Kulic L - Search Results

1

Mechanisms of amyloid-β34 generation indicate a pivotal role for BACE1 in amyloid homeostasis.

Ulku I, Liebsch F, Akerman SC, Schulz JF, Kulic L, Hock C, Pietrzik C, Di Spiezio A, Thinakaran G, Saftig P, Multhaup G. Ulku I, et al. Among authors: kulic l. Sci Rep. 2023 Feb 7;13(1):2216. doi: 10.1038/s41598-023-28846-z. Sci Rep. 2023. PMID: 36750595 Free PMC article.

2

Separation of presenilin function in amyloid beta-peptide generation and endoproteolysis of Notch.

Kulic L, Walter J, Multhaup G, Teplow DB, Baumeister R, Romig H, Capell A, Steiner H, Haass C. Kulic L, et al. Proc Natl Acad Sci U S A. 2000 May 23;97(11):5913-8. doi: 10.1073/pnas.100049897. Proc Natl Acad Sci U S A. 2000. PMID: 10811883 Free PMC article.

3

Active vaccination with ankyrin G reduces β-amyloid pathology in APP transgenic mice.

Santuccione AC, Merlini M, Shetty A, Tackenberg C, Bali J, Ferretti MT, McAfoose J, Kulic L, Bernreuther C, Welt T, Grimm J, Glatzel M, Rajendran L, Hock C, Nitsch RM. Santuccione AC, et al. Among authors: kulic l. Mol Psychiatry. 2013 Mar;18(3):358-68. doi: 10.1038/mp.2012.70. Epub 2012 Jun 12. Mol Psychiatry. 2013. PMID: 22688190

4

Early accumulation of intracellular fibrillar oligomers and late congophilic amyloid angiopathy in mice expressing the Osaka intra-Aβ APP mutation.

Kulic L, McAfoose J, Welt T, Tackenberg C, Späni C, Wirth F, Finder V, Konietzko U, Giese M, Eckert A, Noriaki K, Shimizu T, Murakami K, Irie K, Rasool S, Glabe C, Hock C, Nitsch RM. Kulic L, et al. Transl Psychiatry. 2012 Nov 13;2(11):e183. doi: 10.1038/tp.2012.109. Transl Psychiatry. 2012. PMID: 23149447 Free PMC article.

5

A human-derived antibody targets misfolded SOD1 and ameliorates motor symptoms in mouse models of amyotrophic lateral sclerosis.

Maier M, Welt T, Wirth F, Montrasio F, Preisig D, McAfoose J, Vieira FG, Kulic L, Späni C, Stehle T, Perrin S, Weber M, Hock C, Nitsch RM, Grimm J. Maier M, et al. Among authors: kulic l. Sci Transl Med. 2018 Dec 5;10(470):eaah3924. doi: 10.1126/scitranslmed.aah3924. Sci Transl Med. 2018. PMID: 30518612

6

Aβ34 is a BACE1-derived degradation intermediate associated with amyloid clearance and Alzheimer's disease progression.

Liebsch F, Kulic L, Teunissen C, Shobo A, Ulku I, Engelschalt V, Hancock MA, van der Flier WM, Kunach P, Rosa-Neto P, Scheltens P, Poirier J, Saftig P, Bateman RJ, Breitner J, Hock C, Multhaup G. Liebsch F, et al. Among authors: kulic l. Nat Commun. 2019 May 20;10(1):2240. doi: 10.1038/s41467-019-10152-w. Nat Commun. 2019. PMID: 31110178 Free PMC article.

7

The amyloid-β degradation intermediate Aβ34 is pericyte-associated and reduced in brain capillaries of patients with Alzheimer's disease.

Kirabali T, Rigotti S, Siccoli A, Liebsch F, Shobo A, Hock C, Nitsch RM, Multhaup G, Kulic L. Kirabali T, et al. Among authors: kulic l. Acta Neuropathol Commun. 2019 Dec 3;7(1):194. doi: 10.1186/s40478-019-0846-8. Acta Neuropathol Commun. 2019. PMID: 31796114 Free PMC article.

8

Familial Alzheimer's disease mutations at position 22 of the amyloid β-peptide sequence differentially affect synaptic loss, tau phosphorylation and neuronal cell death in an ex vivo system.

Tackenberg C, Kulic L, Nitsch RM. Tackenberg C, et al. Among authors: kulic l. PLoS One. 2020 Sep 23;15(9):e0239584. doi: 10.1371/journal.pone.0239584. eCollection 2020. PLoS One. 2020. PMID: 32966331 Free PMC article.

9

Early β-amyloid accumulation in the brain is associated with peripheral T cell alterations.

Gericke C, Kirabali T, Flury R, Mallone A, Rickenbach C, Kulic L, Tosevski V, Hock C, Nitsch RM, Treyer V, Ferretti MT, Gietl A. Gericke C, et al. Among authors: kulic l. Alzheimers Dement. 2023 Dec;19(12):5642-5662. doi: 10.1002/alz.13136. Epub 2023 Jun 14. Alzheimers Dement. 2023. PMID: 37314431

10

Acute Effects of Muscarinic M1 Receptor Modulation on AβPP Metabolism and Amyloid-β Levels in vivo: A Microdialysis Study.

Welt T, Kulic L, Hoey SE, McAfoose J, Späni C, Chadha AS, Fisher A, Nitsch RM. Welt T, et al. Among authors: kulic l. J Alzheimers Dis. 2015;46(4):971-82. doi: 10.3233/JAD-150152. J Alzheimers Dis. 2015. PMID: 25881909

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