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Compressed phenotypic screens for complex multicellular models and high-content assays.
Mead BE, Kummerlowe C, Liu N, Kattan WE, Cheng T, Cheah JH, Soule CK, Peters J, Lowder KE, Blainey PC, Hahn WC, Cleary B, Bryson B, Winter PS, Raghavan S, Shalek AK. Mead BE, et al. bioRxiv [Preprint]. 2023 Jan 23:2023.01.23.525189. doi: 10.1101/2023.01.23.525189. bioRxiv. 2023. PMID: 36747859 Free PMC article. Preprint.
Scalable, compressed phenotypic screening using pooled perturbations.
Liu N, Kattan WE, Mead BE, Kummerlowe C, Cheng T, Ingabire S, Cheah JH, Soule CK, Vrcic A, McIninch JK, Triana S, Guzman M, Dao TT, Peters JM, Lowder KE, Crawford L, Amini AP, Blainey PC, Hahn WC, Cleary B, Bryson B, Winter PS, Raghavan S, Shalek AK. Liu N, et al. Among authors: mead be. Nat Biotechnol. 2024 Oct 7. doi: 10.1038/s41587-024-02403-z. Online ahead of print. Nat Biotechnol. 2024. PMID: 39375446
Chronic metabolic stress drives developmental programs and loss of tissue functions in non-transformed liver that mirror tumor states and stratify survival.
Tzouanas CN, Sherman MS, Shay JES, Rubin AJ, Mead BE, Dao TT, Butzlaff T, Mana MD, Kolb KE, Walesky C, Pepe-Mooney BJ, Smith CJ, Prakadan SM, Ramseier ML, Tong EY, Joung J, Chi F, McMahon-Skates T, Winston CL, Jeong WJ, Aney KJ, Chen E, Nissim S, Zhang F, Deshpande V, Lauer GM, Yilmaz ÖH, Goessling W, Shalek AK. Tzouanas CN, et al. Among authors: mead be. bioRxiv [Preprint]. 2023 Dec 1:2023.11.30.569407. doi: 10.1101/2023.11.30.569407. bioRxiv. 2023. PMID: 38077056 Free PMC article. Preprint.
Cellular and transcriptional diversity over the course of human lactation.
Nyquist SK, Gao P, Haining TKJ, Retchin MR, Golan Y, Drake RS, Kolb K, Mead BE, Ahituv N, Martinez ME, Shalek AK, Berger B, Goods BA. Nyquist SK, et al. Among authors: mead be. Proc Natl Acad Sci U S A. 2022 Apr 12;119(15):e2121720119. doi: 10.1073/pnas.2121720119. Epub 2022 Apr 4. Proc Natl Acad Sci U S A. 2022. PMID: 35377806 Free PMC article.
Screening for modulators of the cellular composition of gut epithelia via organoid models of intestinal stem cell differentiation.
Mead BE, Hattori K, Levy L, Imada S, Goto N, Vukovic M, Sze D, Kummerlowe C, Matute JD, Duan J, Langer R, Blumberg RS, Ordovas-Montanes J, Yilmaz ÖH, Karp JM, Shalek AK. Mead BE, et al. Nat Biomed Eng. 2022 Apr;6(4):476-494. doi: 10.1038/s41551-022-00863-9. Epub 2022 Mar 21. Nat Biomed Eng. 2022. PMID: 35314801 Free PMC article.
Publisher Correction: Live cell tagging tracking and isolation for spatial transcriptomics using photoactivatable cell dyes.
Genshaft AS, Ziegler CGK, Tzouanas CN, Mead BE, Jaeger AM, Navia AW, King RP, Mana MD, Huang S, Mitsialis V, Snapper SB, Yilmaz ÖH, Jacks T, Van Humbeck JF, Shalek AK. Genshaft AS, et al. Among authors: mead be. Nat Commun. 2021 Sep 3;12(1):5361. doi: 10.1038/s41467-021-25672-7. Nat Commun. 2021. PMID: 34480027 Free PMC article. No abstract available.
Acute Experimental Barrier Injury Triggers Ulcerative Colitis-Specific Innate Hyperresponsiveness and Ulcerative Colitis-Type Microbiome Changes in Humans.
Seidelin JB, Bahl MI, Licht TR, Mead BE, Karp JM, Johansen JV, Riis LB, Galera MR, Woetmann A, Bjerrum JT. Seidelin JB, et al. Among authors: mead be. Cell Mol Gastroenterol Hepatol. 2021;12(4):1281-1296. doi: 10.1016/j.jcmgh.2021.06.002. Epub 2021 Jun 9. Cell Mol Gastroenterol Hepatol. 2021. PMID: 34118489 Free PMC article.
22 results