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Engineered human hepatocyte organoids enable CRISPR-based target discovery and drug screening for steatosis.
Hendriks D, Brouwers JF, Hamer K, Geurts MH, Luciana L, Massalini S, López-Iglesias C, Peters PJ, Rodríguez-Colman MJ, Chuva de Sousa Lopes S, Artegiani B, Clevers H. Hendriks D, et al. Among authors: brouwers jf. Nat Biotechnol. 2023 Nov;41(11):1567-1581. doi: 10.1038/s41587-023-01680-4. Epub 2023 Feb 23. Nat Biotechnol. 2023. PMID: 36823355 Free PMC article.
A novel host-parasite lipid cross-talk. Schistosomal lyso-phosphatidylserine activates toll-like receptor 2 and affects immune polarization.
van der Kleij D, Latz E, Brouwers JF, Kruize YC, Schmitz M, Kurt-Jones EA, Espevik T, de Jong EC, Kapsenberg ML, Golenbock DT, Tielens AG, Yazdanbakhsh M. van der Kleij D, et al. Among authors: brouwers jf. J Biol Chem. 2002 Dec 13;277(50):48122-9. doi: 10.1074/jbc.M206941200. Epub 2002 Sep 30. J Biol Chem. 2002. PMID: 12359728 Free article.
Aberrant hepatic lipid storage and metabolism in canine portosystemic shunts.
Van den Bossche L, Schoonenberg VAC, Burgener IA, Penning LC, Schrall IM, Kruitwagen HS, van Wolferen ME, Grinwis GCM, Kummeling A, Rothuizen J, van Velzen JF, Stathonikos N, Molenaar MR, Helms BJ, Brouwers JFHM, Spee B, van Steenbeek FG. Van den Bossche L, et al. Among authors: brouwers jfhm. PLoS One. 2017 Oct 19;12(10):e0186491. doi: 10.1371/journal.pone.0186491. eCollection 2017. PLoS One. 2017. PMID: 29049355 Free PMC article.
94 results