmachl M, Hinkel M, Lieb S, Jeschko A, Machado AA, Madensky T, Marszalek ED, Mahendra M, Melo-Zainzinger G, Molkentine JM, Jaeger PA, Peng DH, Schenk RL, Sorokin A, Strauss S, Trapani F, Kopetz S, Vellano CP, Petronczki M, Kraut N, Heffernan TP, Marszalek JR, Pearson M, Waizenegger IC, Hofmann MH. Thatikonda V, et al. Among authors: bosch k. Nat Cancer. 2024 Sep;5(9):1352-1370. doi: 10.1038/s43018-024-00800-6. Epub 2024 Aug 5. Nat Cancer. 2024. PMID: 39103541 Free PMC article.
European Autism GEnomics Registry (EAGER): protocol for a multicentre cohort study and registry.
Bloomfield M, Lautarescu A, Heraty S, Douglas S, Violland P, Plas R, Ghosh A, Van den Bosch K, Eaton E, Absoud M, Battini R, Blázquez Hinojosa A, Bolshakova N, Bölte S, Bonanni P, Borg J, Calderoni S, Calvo Escalona R, Castelo-Branco M, Castro-Fornieles J, Caro P, Cliquet F, Danieli A, Delorme R, Elia M, Hempel M, Leblond CS, Madeira N, McAlonan G, Milone R, Molloy CJ, Mouga S, Montiel V, Pina Rodrigues A, Schaaf CP, Serrano M, Tammimies K, Tye C, Vigevano F, Oliveira G, Mazzone B, O'Neill C, Pender J, Romero V, Tillmann J, Oakley B, Murphy DGM, Gallagher L, Bourgeron T, Chatham C, Charman T. Bloomfield M, et al. Among authors: van den bosch k. BMJ Open. 2024 Jun 4;14(6):e080746. doi: 10.1136/bmjopen-2023-080746. BMJ Open. 2024. PMID: 38834317 Free PMC article.
30-day Morbidity and Mortality after Cholecystectomy for Benign Gallbladder Disease (AMBROSE): A Prospective, International Collaborative Cohort Study.
Wong GYM, Wadhawan H, Roth Cardoso V, Bravo Merodio L, Rajeev Y, Maldonado RD, Martinino A, Balasubaramaniam V, Ashraf A, Siddiqui A, Al-Shkirat AG, Mohammed Abu-Elfatth A, Gupta A, Alkaseek A, Ouyahia A, Said A, Pandey A, Kumar A, Maqbool B, Millán CA, Singh C, Pantoja Pachajoa DA, Adamovich DM, Petracchi E, Ashraf F, Clementi M, Mulita F, Marom GA, Abdulaal G, Verras GI, Calini G, Moretto G, Elfeki H, Liang H, Jalaawiy H, Elzayat I, Das JK, Aceves-Ayala JM, Ahmed KT, Degrate L, Aggarwal M, Omar MA, Rais M, Elhadi M, Sakran N, Bhojwani R, Agarwalla R, Kanaan S, Erdene S, Chooklin S, Khuroo S, Dawani S, Asghar ST, Fung TKJ, Omarov T, Grigorean VT, Boras Z, V Gkoutos G, Singhal R, Mahawar K; AMBROSE Collaborative. Wong GYM, et al. Ann Surg. 2024 Feb 13. doi: 10.1097/SLA.0000000000006236. Online ahead of print. Ann Surg. 2024. PMID: 38348652
Bridge-building between communities: Imagining the future of biomedical autism research.
Heraty S, Lautarescu A, Belton D, Boyle A, Cirrincione P, Doherty M, Douglas S, Plas JRD, Van Den Bosch K, Violland P, Tercon J, Ruigrok A, Murphy DGM, Bourgeron T, Chatham C, Loth E, Oakley B, McAlonan GM, Charman T, Puts N, Gallagher L, Jones EJH. Heraty S, et al. Among authors: van den bosch k. Cell. 2023 Aug 31;186(18):3747-3752. doi: 10.1016/j.cell.2023.08.004. Cell. 2023. PMID: 37657415 Free article.
176 results