Abdelwahed KS - Search Results

1

Towards Developing Novel Prostate Cancer Recurrence Suppressors: Acute Toxicity of Pseurotin A, an Orally Active PCSK9 Axis-Targeting Small-Molecule in Swiss Albino Mice.

McGehee OC, Ebrahim HY, Rad AH, Abdelwahed KS, Mudhish EA, King JA, Helal IE, Meyer SA, El Sayed KA. McGehee OC, et al. Among authors: abdelwahed ks. Molecules. 2023 Feb 2;28(3):1460. doi: 10.3390/molecules28031460. Molecules. 2023. PMID: 36771126 Free PMC article.

2

Safety Evaluations of Single Dose of the Olive Secoiridoid S-(-)-Oleocanthal in Swiss Albino Mice.

Siddique AB, King JA, Meyer SA, Abdelwahed K, Busnena B, El Sayed K. Siddique AB, et al. Nutrients. 2020 Jan 25;12(2):314. doi: 10.3390/nu12020314. Nutrients. 2020. PMID: 31991771 Free PMC article.

3

Pseurotin A as a novel suppressor of hormone dependent breast cancer progression and recurrence by inhibiting PCSK9 secretion and interaction with LDL receptor.

Abdelwahed KS, Siddique AB, Mohyeldin MM, Qusa MH, Goda AA, Singh SS, Ayoub NM, King JA, Jois SD, El Sayed KA. Abdelwahed KS, et al. Pharmacol Res. 2020 Aug;158:104847. doi: 10.1016/j.phrs.2020.104847. Epub 2020 May 11. Pharmacol Res. 2020. PMID: 32438039 Free PMC article.

4

Olive Oil Lignan (+)-Acetoxypinoresinol Peripheral Motor and Neuronal Protection against the Tremorgenic Mycotoxin Penitrem A Toxicity via STAT1 Pathway.

Qusa MH, Abdelwahed KS, Meyer SA, El Sayed KA. Qusa MH, et al. Among authors: abdelwahed ks. ACS Chem Neurosci. 2020 Nov 4;11(21):3575-3589. doi: 10.1021/acschemneuro.0c00458. Epub 2020 Oct 13. ACS Chem Neurosci. 2020. PMID: 32991800

5

HER2 Kinase-Targeted Breast Cancer Therapy: Design, Synthesis, and In Vitro and In Vivo Evaluation of Novel Lapatinib Congeners as Selective and Potent HER2 Inhibitors with Favorable Metabolic Stability.

Elwaie TA, Abbas SE, Aly EI, George RF, Ali H, Kraiouchkine N, Abdelwahed KS, Fandy TE, El Sayed KA, Abd Elmageed ZY, Ali HI. Elwaie TA, et al. Among authors: abdelwahed ks. J Med Chem. 2020 Dec 24;63(24):15906-15945. doi: 10.1021/acs.jmedchem.0c01647. Epub 2020 Dec 14. J Med Chem. 2020. PMID: 33314925

6

(-)-Oleocanthal Nutraceuticals for Alzheimer's Disease Amyloid Pathology: Novel Oral Formulations, Therapeutic, and Molecular Insights in 5xFAD Transgenic Mice Model.

Tajmim A, Cuevas-Ocampo AK, Siddique AB, Qusa MH, King JA, Abdelwahed KS, Sonju JJ, El Sayed KA. Tajmim A, et al. Among authors: abdelwahed ks. Nutrients. 2021 May 18;13(5):1702. doi: 10.3390/nu13051702. Nutrients. 2021. PMID: 34069842 Free PMC article.

7

Comparative Gene Signature of (-)-Oleocanthal Formulation Treatments in Heterogeneous Triple Negative Breast Tumor Models: Oncological Therapeutic Target Insights.

Qusa MH, Abdelwahed KS, Siddique AB, El Sayed KA. Qusa MH, et al. Among authors: abdelwahed ks. Nutrients. 2021 May 18;13(5):1706. doi: 10.3390/nu13051706. Nutrients. 2021. PMID: 34069906 Free PMC article.

8

PCSK9 Axis-Targeting Pseurotin A as a Novel Prostate Cancer Recurrence Suppressor Lead.

Abdelwahed KS, Siddique AB, Qusa MH, King JA, Souid S, Abd Elmageed ZY, El Sayed KA. Abdelwahed KS, et al. ACS Pharmacol Transl Sci. 2021 Oct 5;4(6):1771-1781. doi: 10.1021/acsptsci.1c00145. eCollection 2021 Dec 10. ACS Pharmacol Transl Sci. 2021. PMID: 34927009 Free PMC article.

9

The Tobacco β-Cembrenediol: A Prostate Cancer Recurrence Suppressor Lead and Prospective Scaffold via Modulation of Indoleamine 2,3-Dioxygenase and Tryptophan Dioxygenase.

Mudhish EA, Siddique AB, Ebrahim HY, Abdelwahed KS, King JA, El Sayed KA. Mudhish EA, et al. Among authors: abdelwahed ks. Nutrients. 2022 Apr 4;14(7):1505. doi: 10.3390/nu14071505. Nutrients. 2022. PMID: 35406118 Free PMC article.

10

Oleocanthal Attenuates Metastatic Castration-Resistant Prostate Cancer Progression and Recurrence by Targeting SMYD2.

Siddique AB, Ebrahim HY, Tajmim A, King JA, Abdelwahed KS, Abd Elmageed ZY, El Sayed KA. Siddique AB, et al. Among authors: abdelwahed ks. Cancers (Basel). 2022 Jul 21;14(14):3542. doi: 10.3390/cancers14143542. Cancers (Basel). 2022. PMID: 35884603 Free PMC article.

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