Hughson AG - Search Results

1

Sporadic Creutzfeldt-Jakob disease infected human cerebral organoids retain the original human brain subtype features following transmission to humanized transgenic mice.

Groveman BR, Race B, Foliaki ST, Williams K, Hughson AG, Baune C, Zanusso G, Haigh CL. Groveman BR, et al. Among authors: hughson ag. Acta Neuropathol Commun. 2023 Feb 14;11(1):28. doi: 10.1186/s40478-023-01512-1. Acta Neuropathol Commun. 2023. PMID: 36788566 Free PMC article.

2

Analysis of protein structure in intact cells: crosslinking in vivo between introduced cysteines in the transmembrane domain of a bacterial chemoreceptor.

Hughson AG, Lee GF, Hazelbauer GL. Hughson AG, et al. Protein Sci. 1997 Feb;6(2):315-22. doi: 10.1002/pro.5560060206. Protein Sci. 1997. PMID: 9041632 Free PMC article.

3

Detecting the conformational change of transmembrane signaling in a bacterial chemoreceptor by measuring effects on disulfide cross-linking in vivo.

Hughson AG, Hazelbauer GL. Hughson AG, et al. Proc Natl Acad Sci U S A. 1996 Oct 15;93(21):11546-51. doi: 10.1073/pnas.93.21.11546. Proc Natl Acad Sci U S A. 1996. PMID: 8876172 Free PMC article.

4

Human variant Creutzfeldt-Jakob disease and sheep scrapie PrP(res) detection using seeded conversion of recombinant prion protein.

Orrú CD, Wilham JM, Hughson AG, Raymond LD, McNally KL, Bossers A, Ligios C, Caughey B. Orrú CD, et al. Among authors: hughson ag. Protein Eng Des Sel. 2009 Aug;22(8):515-21. doi: 10.1093/protein/gzp031. Epub 2009 Jul 1. Protein Eng Des Sel. 2009. PMID: 19570812 Free PMC article.

5

Time course of prion seeding activity in cerebrospinal fluid of scrapie-infected hamsters after intratongue and intracerebral inoculations.

Orrù CD, Hughson AG, Race B, Raymond GJ, Caughey B. Orrù CD, et al. Among authors: hughson ag. J Clin Microbiol. 2012 Apr;50(4):1464-6. doi: 10.1128/JCM.06099-11. Epub 2012 Jan 11. J Clin Microbiol. 2012. PMID: 22238438 Free PMC article.

6

Isolation of novel synthetic prion strains by amplification in transgenic mice coexpressing wild-type and anchorless prion proteins.

Raymond GJ, Race B, Hollister JR, Offerdahl DK, Moore RA, Kodali R, Raymond LD, Hughson AG, Rosenke R, Long D, Dorward DW, Baron GS. Raymond GJ, et al. Among authors: hughson ag. J Virol. 2012 Nov;86(21):11763-78. doi: 10.1128/JVI.01353-12. Epub 2012 Aug 22. J Virol. 2012. PMID: 22915801 Free PMC article.

7

Prion seeding activities of mouse scrapie strains with divergent PrPSc protease sensitivities and amyloid plaque content using RT-QuIC and eQuIC.

Vascellari S, Orrù CD, Hughson AG, King D, Barron R, Wilham JM, Baron GS, Race B, Pani A, Caughey B. Vascellari S, et al. Among authors: hughson ag. PLoS One. 2012;7(11):e48969. doi: 10.1371/journal.pone.0048969. Epub 2012 Nov 5. PLoS One. 2012. PMID: 23139828 Free PMC article.

8

A test for Creutzfeldt-Jakob disease using nasal brushings.

Orrú CD, Bongianni M, Tonoli G, Ferrari S, Hughson AG, Groveman BR, Fiorini M, Pocchiari M, Monaco S, Caughey B, Zanusso G. Orrú CD, et al. Among authors: hughson ag. N Engl J Med. 2014 Aug 7;371(6):519-29. doi: 10.1056/NEJMoa1315200. N Engl J Med. 2014. PMID: 25099576 Free PMC article.

9

Rapid and sensitive RT-QuIC detection of human Creutzfeldt-Jakob disease using cerebrospinal fluid.

Orrú CD, Groveman BR, Hughson AG, Zanusso G, Coulthart MB, Caughey B. Orrú CD, et al. Among authors: hughson ag. mBio. 2015 Jan 20;6(1):e02451-14. doi: 10.1128/mBio.02451-14. mBio. 2015. PMID: 25604790 Free PMC article.

10

Detection and discrimination of classical and atypical L-type bovine spongiform encephalopathy by real-time quaking-induced conversion.

Orrú CD, Favole A, Corona C, Mazza M, Manca M, Groveman BR, Hughson AG, Acutis PL, Caramelli M, Zanusso G, Casalone C, Caughey B. Orrú CD, et al. Among authors: hughson ag. J Clin Microbiol. 2015 Apr;53(4):1115-20. doi: 10.1128/JCM.02906-14. Epub 2015 Jan 21. J Clin Microbiol. 2015. PMID: 25609728 Free PMC article.

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