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A hyper-quiescent chromatin state formed during aging is reversed by regeneration.
Yang N, Occean JR, Melters DP, Shi C, Wang L, Stransky S, Doyle ME, Cui CY, Delannoy M, Fan J, Slama E, Egan JM, De S, Cunningham SC, de Cabo R, Sidoli S, Dalal Y, Sen P. Yang N, et al. Among authors: egan jm. bioRxiv [Preprint]. 2023 Feb 15:2023.02.14.528512. doi: 10.1101/2023.02.14.528512. bioRxiv. 2023. Update in: Mol Cell. 2023 May 18;83(10):1659-1676.e11. doi: 10.1016/j.molcel.2023.04.005. PMID: 36824822 Free PMC article. Updated. Preprint.
Human Taste Cells Express ACE2: a Portal for SARS-CoV-2 Infection.
Doyle ME, Appleton A, Liu QR, Yao Q, Mazucanti CH, Egan JM. Doyle ME, et al. Among authors: egan jm. bioRxiv [Preprint]. 2021 Apr 21:2021.04.21.440680. doi: 10.1101/2021.04.21.440680. bioRxiv. 2021. PMID: 33907747 Free PMC article. Preprint.
Physiology of the tongue with emphasis on taste transduction.
Doyle ME, Premathilake HU, Yao Q, Mazucanti CH, Egan JM. Doyle ME, et al. Among authors: egan jm. Physiol Rev. 2023 Apr 1;103(2):1193-1246. doi: 10.1152/physrev.00012.2022. Epub 2022 Nov 24. Physiol Rev. 2023. PMID: 36422992 Free PMC article. Review.
Longitudinal phenotypic aging metrics in the Baltimore Longitudinal Study of Aging.
Kuo PL, Schrack JA, Levine ME, Shardell MD, Simonsick EM, Chia CW, Moore AZ, Tanaka T, An Y, Karikkineth A, AlGhatrif M, Elango P, Zukley LM, Egan JM, de Cabo R, Resnick SM, Ferrucci L. Kuo PL, et al. Among authors: egan jm. Nat Aging. 2022 Jul;2(7):635-643. doi: 10.1038/s43587-022-00243-7. Epub 2022 Jul 18. Nat Aging. 2022. PMID: 36910594 Free PMC article.
A hyper-quiescent chromatin state formed during aging is reversed by regeneration.
Yang N, Occean JR, Melters DP, Shi C, Wang L, Stransky S, Doyle ME, Cui CY, Delannoy M, Fan J, Slama E, Egan JM, De S, Cunningham SC, de Cabo R, Sidoli S, Dalal Y, Sen P. Yang N, et al. Among authors: egan jm. Mol Cell. 2023 May 18;83(10):1659-1676.e11. doi: 10.1016/j.molcel.2023.04.005. Epub 2023 Apr 27. Mol Cell. 2023. PMID: 37116496 Free PMC article.
SARS-CoV-2 infection establishes a stable and age-independent CD8+ T cell response against a dominant nucleocapsid epitope using restricted T cell receptors.
Choy C, Chen J, Li J, Gallagher DT, Lu J, Wu D, Zou A, Hemani H, Baptiste BA, Wichmann E, Yang Q, Ciffelo J, Yin R, McKelvy J, Melvin D, Wallace T, Dunn C, Nguyen C, Chia CW, Fan J, Ruffolo J, Zukley L, Shi G, Amano T, An Y, Meirelles O, Wu WW, Chou CK, Shen RF, Willis RA, Ko MSH, Liu YT, De S, Pierce BG, Ferrucci L, Egan J, Mariuzza R, Weng NP. Choy C, et al. Nat Commun. 2023 Oct 23;14(1):6725. doi: 10.1038/s41467-023-42430-z. Nat Commun. 2023. PMID: 37872153 Free PMC article.
Long-Term Dysfunction of Taste Papillae in SARS-CoV-2.
Yao Q, Doyle ME, Liu QR, Appleton A, O'Connell JF, Weng NP, Egan JM. Yao Q, et al. Among authors: egan jm. NEJM Evid. 2023 Sep;2(9):10.1056/evidoa2300046. doi: 10.1056/evidoa2300046. Epub 2023 Jul 20. NEJM Evid. 2023. PMID: 38145006 Free PMC article.
Cerebrospinal fluid exploratory proteomics and ketamine metabolite pharmacokinetics in human volunteers after ketamine infusion.
Moaddel R, Farmer CA, Yavi M, Kadriu B, Zhu M, Fan J, Chen Q, Lehrmann E, Fantoni G, De S, Mazucanti CH, Acevedo-Diaz EE, Yuan P, Gould TD, Park LT, Egan JM, Ferrucci L, Zarate CA Jr. Moaddel R, et al. Among authors: egan jm. iScience. 2023 Nov 23;26(12):108527. doi: 10.1016/j.isci.2023.108527. eCollection 2023 Dec 15. iScience. 2023. PMID: 38162029 Free PMC article.
287 results