DiMaio D - Search Results

1

Designed Transmembrane Proteins Inhibit the Erythropoietin Receptor in a Custom Binding Topology.

Mravic M, He L, Kratochvil H, Hu H, Nick SE, Bai W, Edwards A, Jo H, Wu Y, DiMaio D, DeGrado WF. Mravic M, et al. Among authors: dimaio d. bioRxiv [Preprint]. 2023 Feb 15:2023.02.13.526773. doi: 10.1101/2023.02.13.526773. bioRxiv. 2023. PMID: 36824741 Free PMC article. Preprint.

2

Specific locations of hydrophilic amino acids in constructed transmembrane ligands of the platelet-derived growth factor beta receptor.

Freeman-Cook LL, Edwards AP, Dixon AM, Yates KE, Ely L, Engelman DM, Dimaio D. Freeman-Cook LL, et al. Among authors: dimaio d. J Mol Biol. 2005 Jan 28;345(4):907-21. doi: 10.1016/j.jmb.2004.10.072. J Mol Biol. 2005. PMID: 15588835

3

Productive interaction between transmembrane mutants of the bovine papillomavirus E5 protein and the platelet-derived growth factor beta receptor.

Lai CC, Edwards AP, DiMaio D. Lai CC, et al. Among authors: dimaio d. J Virol. 2005 Feb;79(3):1924-9. doi: 10.1128/JVI.79.3.1924-1929.2005. J Virol. 2005. PMID: 15650217 Free PMC article.

4

Packing contacts can mediate highly specific interactions between artificial transmembrane proteins and the PDGFbeta receptor.

Ptacek JB, Edwards AP, Freeman-Cook LL, DiMaio D. Ptacek JB, et al. Among authors: dimaio d. Proc Natl Acad Sci U S A. 2007 Jul 17;104(29):11945-50. doi: 10.1073/pnas.0704348104. Epub 2007 Jul 3. Proc Natl Acad Sci U S A. 2007. PMID: 17609376 Free PMC article.

5

Compensatory mutants of the bovine papillomavirus E5 protein and the platelet-derived growth factor β receptor reveal a complex direct transmembrane interaction.

Edwards AP, Xie Y, Bowers L, DiMaio D. Edwards AP, et al. Among authors: dimaio d. J Virol. 2013 Oct;87(20):10936-45. doi: 10.1128/JVI.01475-13. Epub 2013 Aug 7. J Virol. 2013. PMID: 23926343 Free PMC article.

6

Transmembrane Protein Aptamer Induces Cooperative Signaling by the EPO Receptor and the Cytokine Receptor β-Common Subunit.

He L, Cohen EB, Edwards APB, Xavier-Ferrucio J, Bugge K, Federman RS, Absher D, Myers RM, Kragelund BB, Krause DS, DiMaio D. He L, et al. Among authors: dimaio d. iScience. 2019 Jul 26;17:167-181. doi: 10.1016/j.isci.2019.06.027. Epub 2019 Jun 21. iScience. 2019. PMID: 31279934 Free PMC article.

7

De novo-designed transmembrane proteins bind and regulate a cytokine receptor.

Mravic M, He L, Kratochvil HT, Hu H, Nick SE, Bai W, Edwards A, Jo H, Wu Y, DiMaio D, DeGrado WF. Mravic M, et al. Among authors: dimaio d. Nat Chem Biol. 2024 Jun;20(6):751-760. doi: 10.1038/s41589-024-01562-z. Epub 2024 Mar 13. Nat Chem Biol. 2024. PMID: 38480980 Free PMC article.

8

Biologically active LIL proteins built with minimal chemical diversity.

Heim EN, Marston JL, Federman RS, Edwards AP, Karabadzhak AG, Petti LM, Engelman DM, DiMaio D. Heim EN, et al. Among authors: dimaio d. Proc Natl Acad Sci U S A. 2015 Aug 25;112(34):E4717-25. doi: 10.1073/pnas.1514230112. Epub 2015 Aug 10. Proc Natl Acad Sci U S A. 2015. PMID: 26261320 Free PMC article.

9

Two transmembrane dimers of the bovine papillomavirus E5 oncoprotein clamp the PDGF β receptor in an active dimeric conformation.

Karabadzhak AG, Petti LM, Barrera FN, Edwards APB, Moya-Rodríguez A, Polikanov YS, Freites JA, Tobias DJ, Engelman DM, DiMaio D. Karabadzhak AG, et al. Among authors: dimaio d. Proc Natl Acad Sci U S A. 2017 Aug 29;114(35):E7262-E7271. doi: 10.1073/pnas.1705622114. Epub 2017 Aug 14. Proc Natl Acad Sci U S A. 2017. PMID: 28808001 Free PMC article.

10

Single methyl groups can act as toggle switches to specify transmembrane Protein-protein interactions.

He L, Steinocher H, Shelar A, Cohen EB, Heim EN, Kragelund BB, Grigoryan G, DiMaio D. He L, et al. Among authors: dimaio d. Elife. 2017 Sep 4;6:e27701. doi: 10.7554/eLife.27701. Elife. 2017. PMID: 28869036 Free PMC article.

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