De Brabander JK - Search Results

1

Evaluation of the efficacy of the hypocretin/orexin receptor agonists TAK-925 and ARN-776 in narcoleptic orexin/tTA; TetO-DTA mice.

Sun Y, Ranjan A, Tisdale R, Ma SC, Park S, Haire M, Heu J, Morairty SR, Wang X, Rosenbaum DM, Williams NS, De Brabander JK, Kilduff TS. Sun Y, et al. Among authors: de brabander jk. J Sleep Res. 2023 Aug;32(4):e13839. doi: 10.1111/jsr.13839. Epub 2023 Feb 20. J Sleep Res. 2023. PMID: 36808670 Free PMC article.

2

Inhibition by cellular vacuolar ATPase impairs human papillomavirus uncoating and infection.

Müller KH, Spoden GA, Scheffer KD, Brunnhöfer R, De Brabander JK, Maier ME, Florin L, Muller CP. Müller KH, et al. Among authors: de brabander jk. Antimicrob Agents Chemother. 2014 May;58(5):2905-11. doi: 10.1128/AAC.02284-13. Epub 2014 Mar 10. Antimicrob Agents Chemother. 2014. PMID: 24614368 Free PMC article.

3

The design, computer modeling, solution structure, and biological evaluation of synthetic analogs of bryostatin 1.

Wender PA, DeBrabander J, Harran PG, Jimenez JM, Koehler MF, Lippa B, Park CM, Siedenbiedel C, Pettit GR. Wender PA, et al. Proc Natl Acad Sci U S A. 1998 Jun 9;95(12):6624-9. doi: 10.1073/pnas.95.12.6624. Proc Natl Acad Sci U S A. 1998. PMID: 9618462 Free PMC article.

4

The proton translocation domain of cellular vacuolar ATPase provides a target for the treatment of influenza A virus infections.

Müller KH, Kainov DE, El Bakkouri K, Saelens X, De Brabander JK, Kittel C, Samm E, Muller CP. Müller KH, et al. Among authors: de brabander jk. Br J Pharmacol. 2011 Sep;164(2):344-57. doi: 10.1111/j.1476-5381.2011.01346.x. Br J Pharmacol. 2011. PMID: 21418188 Free PMC article.

5

Inhibition of influenza A virus infection in vitro by saliphenylhalamide-loaded porous silicon nanoparticles.

Bimbo LM, Denisova OV, Mäkilä E, Kaasalainen M, De Brabander JK, Hirvonen J, Salonen J, Kakkola L, Kainov D, Santos HA. Bimbo LM, et al. Among authors: de brabander jk. ACS Nano. 2013 Aug 27;7(8):6884-93. doi: 10.1021/nn402062f. Epub 2013 Aug 1. ACS Nano. 2013. PMID: 23889734

6

A Medicinal Chemistry-Driven Approach Identified the Sterol Isomerase EBP as the Molecular Target of TASIN Colorectal Cancer Toxins.

Theodoropoulos PC, Wang W, Budhipramono A, Thompson BM, Madhusudhan N, Mitsche MA, McDonald JG, De Brabander JK, Nijhawan D. Theodoropoulos PC, et al. Among authors: de brabander jk. J Am Chem Soc. 2020 Apr 1;142(13):6128-6138. doi: 10.1021/jacs.9b13407. Epub 2020 Mar 19. J Am Chem Soc. 2020. PMID: 32163279 Free PMC article.

7

Salicylihalamide A inhibits the V0 sector of the V-ATPase through a mechanism distinct from bafilomycin A1.

Xie XS, Padron D, Liao X, Wang J, Roth MG, De Brabander JK. Xie XS, et al. Among authors: de brabander jk. J Biol Chem. 2004 May 7;279(19):19755-63. doi: 10.1074/jbc.M313796200. Epub 2004 Mar 3. J Biol Chem. 2004. PMID: 14998996 Free article.

8

Synthesis of psymberin analogues: probing a functional correlation with the pederin/mycalamide family of natural products.

Jiang X, Williams N, De Brabander JK. Jiang X, et al. Among authors: de brabander jk. Org Lett. 2007 Jan 18;9(2):227-30. doi: 10.1021/ol062656o. Org Lett. 2007. PMID: 17217271 Free PMC article.

9

Development of proneurogenic, neuroprotective small molecules.

MacMillan KS, Naidoo J, Liang J, Melito L, Williams NS, Morlock L, Huntington PJ, Estill SJ, Longgood J, Becker GL, McKnight SL, Pieper AA, De Brabander JK, Ready JM. MacMillan KS, et al. Among authors: de brabander jk. J Am Chem Soc. 2011 Feb 9;133(5):1428-37. doi: 10.1021/ja108211m. Epub 2011 Jan 6. J Am Chem Soc. 2011. PMID: 21210688 Free PMC article.

10

Studies toward the unique pederin family member psymberin: structure-activity relationships, biochemical studies, and genetics identify the mode-of-action of psymberin.

Wu CY, Feng Y, Cardenas ER, Williams N, Floreancig PE, De Brabander JK, Roth MG. Wu CY, et al. Among authors: de brabander jk. J Am Chem Soc. 2012 Nov 21;134(46):18998-9003. doi: 10.1021/ja3057002. Epub 2012 Nov 13. J Am Chem Soc. 2012. PMID: 23088155 Free PMC article.

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