Joshua-Tor L - Search Results

1

A shape-shifting nuclease unravels structured RNA.

Meze K, Axhemi A, Thomas DR, Doymaz A, Joshua-Tor L. Meze K, et al. Among authors: joshua tor l. Nat Struct Mol Biol. 2023 Mar;30(3):339-347. doi: 10.1038/s41594-023-00923-x. Epub 2023 Feb 23. Nat Struct Mol Biol. 2023. PMID: 36823385 Free PMC article.

2

The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes.

Song JJ, Liu J, Tolia NH, Schneiderman J, Smith SK, Martienssen RA, Hannon GJ, Joshua-Tor L. Song JJ, et al. Nat Struct Biol. 2003 Dec;10(12):1026-32. doi: 10.1038/nsb1016. Epub 2003 Nov 16. Nat Struct Biol. 2003. PMID: 14625589

3

The Chp1-Tas3 core is a multifunctional platform critical for gene silencing by RITS.

Schalch T, Job G, Shanker S, Partridge JF, Joshua-Tor L. Schalch T, et al. Nat Struct Mol Biol. 2011 Nov 13;18(12):1351-7. doi: 10.1038/nsmb.2151. Nat Struct Mol Biol. 2011. PMID: 22081013 Free PMC article.

4

The structural biochemistry of Zucchini implicates it as a nuclease in piRNA biogenesis.

Ipsaro JJ, Haase AD, Knott SR, Joshua-Tor L, Hannon GJ. Ipsaro JJ, et al. Nature. 2012 Nov 8;491(7423):279-83. doi: 10.1038/nature11502. Epub 2012 Oct 14. Nature. 2012. PMID: 23064227 Free PMC article.

5

Mechanism of Dis3l2 substrate recognition in the Lin28-let-7 pathway.

Faehnle CR, Walleshauser J, Joshua-Tor L. Faehnle CR, et al. Nature. 2014 Oct 9;514(7521):252-256. doi: 10.1038/nature13553. Epub 2014 Aug 3. Nature. 2014. PMID: 25119025 Free PMC article.

6

From guide to target: molecular insights into eukaryotic RNA-interference machinery.

Ipsaro JJ, Joshua-Tor L. Ipsaro JJ, et al. Nat Struct Mol Biol. 2015 Jan;22(1):20-8. doi: 10.1038/nsmb.2931. Nat Struct Mol Biol. 2015. PMID: 25565029 Free PMC article. Review.

7

Multi-domain utilization by TUT4 and TUT7 in control of let-7 biogenesis.

Faehnle CR, Walleshauser J, Joshua-Tor L. Faehnle CR, et al. Nat Struct Mol Biol. 2017 Aug;24(8):658-665. doi: 10.1038/nsmb.3428. Epub 2017 Jul 3. Nat Struct Mol Biol. 2017. PMID: 28671666 Free PMC article.

8

High-resolution cryo-EM structures of outbreak strain human norovirus shells reveal size variations.

Jung J, Grant T, Thomas DR, Diehnelt CW, Grigorieff N, Joshua-Tor L. Jung J, et al. Proc Natl Acad Sci U S A. 2019 Jun 25;116(26):12828-12832. doi: 10.1073/pnas.1903562116. Epub 2019 Jun 10. Proc Natl Acad Sci U S A. 2019. PMID: 31182604 Free PMC article.

9

The dynamic nature of the human origin recognition complex revealed through five cryoEM structures.

Jaremko MJ, On KF, Thomas DR, Stillman B, Joshua-Tor L. Jaremko MJ, et al. Elife. 2020 Aug 18;9:e58622. doi: 10.7554/eLife.58622. Elife. 2020. PMID: 32808929 Free PMC article.

10

Crystal structure of Apaf-1 caspase recruitment domain: an alpha-helical Greek key fold for apoptotic signaling.

Vaughn DE, Rodriguez J, Lazebnik Y, Joshua-Tor L. Vaughn DE, et al. J Mol Biol. 1999 Oct 29;293(3):439-47. doi: 10.1006/jmbi.1999.3177. J Mol Biol. 1999. PMID: 10543941

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