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Single-cell and spatial transcriptomics reveal aberrant lymphoid developmental programs driving granuloma formation.
Krausgruber T, Redl A, Barreca D, Doberer K, Romanovskaia D, Dobnikar L, Guarini M, Unterluggauer L, Kleissl L, Atzmüller D, Mayerhofer C, Kopf A, Saluzzo S, Lim CX, Rexie P, Weichhart T, Bock C, Stary G. Krausgruber T, et al. Among authors: rexie p. Immunity. 2023 Feb 14;56(2):289-306.e7. doi: 10.1016/j.immuni.2023.01.014. Epub 2023 Feb 6. Immunity. 2023. PMID: 36750099 Free PMC article.
SHP2 promotes sarcoidosis severity by inhibiting SKP2-targeted ubiquitination of TBET in CD8+ T cells.
Celada SI, Lim CX, Carisey AF, Ochsner SA, Arce Deza CF, Rexie P, Poli De Frias F, Cardenas-Castillo R, Polverino F, Hengstschläger M, Tsoyi K, McKenna NJ, Kheradmand F, Weichhart T, Rosas IO, Van Kaer L, Celada LJ. Celada SI, et al. Among authors: rexie p. Sci Transl Med. 2023 Sep 13;15(713):eade2581. doi: 10.1126/scitranslmed.ade2581. Epub 2023 Sep 13. Sci Transl Med. 2023. PMID: 37703351 Free PMC article.