Duan W - Search Results

1

Early detection of exon 1 huntingtin aggregation in zQ175 brains by molecular and histological approaches.

Smith EJ, Sathasivam K, Landles C, Osborne GF, Mason MA, Gomez-Paredes C, Taxy BA, Milton RE, Ast A, Schindler F, Zhang C, Duan W, Wanker EE, Bates GP. Smith EJ, et al. Among authors: duan w. Brain Commun. 2023 Jan 20;5(1):fcad010. doi: 10.1093/braincomms/fcad010. eCollection 2023. Brain Commun. 2023. PMID: 36756307 Free PMC article.

2

Abnormal Brain Development in Huntington' Disease Is Recapitulated in the zQ175 Knock-In Mouse Model.

Zhang C, Wu Q, Liu H, Cheng L, Hou Z, Mori S, Hua J, Ross CA, Zhang J, Nopoulos PC, Duan W. Zhang C, et al. Among authors: duan w. Cereb Cortex Commun. 2020;1(1):tgaa044. doi: 10.1093/texcom/tgaa044. Epub 2020 Aug 5. Cereb Cortex Commun. 2020. PMID: 32984817 Free PMC article.

3

Development of novel bioassays to detect soluble and aggregated Huntingtin proteins on three technology platforms.

Landles C, Milton RE, Jean A, McLarnon S, McAteer SJ, Taxy BA, Osborne GF, Zhang C, Duan W, Howland D, Bates GP. Landles C, et al. Among authors: duan w. Brain Commun. 2021 Jan 5;3(1):fcaa231. doi: 10.1093/braincomms/fcaa231. eCollection 2021. Brain Commun. 2021. PMID: 33604571 Free PMC article.

4

Huntingtin silencing delays onset and slows progression of Huntington's disease: a biomarker study.

Liu H, Zhang C, Xu J, Jin J, Cheng L, Miao X, Wu Q, Wei Z, Liu P, Lu H, van Zijl PCM, Ross CA, Hua J, Duan W. Liu H, et al. Among authors: duan w. Brain. 2021 Nov 29;144(10):3101-3113. doi: 10.1093/brain/awab190. Brain. 2021. PMID: 34043007 Free PMC article.

5

An RNA-targeting CRISPR-Cas13d system alleviates disease-related phenotypes in Huntington's disease models.

Morelli KH, Wu Q, Gosztyla ML, Liu H, Yao M, Zhang C, Chen J, Marina RJ, Lee K, Jones KL, Huang MY, Li A, Smith-Geater C, Thompson LM, Duan W, Yeo GW. Morelli KH, et al. Among authors: duan w. Nat Neurosci. 2023 Jan;26(1):27-38. doi: 10.1038/s41593-022-01207-1. Epub 2022 Dec 12. Nat Neurosci. 2023. PMID: 36510111 Free PMC article.

6

Transgenic mouse model expressing the caspase 6 fragment of mutant huntingtin.

Waldron-Roby E, Ratovitski T, Wang X, Jiang M, Watkin E, Arbez N, Graham RK, Hayden MR, Hou Z, Mori S, Swing D, Pletnikov M, Duan W, Tessarollo L, Ross CA. Waldron-Roby E, et al. Among authors: duan w. J Neurosci. 2012 Jan 4;32(1):183-93. doi: 10.1523/JNEUROSCI.1305-11.2012. J Neurosci. 2012. PMID: 22219281 Free PMC article.

7

Interrogation of brain miRNA and mRNA expression profiles reveals a molecular regulatory network that is perturbed by mutant huntingtin.

Jin J, Cheng Y, Zhang Y, Wood W, Peng Q, Hutchison E, Mattson MP, Becker KG, Duan W. Jin J, et al. Among authors: duan w. J Neurochem. 2012 Nov;123(4):477-90. doi: 10.1111/j.1471-4159.2012.07925.x. Epub 2012 Sep 28. J Neurochem. 2012. PMID: 22906125 Free PMC article.

8

Characterization of Behavioral, Neuropathological, Brain Metabolic and Key Molecular Changes in zQ175 Knock-In Mouse Model of Huntington's Disease.

Peng Q, Wu B, Jiang M, Jin J, Hou Z, Zheng J, Zhang J, Duan W. Peng Q, et al. Among authors: duan w. PLoS One. 2016 Feb 9;11(2):e0148839. doi: 10.1371/journal.pone.0148839. eCollection 2016. PLoS One. 2016. PMID: 26859386 Free PMC article.

9

Nemo-like kinase reduces mutant huntingtin levels and mitigates Huntington's disease.

Jiang M, Zhang X, Liu H, LeBron J, Alexandris A, Peng Q, Gu H, Yang F, Li Y, Wang R, Hou Z, Arbez N, Ren Q, Dong JL, Whela E, Wang R, Ratovitski T, Troncoso JC, Mori S, Ross CA, Lim J, Duan W. Jiang M, et al. Among authors: duan w. Hum Mol Genet. 2020 May 28;29(8):1340-1352. doi: 10.1093/hmg/ddaa061. Hum Mol Genet. 2020. PMID: 32242231 Free PMC article.

10

Interrogation of dynamic glucose-enhanced MRI and fluorescence-based imaging reveals a perturbed glymphatic network in Huntington's disease.

Liu H, Chen L, Zhang C, Liu C, Li Y, Cheng L, Wei Z, Zhang Z, Lu H, van Zijl PCM, Iliff JJ, Xu J, Duan W. Liu H, et al. Among authors: duan w. bioRxiv [Preprint]. 2023 Apr 3:2023.04.03.535397. doi: 10.1101/2023.04.03.535397. bioRxiv. 2023. PMID: 37066166 Free PMC article. Preprint.

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