Molenaar MR - Search Results

1

Lipidomic profiling of rat hepatic stellate cells during activation reveals a two-stage process accompanied by increased levels of lysosomal lipids.

Molenaar MR, Haaker MW, Vaandrager AB, Houweling M, Helms JB. Molenaar MR, et al. J Biol Chem. 2023 Apr;299(4):103042. doi: 10.1016/j.jbc.2023.103042. Epub 2023 Feb 18. J Biol Chem. 2023. PMID: 36803964 Free PMC article.

2

Lysosome-mediated degradation of a distinct pool of lipid droplets during hepatic stellate cell activation.

Tuohetahuntila M, Molenaar MR, Spee B, Brouwers JF, Wubbolts R, Houweling M, Yan C, Du H, VanderVen BC, Vaandrager AB, Helms JB. Tuohetahuntila M, et al. Among authors: molenaar mr. J Biol Chem. 2017 Jul 28;292(30):12436-12448. doi: 10.1074/jbc.M117.778472. Epub 2017 Jun 14. J Biol Chem. 2017. PMID: 28615446 Free PMC article.

3

Role of long-chain acyl-CoA synthetase 4 in formation of polyunsaturated lipid species in hepatic stellate cells.

Tuohetahuntila M, Spee B, Kruitwagen HS, Wubbolts R, Brouwers JF, van de Lest CH, Molenaar MR, Houweling M, Helms JB, Vaandrager AB. Tuohetahuntila M, et al. Among authors: molenaar mr. Biochim Biophys Acta. 2015 Feb;1851(2):220-30. doi: 10.1016/j.bbalip.2014.12.003. Epub 2014 Dec 9. Biochim Biophys Acta. 2015. PMID: 25500141

4

ATGL and DGAT1 are involved in the turnover of newly synthesized triacylglycerols in hepatic stellate cells.

Tuohetahuntila M, Molenaar MR, Spee B, Brouwers JF, Houweling M, Vaandrager AB, Helms JB. Tuohetahuntila M, et al. Among authors: molenaar mr. J Lipid Res. 2016 Jul;57(7):1162-74. doi: 10.1194/jlr.M066415. Epub 2016 May 14. J Lipid Res. 2016. PMID: 27179362 Free PMC article.

5

Hepatic stellate cells retain the capacity to synthesize retinyl esters and to store neutral lipids in small lipid droplets in the absence of LRAT.

Ajat M, Molenaar M, Brouwers JFHM, Vaandrager AB, Houweling M, Helms JB. Ajat M, et al. Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Feb;1862(2):176-187. doi: 10.1016/j.bbalip.2016.10.013. Epub 2016 Nov 1. Biochim Biophys Acta Mol Cell Biol Lipids. 2017. PMID: 27815220 Free article.

6

Some Lipid Droplets Are More Equal Than Others: Different Metabolic Lipid Droplet Pools in Hepatic Stellate Cells.

Molenaar MR, Vaandrager AB, Helms JB. Molenaar MR, et al. Lipid Insights. 2017 Dec 15;10:1178635317747281. doi: 10.1177/1178635317747281. eCollection 2017. Lipid Insights. 2017. PMID: 29276391 Free PMC article.

7

LION/web: a web-based ontology enrichment tool for lipidomic data analysis.

Molenaar MR, Jeucken A, Wassenaar TA, van de Lest CHA, Brouwers JF, Helms JB. Molenaar MR, et al. Gigascience. 2019 Jun 1;8(6):giz061. doi: 10.1093/gigascience/giz061. Gigascience. 2019. PMID: 31141612 Free PMC article.

8

Playing Jekyll and Hyde-The Dual Role of Lipids in Fatty Liver Disease.

Molenaar MR, Penning LC, Helms JB. Molenaar MR, et al. Cells. 2020 Oct 6;9(10):2244. doi: 10.3390/cells9102244. Cells. 2020. PMID: 33036257 Free PMC article. Review.

9

Identification of potential drugs for treatment of hepatic lipidosis in cats using an in vitro feline liver organoid system.

Haaker MW, Kruitwagen HS, Vaandrager AB, Houweling M, Penning LC, Molenaar MR, van Wolferen ME, Oosterhoff LA, Spee B, Helms JB. Haaker MW, et al. Among authors: molenaar mr. J Vet Intern Med. 2020 Jan;34(1):132-138. doi: 10.1111/jvim.15670. Epub 2019 Dec 12. J Vet Intern Med. 2020. PMID: 31830357 Free PMC article.

10

Retinyl esters form lipid droplets independently of triacylglycerol and seipin.

Molenaar MR, Yadav KK, Toulmay A, Wassenaar TA, Mari MC, Caillon L, Chorlay A, Lukmantara IE, Haaker MW, Wubbolts RW, Houweling M, Vaandrager AB, Prieur X, Reggiori F, Choudhary V, Yang H, Schneiter R, Thiam AR, Prinz WA, Helms JB. Molenaar MR, et al. J Cell Biol. 2021 Oct 4;220(10):e202011071. doi: 10.1083/jcb.202011071. Epub 2021 Jul 29. J Cell Biol. 2021. PMID: 34323918 Free PMC article.

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